Caroxazone

DB09254

small molecule withdrawn

Deskripsi

Caroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. However, it presents a five-fold preference for the MAO-B subtype.

Struktur Molekul 2D

Berat 206.201
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1322 Data
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Caroxazone.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Caroxazone.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Caroxazone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Caroxazone.
Magnesium sulfate The therapeutic efficacy of Caroxazone can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Caroxazone may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Caroxazone may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Caroxazone.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Caroxazone.
Orphenadrine Caroxazone may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Caroxazone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Caroxazone.
Pramipexole Caroxazone may increase the sedative activities of Pramipexole.
Ropinirole Caroxazone may increase the sedative activities of Ropinirole.
Rotigotine Caroxazone may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Caroxazone.
Sodium oxybate Caroxazone may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Caroxazone may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Thalidomide Caroxazone may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Caroxazone may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Caroxazone.
Cyclosporine The risk or severity of hypertension can be increased when Cyclosporine is combined with Caroxazone.
Icosapent The risk or severity of hypertension can be increased when Icosapent is combined with Caroxazone.
Mesalazine The risk or severity of hypertension can be increased when Mesalazine is combined with Caroxazone.
Indomethacin The risk or severity of hypertension can be increased when Indomethacin is combined with Caroxazone.
Methylergometrine The risk or severity of hypertension can be increased when Methylergometrine is combined with Caroxazone.
Nabumetone The risk or severity of hypertension can be increased when Nabumetone is combined with Caroxazone.
Ketorolac The risk or severity of hypertension can be increased when Ketorolac is combined with Caroxazone.
Tenoxicam The risk or severity of hypertension can be increased when Tenoxicam is combined with Caroxazone.
Celecoxib The risk or severity of hypertension can be increased when Celecoxib is combined with Caroxazone.
Tolmetin The risk or severity of hypertension can be increased when Tolmetin is combined with Caroxazone.
Rofecoxib The risk or severity of hypertension can be increased when Rofecoxib is combined with Caroxazone.
Piroxicam The risk or severity of hypertension can be increased when Piroxicam is combined with Caroxazone.
Fenoprofen The risk or severity of hypertension can be increased when Fenoprofen is combined with Caroxazone.
Valdecoxib The risk or severity of hypertension can be increased when Valdecoxib is combined with Caroxazone.
Diclofenac The risk or severity of hypertension can be increased when Diclofenac is combined with Caroxazone.
Sulindac The risk or severity of hypertension can be increased when Sulindac is combined with Caroxazone.
Nicergoline The risk or severity of hypertension can be increased when Nicergoline is combined with Caroxazone.
Flurbiprofen The risk or severity of hypertension can be increased when Flurbiprofen is combined with Caroxazone.
Etodolac The risk or severity of hypertension can be increased when Etodolac is combined with Caroxazone.
Mefenamic acid The risk or severity of hypertension can be increased when Mefenamic acid is combined with Caroxazone.
Naproxen The risk or severity of hypertension can be increased when Naproxen is combined with Caroxazone.
Sulfasalazine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Caroxazone.
Phenylbutazone The risk or severity of hypertension can be increased when Phenylbutazone is combined with Caroxazone.
Meloxicam The risk or severity of hypertension can be increased when Meloxicam is combined with Caroxazone.
Carprofen The risk or severity of hypertension can be increased when Carprofen is combined with Caroxazone.
Phenmetrazine The risk or severity of hypertension can be increased when Phenmetrazine is combined with Caroxazone.
Diflunisal The risk or severity of hypertension can be increased when Diflunisal is combined with Caroxazone.
Salicylic acid The risk or severity of hypertension can be increased when Salicylic acid is combined with Caroxazone.
Meclofenamic acid The risk or severity of hypertension can be increased when Meclofenamic acid is combined with Caroxazone.
Dopamine The risk or severity of hypertension can be increased when Dopamine is combined with Caroxazone.
Oxaprozin The risk or severity of hypertension can be increased when Oxaprozin is combined with Caroxazone.
Ketoprofen The risk or severity of hypertension can be increased when Ketoprofen is combined with Caroxazone.
Balsalazide The risk or severity of hypertension can be increased when Balsalazide is combined with Caroxazone.
Ibuprofen The risk or severity of hypertension can be increased when Ibuprofen is combined with Caroxazone.
Dutasteride The risk or severity of hypertension can be increased when Dutasteride is combined with Caroxazone.
Propafenone The risk or severity of hypertension can be increased when Propafenone is combined with Caroxazone.
Finasteride The risk or severity of hypertension can be increased when Finasteride is combined with Caroxazone.
Lumiracoxib The risk or severity of hypertension can be increased when Lumiracoxib is combined with Caroxazone.
Ephedrine The risk or severity of hypertension can be increased when Ephedrine is combined with Caroxazone.
Magnesium salicylate The risk or severity of hypertension can be increased when Magnesium salicylate is combined with Caroxazone.
Salsalate The risk or severity of hypertension can be increased when Salsalate is combined with Caroxazone.
Choline magnesium trisalicylate The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Caroxazone.
Antrafenine The risk or severity of hypertension can be increased when Antrafenine is combined with Caroxazone.
Aminophenazone The risk or severity of hypertension can be increased when Aminophenazone is combined with Caroxazone.
Antipyrine The risk or severity of hypertension can be increased when Antipyrine is combined with Caroxazone.
Tiaprofenic acid The risk or severity of hypertension can be increased when Tiaprofenic acid is combined with Caroxazone.
Etoricoxib The risk or severity of hypertension can be increased when Etoricoxib is combined with Caroxazone.
Epicaptopril The risk or severity of hypertension can be increased when Epicaptopril is combined with Caroxazone.
Taxifolin The risk or severity of hypertension can be increased when Taxifolin is combined with Caroxazone.
Oxyphenbutazone The risk or severity of hypertension can be increased when Oxyphenbutazone is combined with Caroxazone.
1-benzylimidazole The risk or severity of hypertension can be increased when 1-benzylimidazole is combined with Caroxazone.
Benoxaprofen The risk or severity of hypertension can be increased when Benoxaprofen is combined with Caroxazone.
Metamizole The risk or severity of hypertension can be increased when Metamizole is combined with Caroxazone.
Zomepirac The risk or severity of hypertension can be increased when Zomepirac is combined with Caroxazone.
Dronedarone The risk or severity of hypertension can be increased when Dronedarone is combined with Caroxazone.
Cimicoxib The risk or severity of hypertension can be increased when Cimicoxib is combined with Caroxazone.
Amibegron The risk or severity of hypertension can be increased when Amibegron is combined with Caroxazone.
Nylidrin The risk or severity of hypertension can be increased when Nylidrin is combined with Caroxazone.
Solabegron The risk or severity of hypertension can be increased when Solabegron is combined with Caroxazone.
Lornoxicam The risk or severity of hypertension can be increased when Lornoxicam is combined with Caroxazone.
Aceclofenac The risk or severity of hypertension can be increased when Aceclofenac is combined with Caroxazone.
Zaltoprofen The risk or severity of hypertension can be increased when Zaltoprofen is combined with Caroxazone.
Saralasin The risk or severity of hypertension can be increased when Saralasin is combined with Caroxazone.
Azapropazone The risk or severity of hypertension can be increased when Azapropazone is combined with Caroxazone.
Parecoxib The risk or severity of hypertension can be increased when Parecoxib is combined with Caroxazone.
Salicylamide The risk or severity of hypertension can be increased when Salicylamide is combined with Caroxazone.
Tyramine The risk or severity of hypertension can be increased when Tyramine is combined with Caroxazone.
Mirabegron The risk or severity of hypertension can be increased when Mirabegron is combined with Caroxazone.
Adrafinil The risk or severity of hypertension can be increased when Adrafinil is combined with Caroxazone.
Kebuzone The risk or severity of hypertension can be increased when Kebuzone is combined with Caroxazone.
Isoxicam The risk or severity of hypertension can be increased when Isoxicam is combined with Caroxazone.
Indoprofen The risk or severity of hypertension can be increased when Indoprofen is combined with Caroxazone.
Ibuproxam The risk or severity of hypertension can be increased when Ibuproxam is combined with Caroxazone.
Floctafenine The risk or severity of hypertension can be increased when Floctafenine is combined with Caroxazone.
Fenbufen The risk or severity of hypertension can be increased when Fenbufen is combined with Caroxazone.
Etofenamate The risk or severity of hypertension can be increased when Etofenamate is combined with Caroxazone.
Etilefrine The risk or severity of hypertension can be increased when Etilefrine is combined with Caroxazone.
Epirizole The risk or severity of hypertension can be increased when Epirizole is combined with Caroxazone.
Benzydamine The risk or severity of hypertension can be increased when Benzydamine is combined with Caroxazone.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 359383
    Cecchini S, Petri P, Ardito R, Bareggi SR, Torriti A: A comparative double-blind trial of the new antidepressant caroxazone and amitriptyline. J Int Med Res. 1978;6(5):388-94.
  • PMID: 7272163
    Moretti A, Caccia C, Martini A, Bonollo L, Amico A, Sega R, Nicolella V, Nicolis FB: Effect of caroxazone, a new antidepressant drug, on monoamine oxidases in healthy volunteers. Br J Clin Pharmacol. 1981 May;11(5):511-5.

Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
  • Surodil
  • Timostenil

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul