Pheniprazine

DB09250

small molecule withdrawn

Deskripsi

Pheniprazine is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant in the 1960s. In addition, it was used for the treatment of other conditions, such as angina pectoris and schizophrenia. Pheniprazine was withdrawn by its manufacturer due to its ability to cause toxicity in the liver and its ability to cause optic neuritis.

Struktur Molekul 2D

Berat 150.225
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1322 Data
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Pheniprazine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Pheniprazine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Pheniprazine.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pheniprazine.
Magnesium sulfate The therapeutic efficacy of Pheniprazine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Pheniprazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Pheniprazine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Pheniprazine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Pheniprazine.
Orphenadrine Pheniprazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Pheniprazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Pheniprazine.
Pramipexole Pheniprazine may increase the sedative activities of Pramipexole.
Ropinirole Pheniprazine may increase the sedative activities of Ropinirole.
Rotigotine Pheniprazine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Pheniprazine.
Sodium oxybate Pheniprazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Pheniprazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Thalidomide Pheniprazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Pheniprazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Pheniprazine.
Cyclosporine The risk or severity of hypertension can be increased when Cyclosporine is combined with Pheniprazine.
Icosapent The risk or severity of hypertension can be increased when Icosapent is combined with Pheniprazine.
Mesalazine The risk or severity of hypertension can be increased when Mesalazine is combined with Pheniprazine.
Indomethacin The risk or severity of hypertension can be increased when Indomethacin is combined with Pheniprazine.
Methylergometrine The risk or severity of hypertension can be increased when Methylergometrine is combined with Pheniprazine.
Nabumetone The risk or severity of hypertension can be increased when Nabumetone is combined with Pheniprazine.
Ketorolac The risk or severity of hypertension can be increased when Ketorolac is combined with Pheniprazine.
Tenoxicam The risk or severity of hypertension can be increased when Tenoxicam is combined with Pheniprazine.
Celecoxib The risk or severity of hypertension can be increased when Celecoxib is combined with Pheniprazine.
Tolmetin The risk or severity of hypertension can be increased when Tolmetin is combined with Pheniprazine.
Rofecoxib The risk or severity of hypertension can be increased when Rofecoxib is combined with Pheniprazine.
Piroxicam The risk or severity of hypertension can be increased when Piroxicam is combined with Pheniprazine.
Fenoprofen The risk or severity of hypertension can be increased when Fenoprofen is combined with Pheniprazine.
Valdecoxib The risk or severity of hypertension can be increased when Valdecoxib is combined with Pheniprazine.
Diclofenac The risk or severity of hypertension can be increased when Diclofenac is combined with Pheniprazine.
Sulindac The risk or severity of hypertension can be increased when Sulindac is combined with Pheniprazine.
Nicergoline The risk or severity of hypertension can be increased when Nicergoline is combined with Pheniprazine.
Flurbiprofen The risk or severity of hypertension can be increased when Flurbiprofen is combined with Pheniprazine.
Etodolac The risk or severity of hypertension can be increased when Etodolac is combined with Pheniprazine.
Mefenamic acid The risk or severity of hypertension can be increased when Mefenamic acid is combined with Pheniprazine.
Naproxen The risk or severity of hypertension can be increased when Naproxen is combined with Pheniprazine.
Sulfasalazine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Pheniprazine.
Phenylbutazone The risk or severity of hypertension can be increased when Phenylbutazone is combined with Pheniprazine.
Meloxicam The risk or severity of hypertension can be increased when Meloxicam is combined with Pheniprazine.
Carprofen The risk or severity of hypertension can be increased when Carprofen is combined with Pheniprazine.
Phenmetrazine The risk or severity of hypertension can be increased when Phenmetrazine is combined with Pheniprazine.
Diflunisal The risk or severity of hypertension can be increased when Diflunisal is combined with Pheniprazine.
Salicylic acid The risk or severity of hypertension can be increased when Salicylic acid is combined with Pheniprazine.
Meclofenamic acid The risk or severity of hypertension can be increased when Meclofenamic acid is combined with Pheniprazine.
Dopamine The risk or severity of hypertension can be increased when Dopamine is combined with Pheniprazine.
Oxaprozin The risk or severity of hypertension can be increased when Oxaprozin is combined with Pheniprazine.
Ketoprofen The risk or severity of hypertension can be increased when Ketoprofen is combined with Pheniprazine.
Balsalazide The risk or severity of hypertension can be increased when Balsalazide is combined with Pheniprazine.
Ibuprofen The risk or severity of hypertension can be increased when Ibuprofen is combined with Pheniprazine.
Dutasteride The risk or severity of hypertension can be increased when Dutasteride is combined with Pheniprazine.
Propafenone The risk or severity of hypertension can be increased when Propafenone is combined with Pheniprazine.
Finasteride The risk or severity of hypertension can be increased when Finasteride is combined with Pheniprazine.
Lumiracoxib The risk or severity of hypertension can be increased when Lumiracoxib is combined with Pheniprazine.
Ephedrine The risk or severity of hypertension can be increased when Ephedrine is combined with Pheniprazine.
Magnesium salicylate The risk or severity of hypertension can be increased when Magnesium salicylate is combined with Pheniprazine.
Salsalate The risk or severity of hypertension can be increased when Salsalate is combined with Pheniprazine.
Choline magnesium trisalicylate The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Pheniprazine.
Antrafenine The risk or severity of hypertension can be increased when Antrafenine is combined with Pheniprazine.
Aminophenazone The risk or severity of hypertension can be increased when Aminophenazone is combined with Pheniprazine.
Antipyrine The risk or severity of hypertension can be increased when Antipyrine is combined with Pheniprazine.
Tiaprofenic acid The risk or severity of hypertension can be increased when Tiaprofenic acid is combined with Pheniprazine.
Etoricoxib The risk or severity of hypertension can be increased when Etoricoxib is combined with Pheniprazine.
Epicaptopril The risk or severity of hypertension can be increased when Epicaptopril is combined with Pheniprazine.
Taxifolin The risk or severity of hypertension can be increased when Taxifolin is combined with Pheniprazine.
Oxyphenbutazone The risk or severity of hypertension can be increased when Oxyphenbutazone is combined with Pheniprazine.
1-benzylimidazole The risk or severity of hypertension can be increased when 1-benzylimidazole is combined with Pheniprazine.
Benoxaprofen The risk or severity of hypertension can be increased when Benoxaprofen is combined with Pheniprazine.
Metamizole The risk or severity of hypertension can be increased when Metamizole is combined with Pheniprazine.
Zomepirac The risk or severity of hypertension can be increased when Zomepirac is combined with Pheniprazine.
Dronedarone The risk or severity of hypertension can be increased when Dronedarone is combined with Pheniprazine.
Cimicoxib The risk or severity of hypertension can be increased when Cimicoxib is combined with Pheniprazine.
Amibegron The risk or severity of hypertension can be increased when Amibegron is combined with Pheniprazine.
Nylidrin The risk or severity of hypertension can be increased when Nylidrin is combined with Pheniprazine.
Solabegron The risk or severity of hypertension can be increased when Solabegron is combined with Pheniprazine.
Lornoxicam The risk or severity of hypertension can be increased when Lornoxicam is combined with Pheniprazine.
Aceclofenac The risk or severity of hypertension can be increased when Aceclofenac is combined with Pheniprazine.
Zaltoprofen The risk or severity of hypertension can be increased when Zaltoprofen is combined with Pheniprazine.
Saralasin The risk or severity of hypertension can be increased when Saralasin is combined with Pheniprazine.
Azapropazone The risk or severity of hypertension can be increased when Azapropazone is combined with Pheniprazine.
Parecoxib The risk or severity of hypertension can be increased when Parecoxib is combined with Pheniprazine.
Salicylamide The risk or severity of hypertension can be increased when Salicylamide is combined with Pheniprazine.
Tyramine The risk or severity of hypertension can be increased when Tyramine is combined with Pheniprazine.
Mirabegron The risk or severity of hypertension can be increased when Mirabegron is combined with Pheniprazine.
Adrafinil The risk or severity of hypertension can be increased when Adrafinil is combined with Pheniprazine.
Kebuzone The risk or severity of hypertension can be increased when Kebuzone is combined with Pheniprazine.
Isoxicam The risk or severity of hypertension can be increased when Isoxicam is combined with Pheniprazine.
Indoprofen The risk or severity of hypertension can be increased when Indoprofen is combined with Pheniprazine.
Ibuproxam The risk or severity of hypertension can be increased when Ibuproxam is combined with Pheniprazine.
Floctafenine The risk or severity of hypertension can be increased when Floctafenine is combined with Pheniprazine.
Fenbufen The risk or severity of hypertension can be increased when Fenbufen is combined with Pheniprazine.
Etofenamate The risk or severity of hypertension can be increased when Etofenamate is combined with Pheniprazine.
Etilefrine The risk or severity of hypertension can be increased when Etilefrine is combined with Pheniprazine.
Epirizole The risk or severity of hypertension can be increased when Epirizole is combined with Pheniprazine.
Benzydamine The risk or severity of hypertension can be increased when Benzydamine is combined with Pheniprazine.

Referensi & Sumber

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