Niguldipine

DB09239

small molecule experimental

Deskripsi

Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.

Struktur Molekul 2D

Berat 609.723
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1421 Data
Afatinib The serum concentration of Afatinib can be increased when it is combined with Niguldipine.
Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Niguldipine.
Brentuximab vedotin The serum concentration of Brentuximab vedotin can be increased when it is combined with Niguldipine.
Colchicine The serum concentration of Colchicine can be increased when it is combined with Niguldipine.
Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Niguldipine.
Ledipasvir The serum concentration of Ledipasvir can be increased when it is combined with Niguldipine.
Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Niguldipine.
Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Niguldipine.
Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Niguldipine.
Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Niguldipine.
Silodosin The excretion of Silodosin can be decreased when combined with Niguldipine.
Topotecan The serum concentration of Topotecan can be increased when it is combined with Niguldipine.
Ceritinib Niguldipine may increase the bradycardic activities of Ceritinib.
Ivabradine Niguldipine may increase the bradycardic activities of Ivabradine.
Ruxolitinib Ruxolitinib may increase the bradycardic activities of Niguldipine.
Amifostine Niguldipine may increase the hypotensive activities of Amifostine.
Diazoxide Diazoxide may increase the hypotensive activities of Niguldipine.
Methylphenidate Methylphenidate may decrease the antihypertensive activities of Niguldipine.
Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Niguldipine.
Obinutuzumab Niguldipine may increase the hypotensive activities of Obinutuzumab.
Pentoxifylline Pentoxifylline may increase the hypotensive activities of Niguldipine.
Rituximab Niguldipine may increase the hypotensive activities of Rituximab.
Desmopressin Desmopressin may decrease the antihypertensive activities of Niguldipine.
Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Niguldipine.
Doxapram Doxapram may decrease the antihypertensive activities of Niguldipine.
Phenmetrazine Phenmetrazine may decrease the antihypertensive activities of Niguldipine.
Naratriptan Naratriptan may decrease the antihypertensive activities of Niguldipine.
Rizatriptan Rizatriptan may decrease the antihypertensive activities of Niguldipine.
Dopamine Dopamine may decrease the antihypertensive activities of Niguldipine.
Frovatriptan Frovatriptan may decrease the antihypertensive activities of Niguldipine.
Epicaptopril Epicaptopril may decrease the antihypertensive activities of Niguldipine.
1-benzylimidazole 1-benzylimidazole may decrease the antihypertensive activities of Niguldipine.
Amineptine Amineptine may decrease the antihypertensive activities of Niguldipine.
Naluzotan Naluzotan may decrease the antihypertensive activities of Niguldipine.
Esmirtazapine Esmirtazapine may decrease the antihypertensive activities of Niguldipine.
Nitrous oxide Nitrous oxide may decrease the antihypertensive activities of Niguldipine.
Cinitapride Cinitapride may decrease the antihypertensive activities of Niguldipine.
Tyramine Tyramine may decrease the antihypertensive activities of Niguldipine.
Ifenprodil Ifenprodil may decrease the antihypertensive activities of Niguldipine.
Dimetacrine Dimetacrine may decrease the antihypertensive activities of Niguldipine.
Moxisylyte Moxisylyte may decrease the antihypertensive activities of Niguldipine.
Oxaprotiline Oxaprotiline may decrease the antihypertensive activities of Niguldipine.
Atipamezole Atipamezole may decrease the antihypertensive activities of Niguldipine.
Tetrahydrocannabivarin Tetrahydrocannabivarin may decrease the antihypertensive activities of Niguldipine.
Piclozotan Piclozotan may decrease the antihypertensive activities of Niguldipine.
Idazoxan Idazoxan may decrease the antihypertensive activities of Niguldipine.
Opipramol Opipramol may decrease the antihypertensive activities of Niguldipine.
Tramazoline Tramazoline may decrease the antihypertensive activities of Niguldipine.
Amitriptylinoxide Amitriptylinoxide may decrease the antihypertensive activities of Niguldipine.
Dibenzepin Dibenzepin may decrease the antihypertensive activities of Niguldipine.
Quinupramine Quinupramine may decrease the antihypertensive activities of Niguldipine.
Trichloroethylene Trichloroethylene may decrease the antihypertensive activities of Niguldipine.
Fenozolone Fenozolone may decrease the antihypertensive activities of Niguldipine.
Melitracen Melitracen may decrease the antihypertensive activities of Niguldipine.
Lofepramine Lofepramine may decrease the antihypertensive activities of Niguldipine.
Xenon Xenon may decrease the antihypertensive activities of Niguldipine.
Iprindole Iprindole may decrease the antihypertensive activities of Niguldipine.
Buflomedil Buflomedil may decrease the antihypertensive activities of Niguldipine.
Metergoline Metergoline may decrease the antihypertensive activities of Niguldipine.
Diethyl ether Diethyl ether may decrease the antihypertensive activities of Niguldipine.
Imipramine oxide Imipramine oxide may decrease the antihypertensive activities of Niguldipine.
Mefenorex Mefenorex may decrease the antihypertensive activities of Niguldipine.
5-methoxy-N,N-dimethyltryptamine 5-methoxy-N,N-dimethyltryptamine may decrease the antihypertensive activities of Niguldipine.
Quinoline Yellow WS Quinoline Yellow WS may decrease the antihypertensive activities of Niguldipine.
Solriamfetol Solriamfetol may decrease the antihypertensive activities of Niguldipine.
Remifentanil Remifentanil may decrease the antihypertensive activities of Niguldipine.
Dutasteride Dutasteride may decrease the antihypertensive activities of Niguldipine.
Methysergide Methysergide may decrease the antihypertensive activities of Niguldipine.
Methylergometrine Methylergometrine may decrease the antihypertensive activities of Niguldipine.
Buspirone Buspirone may decrease the antihypertensive activities of Niguldipine.
Lisuride Lisuride may decrease the antihypertensive activities of Niguldipine.
Sufentanil Sufentanil may decrease the antihypertensive activities of Niguldipine.
Alfentanil Alfentanil may decrease the antihypertensive activities of Niguldipine.
Fentanyl Fentanyl may decrease the antihypertensive activities of Niguldipine.
Almotriptan Almotriptan may decrease the antihypertensive activities of Niguldipine.
Methoxyflurane Methoxyflurane may decrease the antihypertensive activities of Niguldipine.
Ergoloid mesylate Ergoloid mesylate may decrease the antihypertensive activities of Niguldipine.
Halothane Halothane may decrease the antihypertensive activities of Niguldipine.
Finasteride Finasteride may decrease the antihypertensive activities of Niguldipine.
Yohimbine Yohimbine may decrease the antihypertensive activities of Niguldipine.
Lysergic acid diethylamide Lysergic acid diethylamide may decrease the antihypertensive activities of Niguldipine.
Flibanserin Flibanserin may decrease the antihypertensive activities of Niguldipine.
Rotigotine Rotigotine may decrease the antihypertensive activities of Niguldipine.
Cariprazine Cariprazine may decrease the antihypertensive activities of Niguldipine.
Mianserin Mianserin may decrease the antihypertensive activities of Niguldipine.
Vilazodone Vilazodone may decrease the antihypertensive activities of Niguldipine.
Cannabidiol Cannabidiol may decrease the antihypertensive activities of Niguldipine.
Vortioxetine Vortioxetine may decrease the antihypertensive activities of Niguldipine.
Tianeptine Tianeptine may decrease the antihypertensive activities of Niguldipine.
Dihydroergocornine Dihydroergocornine may decrease the antihypertensive activities of Niguldipine.
Siponimod Siponimod may decrease the antihypertensive activities of Niguldipine.
Dihydroergocristine Dihydroergocristine may decrease the antihypertensive activities of Niguldipine.
Dihydroergocryptine Dihydroergocryptine may decrease the antihypertensive activities of Niguldipine.
Terguride Terguride may decrease the antihypertensive activities of Niguldipine.
Eletriptan Eletriptan may decrease the antihypertensive activities of Niguldipine.
Sumatriptan Sumatriptan may decrease the antihypertensive activities of Niguldipine.
Acetylsalicylic acid Acetylsalicylic acid may decrease the antihypertensive activities of Niguldipine.
Selpercatinib Selpercatinib may decrease the antihypertensive activities of Niguldipine.
Naxitamab Naxitamab may decrease the antihypertensive activities of Niguldipine.
Everolimus The serum concentration of Everolimus can be increased when it is combined with Niguldipine.

Target Protein

Alpha-1A adrenergic receptor ADRA1A

Referensi & Sumber

Artikel (PubMed)
  • PMID: 2548881
    Boer R, Grassegger A, Schudt C, Glossmann H: (+)-Niguldipine binds with very high affinity to Ca2+ channels and to a subtype of alpha 1-adrenoceptors. Eur J Pharmacol. 1989 May 11;172(2):131-45.

Contoh Produk & Brand

Produk: 0 • International brands: 0
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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