Bisoxatin

DB09219

small molecule approved

Deskripsi

Bisoxatin is a stimulant laxative which increases peristalsis and inhibits absorbtion of water and ions in the intestine L926. It is marketed in Belgium under the tradename Wylaxine and used for the treatment of constipation and for preparation of the colon for surgical procedures.

Struktur Molekul 2D

Berat 333.343
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Once dissociated from acetate, some bisoxatin is absorbed with a Tmax of 4 h L926.

Metabolisme

Absorbed compound is metabolized to bisoxatin glucuronide L926.

Rute Eliminasi

Primarily excreted in the feces 48-72 h after administration as the free parent compound with a small amount remaining as the acetate salt L926. Bisoxatin glucuronide and a trace amount of parent compound are eliminated in the urine.

Interaksi Obat

1016 Data
Trospium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Trospium.
Oxyphenonium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Oxyphenonium.
Ziprasidone The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Ziprasidone.
Ipratropium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Ipratropium.
Olanzapine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Olanzapine.
Metixene The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Metixene.
Terfenadine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Terfenadine.
Buclizine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Buclizine.
Doxylamine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Doxylamine.
Trihexyphenidyl The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Trihexyphenidyl.
Oxyphencyclimine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Oxyphencyclimine.
Procyclidine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Procyclidine.
Profenamine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Profenamine.
Promazine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Promazine.
Hyoscyamine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Hyoscyamine.
Cyproheptadine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Cyproheptadine.
Methscopolamine bromide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Methscopolamine bromide.
Gallamine triethiodide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Gallamine triethiodide.
Darifenacin The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Darifenacin.
Tridihexethyl The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Tridihexethyl.
Triflupromazine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Triflupromazine.
Anisotropine methylbromide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Anisotropine methylbromide.
Nortriptyline The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Nortriptyline.
Amoxapine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Amoxapine.
Atropine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Atropine.
Nicardipine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Nicardipine.
Pirenzepine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Pirenzepine.
Paroxetine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Paroxetine.
Homatropine methylbromide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Homatropine methylbromide.
Rocuronium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Rocuronium.
Scopolamine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Scopolamine.
Benzquinamide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Benzquinamide.
Clidinium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Clidinium.
Propiomazine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Propiomazine.
Biperiden The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Biperiden.
Brompheniramine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Brompheniramine.
Flupentixol The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Flupentixol.
Cocaine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Cocaine.
Methantheline The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Methantheline.
Cycrimine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Cycrimine.
Glycopyrronium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Glycopyrronium.
Oxybutynin The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Oxybutynin.
Diphenhydramine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Diphenhydramine.
Orphenadrine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Orphenadrine.
Escitalopram The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Escitalopram.
Mivacurium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Mivacurium.
Diphenidol The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Diphenidol.
Aripiprazole The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Aripiprazole.
Chlorprothixene The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Chlorprothixene.
Metocurine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Metocurine.
Pancuronium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Pancuronium.
Pipecuronium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Pipecuronium.
Methotrimeprazine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Methotrimeprazine.
Solifenacin The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Solifenacin.
Isopropamide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Isopropamide.
Rapacuronium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Rapacuronium.
Mepenzolate The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Mepenzolate.
Pizotifen The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Pizotifen.
Hexocyclium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Hexocyclium.
Dimetindene The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Dimetindene.
Dexetimide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Dexetimide.
Benactyzine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Benactyzine.
Umeclidinium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Umeclidinium.
Dosulepin The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Dosulepin.
Butylscopolamine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Butylscopolamine.
Thonzylamine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Thonzylamine.
Methscopolamine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Methscopolamine.
Revefenacin The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Revefenacin.
Oxitropium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Oxitropium.
Batefenterol The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Batefenterol.
Mebeverine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Mebeverine.
Tropatepine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Tropatepine.
Prifinium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Prifinium.
Piperidolate The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Piperidolate.
Benzilone The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Benzilone.
Difemerine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Difemerine.
Phenglutarimide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Phenglutarimide.
Mazaticol The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Mazaticol.
Etybenzatropine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Etybenzatropine.
Otilonium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Otilonium.
Emepronium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Emepronium.
Poldine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Poldine.
Bevonium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Bevonium.
Rociverine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Rociverine.
Bornaprine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Bornaprine.
Etanautine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Etanautine.
Tiemonium iodide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Tiemonium iodide.
Dihexyverine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Dihexyverine.
Penthienate The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Penthienate.
Diphemanil The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Diphemanil.
Camylofin The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Camylofin.
Fenpiverinium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Fenpiverinium.
Emetonium iodide The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Emetonium iodide.
Pipenzolate The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Pipenzolate.
Timepidium The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Timepidium.
Desipramine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Desipramine.
Chlorphenoxamine The therapeutic efficacy of Bisoxatin can be decreased when used in combination with Chlorphenoxamine.
Torasemide The risk or severity of dehydration can be increased when Torasemide is combined with Bisoxatin.
Methyclothiazide The risk or severity of dehydration can be increased when Methyclothiazide is combined with Bisoxatin.
Chlorthalidone The risk or severity of dehydration can be increased when Chlorthalidone is combined with Bisoxatin.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Wylaxine — Omega Pharma Belgium

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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