Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine.
The similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source of some confusion however m-synephrine refers to a related drug more commonly known as phenylephrine. While the compounds share some chemical and pharmacological similarities, they are in fact distinct chemical entities.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Valsartan | Synephrine may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Synephrine may decrease the antihypertensive activities of Ramipril. |
| Reserpine | Synephrine may decrease the antihypertensive activities of Reserpine. |
| Remikiren | Synephrine may decrease the antihypertensive activities of Remikiren. |
| Torasemide | Synephrine may decrease the antihypertensive activities of Torasemide. |
| Isradipine | Synephrine may decrease the antihypertensive activities of Isradipine. |
| Olmesartan | Synephrine may decrease the antihypertensive activities of Olmesartan. |
| Chlorthalidone | Synephrine may decrease the antihypertensive activities of Chlorthalidone. |
| Nitroprusside | Synephrine may decrease the antihypertensive activities of Nitroprusside. |
| Diltiazem | Synephrine may decrease the antihypertensive activities of Diltiazem. |
| Minoxidil | Synephrine may decrease the antihypertensive activities of Minoxidil. |
| Treprostinil | Synephrine may decrease the antihypertensive activities of Treprostinil. |
| Amlodipine | Synephrine may decrease the antihypertensive activities of Amlodipine. |
| Nimodipine | Synephrine may decrease the antihypertensive activities of Nimodipine. |
| Nisoldipine | Synephrine may decrease the antihypertensive activities of Nisoldipine. |
| Bendroflumethiazide | Synephrine may decrease the antihypertensive activities of Bendroflumethiazide. |
| Fosinopril | Synephrine may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Synephrine may decrease the antihypertensive activities of Trandolapril. |
| Metolazone | Synephrine may decrease the antihypertensive activities of Metolazone. |
| Lercanidipine | Synephrine may decrease the antihypertensive activities of Lercanidipine. |
| Benazepril | Synephrine may decrease the antihypertensive activities of Benazepril. |
| Bosentan | Synephrine may decrease the antihypertensive activities of Bosentan. |
| Enalapril | Synephrine may decrease the antihypertensive activities of Enalapril. |
| Cyclothiazide | Synephrine may decrease the antihypertensive activities of Cyclothiazide. |
| Candoxatril | Synephrine may decrease the antihypertensive activities of Candoxatril. |
| Mecamylamine | Synephrine may decrease the antihypertensive activities of Mecamylamine. |
| Losartan | Synephrine may decrease the antihypertensive activities of Losartan. |
| Moexipril | Synephrine may decrease the antihypertensive activities of Moexipril. |
| Eplerenone | Synephrine may decrease the antihypertensive activities of Eplerenone. |
| Lisinopril | Synephrine may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Synephrine may decrease the antihypertensive activities of Nitroglycerin. |
| Metyrosine | Synephrine may decrease the antihypertensive activities of Metyrosine. |
| Hydroflumethiazide | Synephrine may decrease the antihypertensive activities of Hydroflumethiazide. |
| Cryptenamine | Synephrine may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Synephrine may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Synephrine may decrease the antihypertensive activities of Candesartan cilexetil. |
| Fenoldopam | Synephrine may decrease the antihypertensive activities of Fenoldopam. |
| Indapamide | Synephrine may decrease the antihypertensive activities of Indapamide. |
| Tadalafil | Synephrine may decrease the antihypertensive activities of Tadalafil. |
| Eprosartan | Synephrine may decrease the antihypertensive activities of Eprosartan. |
| Chlorothiazide | Synephrine may decrease the antihypertensive activities of Chlorothiazide. |
| Quinapril | Synephrine may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Synephrine may decrease the antihypertensive activities of Telmisartan. |
| Methyldopa | Synephrine may decrease the antihypertensive activities of Methyldopa. |
| Hydrochlorothiazide | Synephrine may decrease the antihypertensive activities of Hydrochlorothiazide. |
| Trichlormethiazide | Synephrine may decrease the antihypertensive activities of Trichlormethiazide. |
| Irbesartan | Synephrine may decrease the antihypertensive activities of Irbesartan. |
| Nitrendipine | Synephrine may decrease the antihypertensive activities of Nitrendipine. |
| Deserpidine | Synephrine may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Synephrine may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Synephrine may decrease the antihypertensive activities of Trimethaphan. |
| Diazoxide | Synephrine may decrease the antihypertensive activities of Diazoxide. |
| Captopril | Synephrine may decrease the antihypertensive activities of Captopril. |
| Epoprostenol | Synephrine may decrease the antihypertensive activities of Epoprostenol. |
| Bepridil | Synephrine may decrease the antihypertensive activities of Bepridil. |
| Hydralazine | Synephrine may decrease the antihypertensive activities of Hydralazine. |
| Polythiazide | Synephrine may decrease the antihypertensive activities of Polythiazide. |
| Cilazapril | Synephrine may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Synephrine may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Synephrine may decrease the antihypertensive activities of Spirapril. |
| Mibefradil | Synephrine may decrease the antihypertensive activities of Mibefradil. |
| Tienilic acid | Synephrine may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Synephrine may decrease the antihypertensive activities of Debrisoquine. |
| Sitaxentan | Synephrine may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Synephrine may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Synephrine may decrease the antihypertensive activities of Diethylnorspermine. |
| Nilvadipine | Synephrine may decrease the antihypertensive activities of Nilvadipine. |
| Pinacidil | Synephrine may decrease the antihypertensive activities of Pinacidil. |
| Temocapril | Synephrine may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Synephrine may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Synephrine may decrease the antihypertensive activities of Macitentan. |
| Hexamethonium | Synephrine may decrease the antihypertensive activities of Hexamethonium. |
| Aliskiren | Synephrine may decrease the antihypertensive activities of Aliskiren. |
| Nicorandil | Synephrine may decrease the antihypertensive activities of Nicorandil. |
| Efonidipine | Synephrine may decrease the antihypertensive activities of Efonidipine. |
| Lacidipine | Synephrine may decrease the antihypertensive activities of Lacidipine. |
| Manidipine | Synephrine may decrease the antihypertensive activities of Manidipine. |
| Rauwolfia serpentina root | Synephrine may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Synephrine may decrease the antihypertensive activities of Enalaprilat. |
| Selexipag | Synephrine may decrease the antihypertensive activities of Selexipag. |
| Angiotensin 1-7 | Synephrine may decrease the antihypertensive activities of Angiotensin 1-7. |
| Imidapril | Synephrine may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Synephrine may decrease the antihypertensive activities of BQ-123. |
| Tetrahydropalmatine | Synephrine may decrease the antihypertensive activities of Tetrahydropalmatine. |
| Cicletanine | Synephrine may decrease the antihypertensive activities of Cicletanine. |
| Dihydralazine | Synephrine may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Synephrine may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Synephrine may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Synephrine may decrease the antihypertensive activities of Delapril. |
| Vincamine | Synephrine may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Synephrine may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Synephrine may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Synephrine may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Synephrine may decrease the antihypertensive activities of Endralazine. |
| Cadralazine | Synephrine may decrease the antihypertensive activities of Cadralazine. |
| Cyclopenthiazide | Synephrine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Bietaserpine | Synephrine may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Synephrine may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Synephrine may decrease the antihypertensive activities of Methoserpidine. |
| Guanoclor | Synephrine may decrease the antihypertensive activities of Guanoclor. |