Peringatan Keamanan

May cause burns or frostbites in case of eye or skin contact with rapidly expanding gas. Oxygen therapy can induce hypercapnic respiratory failure in patients with respiratory diseases and musculoskeletal diseases in upper airways. Sudden cessation of oxygen supplementation in these patients can further lead to rebound hypoxaemia. In patients with mild or moderate strokes, hyperoxaemia may cause absorption atelectasis or myocardial infarction. Oxygen content should be monitored following the administration to verify therapeutic benefit.

Oxygen

DB09140

small molecule approved vet_approved

Deskripsi

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.

Struktur Molekul 2D

Berat 31.9988
Wujud gas

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) Approximately 122.24 seconds
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Exhalation

Interaksi Obat

0 Data
Tidak ada data.

Target Protein

Cytochrome c oxidase subunit 1 MT-CO1
NADPH oxidase 1 NOX1

Referensi & Sumber

Artikel (PubMed)
  • PMID: 24642336
    Heyboer M 3rd, Milovanova TN, Wojcik S, Grant W, Chin M, Hardy KR, Lambert DS, Logue C, Thom SR: CD34+/CD45-dim stem cell mobilization by hyperbaric oxygen - changes with oxygen dosage. Stem Cell Res. 2014 May;12(3):638-45. doi: 10.1016/j.scr.2014.02.005. Epub 2014 Feb 28.
  • PMID: 10846047
    Prabhakar NR: Oxygen sensing by the carotid body chemoreceptors. J Appl Physiol (1985). 2000 Jun;88(6):2287-95.
  • PMID: 25206416
    Feng Z, Liu J, Ju R: Hyperbaric oxygen treatment promotes neural stem cell proliferation in the subventricular zone of neonatal rats with hypoxic-ischemic brain damage. Neural Regen Res. 2013 May 5;8(13):1220-7. doi: 10.3969/j.issn.1673-5374.2013.13.007.
  • PMID: 26764048
    Lopez-Barneo J, Gonzalez-Rodriguez P, Gao L, Fernandez-Aguera MC, Pardal R, Ortega-Saenz P: Oxygen sensing by the carotid body: mechanisms and role in adaptation to hypoxia. Am J Physiol Cell Physiol. 2016 Apr 15;310(8):C629-42. doi: 10.1152/ajpcell.00265.2015. Epub 2016 Jan 13.
  • PMID: 22146102
    Liu W, Khatibi N, Sridharan A, Zhang JH: Application of medical gases in the field of neurobiology. Med Gas Res. 2011 Jun 27;1(1):13. doi: 10.1186/2045-9912-1-13.

Contoh Produk & Brand

Produk: 1421 • International brands: 0
Produk
  • 40% Oxygen/Nitrogen Mix
    Gas • 400 mL/1L • Respiratory (inhalation) • US • Approved
  • Air
    Gas • - • Respiratory (inhalation) • US
  • Air
    Gas • - • Respiratory (inhalation) • US
  • Air
    Gas • 20.9 L/100L • Respiratory (inhalation) • US
  • Air
    Gas • 195 mL/1000mL • Respiratory (inhalation) • US
  • Air
    Gas • 21 L/1L • Respiratory (inhalation) • US • Approved
  • Air
    Gas • 210 mL/1L • Respiratory (inhalation) • US
  • Air
    Gas • 210 mL/1L • Respiratory (inhalation) • US
Menampilkan 8 dari 1421 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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