Cupric Chloride

Peringatan Keamanan

LD50 not available
Copper toxicity can produce prostration, behavior change, diarrhea, progressive marasmus, hypotonia, photophobia and peripheral edema. Such symptoms have been reported with a serum copper level of 286 mcg/dl. Copper toxicity can also result in hemolysis and liver toxicity, including hepatic necrosis which may be fatal. D-penicillamine has been reported effective as an antidote.

Peta Jejaring Molekuler

Obat Target Gen Interaksi Enzim Transporter Carrier

Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

1. Pendahuluan & Konsep

Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).

2. Sumber Data (Validasi)

Data Obat: Diekstraksi dari elemen drugbank-id dan name pada skema XML DrugBank.
Target Protein: Diambil dari elemen targets/target yang memuat polipeptida sasaran.
Genetik: Disinkronisasi dari sub-elemen gene-name dan varian snp-effects.
Genetik: Jumlah titik node dibatasi pada maksimal 10 (Slice=10) interaksi untuk menghindari tumpukan data.

3. Algoritma Visualisasi

Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.

4. Legenda Visual

Obat Utama (Pusat Analisis)

Target Protein (Mekanisme)

Gen (Faktor Genetik)

Metode ini mendukung analisis Precision Medicine dan evaluasi risiko Drug-Drug Interaction (DDI).

Profil Farmakokinetik

Waktu Paruh (Half-Life) -

Volume Distribusi Copper is distributed to all tissues with the highest concentrations in liver, heart, brain, kidneys and muscle. Intracellular copper is predominantly metallothionein-bound. Reported copper in the lungs, liver, kidney, blood, bile and stomach (33.7, 35.1, 41.4, 13.8, 2.8, and 2988 µg/g wet weight respectively)

Klirens (Clearance) -

Absorpsi

Mean copper absorption of 57 percent (range 40 to 70 per cent) following oral administration of 0.4 - 4.5 mg copper (as copper acetate) to four volunteers. An early human study suggested a maximum blood copper concentration was reached some two hours after oral copper chloride administration (1.5 - 12 mg copper)

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Renal

Interaksi Obat

0 Data

Tidak ada data.

Target Protein

Vitamin K-dependent protein C PROC

Cystatin-B CSTB

Referensi & Sumber

Link

Contoh Produk & Brand

Produk: 10 • International brands: 0

Produk

Addnutriv

Solution • - • Intravenous • Canada • Approved
Copper

Injection, solution • 0.4 mg/1mL • Intravenous • US • Approved
Cupric Chloride

Injection, solution • 0.4 mg/1mL • Intravenous • US • Generic • Approved
Cupric Chloride

Injection • 0.4 mg/1mL • Intravenous • US • Generic • Approved
Cupric Chloride

Injection, solution • 0.4 mg/1mL • Intravenous • US • Generic • Approved
Cupric Chloride

Injection, solution • 0.4 mg/1mL • Intravenous • US • Generic • Approved
Peditrace

Injection, solution • - • Intravenous • US
Trace Elements for Injection - Liq IV

Liquid • - • Intravenous • Canada • Approved

Menampilkan 8 dari 10 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.