Peringatan Keamanan

LD50 (dog): Intravenous 176 mg/kg.

Potassium citrate

DB09125

small molecule approved investigational vet_approved

Deskripsi

Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent.
Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. Potassium Citrate is indicated also for the management of Hypocitraturic calcium oxalate nephrolithiasis.

Struktur Molekul 2D

Berat 306.394
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Potassium Citrate is absorbed and the citrate is metabolised to bicarbonate.

Rute Eliminasi

Urinary; less than 5% unchanged.

Interaksi Makanan

1 Data
  • 1. Take with food. Take potassium citrate within 30 minutes of eating to limit gastrointestinal irritation.

Interaksi Obat

905 Data
Dabigatran etexilate Potassium citrate may increase the excretion rate of Dabigatran etexilate which could result in a lower serum level and potentially a reduction in efficacy.
Dehydrocholic acid The risk or severity of dehydration can be increased when Potassium citrate is combined with Dehydrocholic acid.
Edoxaban Potassium citrate may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy.
Rivaroxaban Potassium citrate may increase the excretion rate of Rivaroxaban which could result in a lower serum level and potentially a reduction in efficacy.
Ifosfamide Potassium citrate may increase the excretion rate of Ifosfamide which could result in a lower serum level and potentially a reduction in efficacy.
Quinidine Potassium citrate may increase the excretion rate of Quinidine which could result in a lower serum level and potentially a reduction in efficacy.
Pentoxifylline Potassium citrate may increase the excretion rate of Pentoxifylline which could result in a lower serum level and potentially a reduction in efficacy.
Aluminum hydroxide Potassium citrate can cause an increase in the absorption of Aluminum hydroxide resulting in an increased serum concentration and potentially a worsening of adverse effects.
Levocarnitine Potassium citrate may increase the excretion rate of Levocarnitine which could result in a lower serum level and potentially a reduction in efficacy.
Conjugated estrogens Potassium citrate may increase the excretion rate of Conjugated estrogens which could result in a lower serum level and potentially a reduction in efficacy.
Estrone sulfate Potassium citrate may increase the excretion rate of Estrone sulfate which could result in a lower serum level and potentially a reduction in efficacy.
Synthetic Conjugated Estrogens, A Potassium citrate may increase the excretion rate of Synthetic Conjugated Estrogens, A which could result in a lower serum level and potentially a reduction in efficacy.
Synthetic Conjugated Estrogens, B Potassium citrate may increase the excretion rate of Synthetic Conjugated Estrogens, B which could result in a lower serum level and potentially a reduction in efficacy.
Estradiol acetate Potassium citrate may increase the excretion rate of Estradiol acetate which could result in a lower serum level and potentially a reduction in efficacy.
Estradiol cypionate Potassium citrate may increase the excretion rate of Estradiol cypionate which could result in a lower serum level and potentially a reduction in efficacy.
Estradiol valerate Potassium citrate may increase the excretion rate of Estradiol valerate which could result in a lower serum level and potentially a reduction in efficacy.
Icosapent Potassium citrate may increase the hyperkalemic activities of Icosapent.
Mesalazine Potassium citrate may increase the hyperkalemic activities of Mesalazine.
Nabumetone Potassium citrate may increase the hyperkalemic activities of Nabumetone.
Ketorolac Potassium citrate may increase the hyperkalemic activities of Ketorolac.
Tenoxicam Potassium citrate may increase the hyperkalemic activities of Tenoxicam.
Celecoxib Potassium citrate may increase the hyperkalemic activities of Celecoxib.
Tolmetin Potassium citrate may increase the hyperkalemic activities of Tolmetin.
Rofecoxib Potassium citrate may increase the hyperkalemic activities of Rofecoxib.
Piroxicam Potassium citrate may increase the hyperkalemic activities of Piroxicam.
Fenoprofen Potassium citrate may increase the hyperkalemic activities of Fenoprofen.
Valdecoxib Potassium citrate may increase the hyperkalemic activities of Valdecoxib.
Diclofenac Potassium citrate may increase the hyperkalemic activities of Diclofenac.
Sulindac Potassium citrate may increase the hyperkalemic activities of Sulindac.
Flurbiprofen Potassium citrate may increase the hyperkalemic activities of Flurbiprofen.
Etodolac Potassium citrate may increase the hyperkalemic activities of Etodolac.
Mefenamic acid Potassium citrate may increase the hyperkalemic activities of Mefenamic acid.
Naproxen Potassium citrate may increase the hyperkalemic activities of Naproxen.
Sulfasalazine Potassium citrate may increase the hyperkalemic activities of Sulfasalazine.
Phenylbutazone Potassium citrate may increase the hyperkalemic activities of Phenylbutazone.
Carprofen Potassium citrate may increase the hyperkalemic activities of Carprofen.
Diflunisal Potassium citrate may increase the hyperkalemic activities of Diflunisal.
Salicylic acid Potassium citrate may increase the hyperkalemic activities of Salicylic acid.
Meclofenamic acid Potassium citrate may increase the hyperkalemic activities of Meclofenamic acid.
Oxaprozin Potassium citrate may increase the hyperkalemic activities of Oxaprozin.
Ketoprofen Potassium citrate may increase the hyperkalemic activities of Ketoprofen.
Balsalazide Potassium citrate may increase the hyperkalemic activities of Balsalazide.
Lumiracoxib Potassium citrate may increase the hyperkalemic activities of Lumiracoxib.
Magnesium salicylate Potassium citrate may increase the hyperkalemic activities of Magnesium salicylate.
Salsalate Potassium citrate may increase the hyperkalemic activities of Salsalate.
Choline magnesium trisalicylate Potassium citrate may increase the hyperkalemic activities of Choline magnesium trisalicylate.
Antrafenine Potassium citrate may increase the hyperkalemic activities of Antrafenine.
Aminophenazone Potassium citrate may increase the hyperkalemic activities of Aminophenazone.
Antipyrine Potassium citrate may increase the hyperkalemic activities of Antipyrine.
Tiaprofenic acid Potassium citrate may increase the hyperkalemic activities of Tiaprofenic acid.
Etoricoxib Potassium citrate may increase the hyperkalemic activities of Etoricoxib.
Oxyphenbutazone Potassium citrate may increase the hyperkalemic activities of Oxyphenbutazone.
Benoxaprofen Potassium citrate may increase the hyperkalemic activities of Benoxaprofen.
Metamizole Potassium citrate may increase the hyperkalemic activities of Metamizole.
Zomepirac Potassium citrate may increase the hyperkalemic activities of Zomepirac.
Cimicoxib Potassium citrate may increase the hyperkalemic activities of Cimicoxib.
Lornoxicam Potassium citrate may increase the hyperkalemic activities of Lornoxicam.
Aceclofenac Potassium citrate may increase the hyperkalemic activities of Aceclofenac.
Zaltoprofen Potassium citrate may increase the hyperkalemic activities of Zaltoprofen.
Azapropazone Potassium citrate may increase the hyperkalemic activities of Azapropazone.
Parecoxib Potassium citrate may increase the hyperkalemic activities of Parecoxib.
Salicylamide Potassium citrate may increase the hyperkalemic activities of Salicylamide.
Kebuzone Potassium citrate may increase the hyperkalemic activities of Kebuzone.
Isoxicam Potassium citrate may increase the hyperkalemic activities of Isoxicam.
Indoprofen Potassium citrate may increase the hyperkalemic activities of Indoprofen.
Ibuproxam Potassium citrate may increase the hyperkalemic activities of Ibuproxam.
Floctafenine Potassium citrate may increase the hyperkalemic activities of Floctafenine.
Fenbufen Potassium citrate may increase the hyperkalemic activities of Fenbufen.
Etofenamate Potassium citrate may increase the hyperkalemic activities of Etofenamate.
Epirizole Potassium citrate may increase the hyperkalemic activities of Epirizole.
Benzydamine Potassium citrate may increase the hyperkalemic activities of Benzydamine.
Dexketoprofen Potassium citrate may increase the hyperkalemic activities of Dexketoprofen.
Droxicam Potassium citrate may increase the hyperkalemic activities of Droxicam.
Tolfenamic acid Potassium citrate may increase the hyperkalemic activities of Tolfenamic acid.
Firocoxib Potassium citrate may increase the hyperkalemic activities of Firocoxib.
Clonixin Potassium citrate may increase the hyperkalemic activities of Clonixin.
Morniflumate Potassium citrate may increase the hyperkalemic activities of Morniflumate.
Propacetamol Potassium citrate may increase the hyperkalemic activities of Propacetamol.
Talniflumate Potassium citrate may increase the hyperkalemic activities of Talniflumate.
Robenacoxib Potassium citrate may increase the hyperkalemic activities of Robenacoxib.
Tepoxalin Potassium citrate may increase the hyperkalemic activities of Tepoxalin.
Flunixin Potassium citrate may increase the hyperkalemic activities of Flunixin.
Tinoridine Potassium citrate may increase the hyperkalemic activities of Tinoridine.
Alclofenac Potassium citrate may increase the hyperkalemic activities of Alclofenac.
Fentiazac Potassium citrate may increase the hyperkalemic activities of Fentiazac.
Suxibuzone Potassium citrate may increase the hyperkalemic activities of Suxibuzone.
Bumadizone Potassium citrate may increase the hyperkalemic activities of Bumadizone.
Alminoprofen Potassium citrate may increase the hyperkalemic activities of Alminoprofen.
Difenpiramide Potassium citrate may increase the hyperkalemic activities of Difenpiramide.
Nifenazone Potassium citrate may increase the hyperkalemic activities of Nifenazone.
Lonazolac Potassium citrate may increase the hyperkalemic activities of Lonazolac.
Tenidap Potassium citrate may increase the hyperkalemic activities of Tenidap.
Propyphenazone Potassium citrate may increase the hyperkalemic activities of Propyphenazone.
Proglumetacin Potassium citrate may increase the hyperkalemic activities of Proglumetacin.
Guacetisal Potassium citrate may increase the hyperkalemic activities of Guacetisal.
Ethenzamide Potassium citrate may increase the hyperkalemic activities of Ethenzamide.
Carbaspirin calcium Potassium citrate may increase the hyperkalemic activities of Carbaspirin calcium.
Mofebutazone Potassium citrate may increase the hyperkalemic activities of Mofebutazone.
Proquazone Potassium citrate may increase the hyperkalemic activities of Proquazone.
Benorilate Potassium citrate may increase the hyperkalemic activities of Benorilate.

Referensi & Sumber

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