Chlortetracycline is a tetracycline antibiotic, and historically the first member of this class to be identified. It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow. He discovered that this antibiotic was the product of an actinomycete strain he cultured and obtained from a soil sample from a field in Missouri. The organism was named Streptomyces aureofaciens due to its gold-hued color.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Methoxyflurane | The risk or severity of renal failure can be increased when Methoxyflurane is combined with Chlortetracycline. |
| Magnesium | Magnesium can cause a decrease in the absorption of Chlortetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Vibrio cholerae CVD 103-HgR strain live antigen | The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Chlortetracycline. |
| Didanosine | Didanosine can cause a decrease in the absorption of Chlortetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Collagenase clostridium histolyticum | The therapeutic efficacy of Collagenase clostridium histolyticum can be decreased when used in combination with Chlortetracycline. |
| Acetylcysteine | The therapeutic efficacy of Acetylcysteine can be decreased when used in combination with Chlortetracycline. |
| Estetrol | The therapeutic efficacy of Estetrol can be decreased when used in combination with Chlortetracycline. |
| Palovarotene | The risk or severity of pseudotumor cerebri can be increased when Chlortetracycline is combined with Palovarotene. |
| Lidocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Lidocaine. |
| Ropivacaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Ropivacaine. |
| Bupivacaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Bupivacaine. |
| Cinchocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Cinchocaine. |
| Dyclonine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Dyclonine. |
| Procaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Procaine. |
| Prilocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Prilocaine. |
| Proparacaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Proparacaine. |
| Meloxicam | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Meloxicam. |
| Oxybuprocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Oxybuprocaine. |
| Cocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Cocaine. |
| Mepivacaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Mepivacaine. |
| Levobupivacaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Levobupivacaine. |
| Diphenhydramine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Diphenhydramine. |
| Benzocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Benzocaine. |
| Chloroprocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Chloroprocaine. |
| Phenol | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Phenol. |
| Tetrodotoxin | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Tetrodotoxin. |
| Benzyl alcohol | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Benzyl alcohol. |
| Capsaicin | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Capsaicin. |
| Etidocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Etidocaine. |
| Articaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Articaine. |
| Tetracaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Tetracaine. |
| Propoxycaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Propoxycaine. |
| Pramocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Pramocaine. |
| Butamben | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Butamben. |
| Butacaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Butacaine. |
| Oxetacaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Oxetacaine. |
| Ethyl chloride | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Ethyl chloride. |
| Butanilicaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Butanilicaine. |
| Metabutethamine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Metabutethamine. |
| Quinisocaine | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Quinisocaine. |
| Cisatracurium | Chlortetracycline may increase the neuromuscular blocking activities of Cisatracurium. |
| Ambroxol | The risk or severity of methemoglobinemia can be increased when Chlortetracycline is combined with Ambroxol. |
| Fecal microbiota | The therapeutic efficacy of Fecal microbiota can be decreased when used in combination with Chlortetracycline. |