Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended withdrawing all benfluorex containing medicines on 18 December 2009. This recommendation was based on the risks (especially fenfluramine-like cardiovascular side-effects) outweighing the benefits.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Pegvisomant | The risk or severity of hypoglycemia can be increased when Pegvisomant is combined with Benfluorex. |
| Lipoic acid | The risk or severity of hypoglycemia can be increased when Lipoic acid is combined with Benfluorex. |
| Moxifloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Moxifloxacin. |
| Grepafloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Grepafloxacin. |
| Enoxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Enoxacin. |
| Pefloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Pefloxacin. |
| Ciprofloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Ciprofloxacin. |
| Trovafloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Trovafloxacin. |
| Nalidixic acid | The therapeutic efficacy of Benfluorex can be increased when used in combination with Nalidixic acid. |
| Rosoxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Rosoxacin. |
| Cinoxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Cinoxacin. |
| Lomefloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Lomefloxacin. |
| Gatifloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Gatifloxacin. |
| Norfloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Norfloxacin. |
| Levofloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Levofloxacin. |
| Gemifloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Gemifloxacin. |
| Ofloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Ofloxacin. |
| Sparfloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Sparfloxacin. |
| Temafloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Temafloxacin. |
| Fleroxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Fleroxacin. |
| Technetium Tc-99m ciprofloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Technetium Tc-99m ciprofloxacin. |
| Garenoxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Garenoxacin. |
| Nemonoxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Nemonoxacin. |
| Flumequine | The therapeutic efficacy of Benfluorex can be increased when used in combination with Flumequine. |
| Enrofloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Enrofloxacin. |
| Orbifloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Orbifloxacin. |
| Sarafloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Sarafloxacin. |
| Difloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Difloxacin. |
| Pazufloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Pazufloxacin. |
| Prulifloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Prulifloxacin. |
| Delafloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Delafloxacin. |
| Sitafloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Sitafloxacin. |
| Oxolinic acid | The therapeutic efficacy of Benfluorex can be increased when used in combination with Oxolinic acid. |
| Rufloxacin | The therapeutic efficacy of Benfluorex can be increased when used in combination with Rufloxacin. |
| Pipemidic acid | The therapeutic efficacy of Benfluorex can be increased when used in combination with Pipemidic acid. |
| Methyclothiazide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Methyclothiazide. |
| Chlorthalidone | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Chlorthalidone. |
| Bendroflumethiazide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Bendroflumethiazide. |
| Metolazone | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Metolazone. |
| Benzthiazide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Benzthiazide. |
| Hydroflumethiazide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Hydroflumethiazide. |
| Indapamide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Indapamide. |
| Chlorothiazide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Chlorothiazide. |
| Hydrochlorothiazide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Hydrochlorothiazide. |
| Trichlormethiazide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Trichlormethiazide. |
| Polythiazide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Polythiazide. |
| Quinethazone | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Quinethazone. |
| Cyclopenthiazide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Cyclopenthiazide. |
| Epitizide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Epitizide. |
| Amitriptyline | Amitriptyline may decrease the hypoglycemic activities of Benfluorex. |
| Protriptyline | Protriptyline may decrease the hypoglycemic activities of Benfluorex. |
| Imipramine | Imipramine may decrease the hypoglycemic activities of Benfluorex. |
| Nortriptyline | Nortriptyline may decrease the hypoglycemic activities of Benfluorex. |
| Amoxapine | Amoxapine may decrease the hypoglycemic activities of Benfluorex. |
| Trimipramine | Trimipramine may decrease the hypoglycemic activities of Benfluorex. |
| Doxepin | Doxepin may decrease the hypoglycemic activities of Benfluorex. |
| Desipramine | Desipramine may decrease the hypoglycemic activities of Benfluorex. |
| Clomipramine | Clomipramine may decrease the hypoglycemic activities of Benfluorex. |
| Amineptine | Amineptine may decrease the hypoglycemic activities of Benfluorex. |
| Dimetacrine | Dimetacrine may decrease the hypoglycemic activities of Benfluorex. |
| Butriptyline | Butriptyline may decrease the hypoglycemic activities of Benfluorex. |
| Dosulepin | Dosulepin may decrease the hypoglycemic activities of Benfluorex. |
| Tianeptine | Tianeptine may decrease the hypoglycemic activities of Benfluorex. |
| Oxaprotiline | Oxaprotiline may decrease the hypoglycemic activities of Benfluorex. |
| Opipramol | Opipramol may decrease the hypoglycemic activities of Benfluorex. |
| Amitriptylinoxide | Amitriptylinoxide may decrease the hypoglycemic activities of Benfluorex. |
| Dibenzepin | Dibenzepin may decrease the hypoglycemic activities of Benfluorex. |
| Quinupramine | Quinupramine may decrease the hypoglycemic activities of Benfluorex. |
| Melitracen | Melitracen may decrease the hypoglycemic activities of Benfluorex. |
| Lofepramine | Lofepramine may decrease the hypoglycemic activities of Benfluorex. |
| Iprindole | Iprindole may decrease the hypoglycemic activities of Benfluorex. |
| Imipramine oxide | Imipramine oxide may decrease the hypoglycemic activities of Benfluorex. |
| Dapagliflozin | Dapagliflozin may increase the hypoglycemic activities of Benfluorex. |
| Canagliflozin | Canagliflozin may increase the hypoglycemic activities of Benfluorex. |
| Leuprolide | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Leuprolide. |
| Goserelin | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Goserelin. |
| Nelfinavir | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Nelfinavir. |
| Indinavir | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Indinavir. |
| Ziprasidone | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Ziprasidone. |
| Etonogestrel | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Etonogestrel. |
| Desogestrel | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Desogestrel. |
| Olanzapine | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Olanzapine. |
| Megestrol acetate | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Megestrol acetate. |
| Clozapine | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Clozapine. |
| Levonorgestrel | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Levonorgestrel. |
| Progesterone | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Progesterone. |
| Chlorpromazine | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Chlorpromazine. |
| Haloperidol | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Haloperidol. |
| Ritonavir | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Ritonavir. |
| Piperazine | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Piperazine. |
| Medroxyprogesterone acetate | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Medroxyprogesterone acetate. |
| Niacin | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Niacin. |
| Epinephrine | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Epinephrine. |
| Norethisterone | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Norethisterone. |
| Risperidone | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Risperidone. |
| Pentamidine | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Pentamidine. |
| Ethynodiol diacetate | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Ethynodiol diacetate. |
| Pseudoephedrine | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Pseudoephedrine. |
| Tacrolimus | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Tacrolimus. |
| Sirolimus | The therapeutic efficacy of Benfluorex can be decreased when used in combination with Sirolimus. |