Articaine

DB09009

small molecule approved

Deskripsi

Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.

Struktur Molekul 2D

Berat 284.374
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1694 Data
Buprenorphine Articaine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Articaine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Articaine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Articaine.
Hydrocodone Articaine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Articaine.
Magnesium sulfate The therapeutic efficacy of Articaine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Articaine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Articaine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Articaine.
Mirtazapine Articaine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Articaine.
Orphenadrine Articaine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Articaine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Articaine.
Pramipexole Articaine may increase the sedative activities of Pramipexole.
Ropinirole Articaine may increase the sedative activities of Ropinirole.
Rotigotine Articaine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Articaine.
Sodium oxybate The risk or severity of CNS depression can be increased when Articaine is combined with Sodium oxybate.
Suvorexant Articaine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Articaine.
Thalidomide Articaine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Articaine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Prilocaine The risk or severity of methemoglobinemia can be increased when Articaine is combined with Prilocaine.
Hyaluronidase (ovine) Hyaluronidase (ovine) can cause an increase in the absorption of Articaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Hyaluronidase (human recombinant) Hyaluronidase (human recombinant) can cause an increase in the absorption of Articaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Hyaluronidase Hyaluronidase can cause an increase in the absorption of Articaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Articaine.
Ethanol Articaine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Articaine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Articaine.
Fluvoxamine The risk or severity of adverse effects can be increased when Articaine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Articaine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Articaine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Articaine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Articaine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Articaine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Articaine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Articaine is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Articaine is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Articaine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Articaine is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Articaine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Articaine is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Articaine is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Articaine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Articaine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Articaine is combined with Alaproclate.
Dapsone The risk or severity of methemoglobinemia can be increased when Dapsone is combined with Articaine.
Technetium Tc-99m tilmanocept Articaine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Articaine.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Articaine.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Articaine.
Promazine The risk or severity of CNS depression can be increased when Promazine is combined with Articaine.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Articaine.
Imipramine The risk or severity of CNS depression can be increased when Imipramine is combined with Articaine.
Chlorpromazine The risk or severity of CNS depression can be increased when Chlorpromazine is combined with Articaine.
Gallamine triethiodide The risk or severity of CNS depression can be increased when Gallamine triethiodide is combined with Articaine.
Triflupromazine The risk or severity of CNS depression can be increased when Triflupromazine is combined with Articaine.
Nortriptyline The risk or severity of CNS depression can be increased when Nortriptyline is combined with Articaine.
Amoxapine The risk or severity of CNS depression can be increased when Amoxapine is combined with Articaine.
Lamotrigine The risk or severity of methemoglobinemia can be increased when Lamotrigine is combined with Articaine.
Rocuronium The risk or severity of CNS depression can be increased when Rocuronium is combined with Articaine.
Scopolamine The risk or severity of CNS depression can be increased when Scopolamine is combined with Articaine.
Clidinium The risk or severity of CNS depression can be increased when Clidinium is combined with Articaine.
Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with Articaine.
Brompheniramine The risk or severity of CNS depression can be increased when Brompheniramine is combined with Articaine.
Flupentixol The risk or severity of CNS depression can be increased when Flupentixol is combined with Articaine.
Cocaine The risk or severity of methemoglobinemia can be increased when Cocaine is combined with Articaine.
Quinidine The risk or severity of methemoglobinemia can be increased when Quinidine is combined with Articaine.
Maprotiline The risk or severity of CNS depression can be increased when Maprotiline is combined with Articaine.
Promethazine The risk or severity of CNS depression can be increased when Promethazine is combined with Articaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when Diphenhydramine is combined with Articaine.
Doxacurium The risk or severity of CNS depression can be increased when Doxacurium is combined with Articaine.
Doxepin The risk or severity of CNS depression can be increased when Doxepin is combined with Articaine.
Desipramine The risk or severity of CNS depression can be increased when Desipramine is combined with Articaine.
Quetiapine The risk or severity of CNS depression can be increased when Quetiapine is combined with Articaine.
Mivacurium The risk or severity of CNS depression can be increased when Mivacurium is combined with Articaine.
Aripiprazole The risk or severity of CNS depression can be increased when Aripiprazole is combined with Articaine.
Chlorprothixene The risk or severity of CNS depression can be increased when Chlorprothixene is combined with Articaine.
Metocurine The risk or severity of CNS depression can be increased when Metocurine is combined with Articaine.
Pancuronium The risk or severity of CNS depression can be increased when Pancuronium is combined with Articaine.
Pipecuronium The risk or severity of CNS depression can be increased when Pipecuronium is combined with Articaine.
Rapacuronium The risk or severity of CNS depression can be increased when Rapacuronium is combined with Articaine.
Pizotifen The risk or severity of CNS depression can be increased when Pizotifen is combined with Articaine.
Benactyzine The risk or severity of CNS depression can be increased when Articaine is combined with Benactyzine.
Dosulepin The risk or severity of CNS depression can be increased when Articaine is combined with Dosulepin.
Emepronium The risk or severity of CNS depression can be increased when Articaine is combined with Emepronium.
Insulin human The therapeutic efficacy of Insulin human can be decreased when used in combination with Articaine.
Insulin lispro The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Articaine.
Insulin glargine The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Articaine.
Insulin pork The therapeutic efficacy of Insulin pork can be decreased when used in combination with Articaine.
Troglitazone The therapeutic efficacy of Troglitazone can be decreased when used in combination with Articaine.
Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with Articaine.
Sulfisoxazole The risk or severity of methemoglobinemia can be increased when Sulfisoxazole is combined with Articaine.
Disopyramide The therapeutic efficacy of Disopyramide can be decreased when used in combination with Articaine.
Acarbose The therapeutic efficacy of Acarbose can be decreased when used in combination with Articaine.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be decreased when used in combination with Articaine.
Acetohexamide The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Articaine.

Target Protein

Voltage-gated sodium channel alpha subunit SCN1A

Referensi & Sumber

Synthesis reference: U.S. Patent 3,910,924.

Contoh Produk & Brand

Produk: 46 • International brands: 3
Produk
  • 4% Astracaine Dental With Epinephrine 1:200,000 (0.005mg/ml)
    Solution • - • Infiltration • Canada • Approved
  • 4% Astracaine Dental With Epinephrine 1:200,000 (0.005mg/ml)
    Solution • - • Infiltration • Canada • Approved
  • 4% Astracaine Dental With Epinephrine Forte 1:100,000 (0.01mg/ml)
    Solution • - • Infiltration • Canada • Approved
  • 4% Astracaine Dental With Epinephrine Forte 1:100,000 (0.01mg/ml)
    Solution • - • Infiltration • Canada • Approved
  • Articadent
    Injection, solution • - • Infiltration; Submucosal • US • Approved
  • Articadent
    Injection, solution • - • Infiltration; Submucosal • US • Approved
  • Articaine
    Injection, solution • - • Subcutaneous • US • Approved
  • Articaine
    Injection, solution • - • Subcutaneous • US • Approved
Menampilkan 8 dari 46 produk.
International Brands
  • Septanest
  • Septocaine
  • Ultracaine

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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