Dimetacrine may induce severe cardiac toxicity in overdose. This property is unique among the tricyclic antidepressants.
Dimetacrine is also known as dimethacrine or acripamine. It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in Europe for the treatment of depression. Dimetacrine is no longer used in Japan.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Valsartan | Dimetacrine may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Dimetacrine may decrease the antihypertensive activities of Ramipril. |
| Esmolol | Dimetacrine may decrease the antihypertensive activities of Esmolol. |
| Betaxolol | Dimetacrine may decrease the antihypertensive activities of Betaxolol. |
| Remikiren | Dimetacrine may decrease the antihypertensive activities of Remikiren. |
| Guanadrel | Dimetacrine may decrease the antihypertensive activities of Guanadrel. |
| Olmesartan | Dimetacrine may decrease the antihypertensive activities of Olmesartan. |
| Atenolol | Dimetacrine may decrease the antihypertensive activities of Atenolol. |
| Diltiazem | Dimetacrine may decrease the antihypertensive activities of Diltiazem. |
| Minoxidil | Dimetacrine may decrease the antihypertensive activities of Minoxidil. |
| Treprostinil | Dimetacrine may decrease the antihypertensive activities of Treprostinil. |
| Amlodipine | Dimetacrine may decrease the antihypertensive activities of Amlodipine. |
| Nimodipine | Dimetacrine may decrease the antihypertensive activities of Nimodipine. |
| Prazosin | Dimetacrine may decrease the antihypertensive activities of Prazosin. |
| Trandolapril | Dimetacrine may decrease the antihypertensive activities of Trandolapril. |
| Lercanidipine | Dimetacrine may decrease the antihypertensive activities of Lercanidipine. |
| Benazepril | Dimetacrine may decrease the antihypertensive activities of Benazepril. |
| Bosentan | Dimetacrine may decrease the antihypertensive activities of Bosentan. |
| Enalapril | Dimetacrine may decrease the antihypertensive activities of Enalapril. |
| Doxazosin | Dimetacrine may decrease the antihypertensive activities of Doxazosin. |
| Candoxatril | Dimetacrine may decrease the antihypertensive activities of Candoxatril. |
| Losartan | Dimetacrine may decrease the antihypertensive activities of Losartan. |
| Moexipril | Dimetacrine may decrease the antihypertensive activities of Moexipril. |
| Nitroglycerin | Dimetacrine may decrease the antihypertensive activities of Nitroglycerin. |
| Cryptenamine | Dimetacrine may decrease the antihypertensive activities of Cryptenamine. |
| Candesartan cilexetil | Dimetacrine may decrease the antihypertensive activities of Candesartan cilexetil. |
| Eprosartan | Dimetacrine may decrease the antihypertensive activities of Eprosartan. |
| Quinapril | Dimetacrine may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Dimetacrine may decrease the antihypertensive activities of Telmisartan. |
| Felodipine | Dimetacrine may decrease the antihypertensive activities of Felodipine. |
| Irbesartan | Dimetacrine may decrease the antihypertensive activities of Irbesartan. |
| Nitrendipine | Dimetacrine may decrease the antihypertensive activities of Nitrendipine. |
| Deserpidine | Dimetacrine may decrease the antihypertensive activities of Deserpidine. |
| Carvedilol | Dimetacrine may decrease the antihypertensive activities of Carvedilol. |
| Bretylium | Dimetacrine may decrease the antihypertensive activities of Bretylium. |
| Terazosin | Dimetacrine may decrease the antihypertensive activities of Terazosin. |
| Acebutolol | Dimetacrine may decrease the antihypertensive activities of Acebutolol. |
| Captopril | Dimetacrine may decrease the antihypertensive activities of Captopril. |
| Bepridil | Dimetacrine may decrease the antihypertensive activities of Bepridil. |
| Bevantolol | Dimetacrine may decrease the antihypertensive activities of Bevantolol. |
| Practolol | Dimetacrine may decrease the antihypertensive activities of Practolol. |
| Cilazapril | Dimetacrine may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Dimetacrine may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Dimetacrine may decrease the antihypertensive activities of Spirapril. |
| Mibefradil | Dimetacrine may decrease the antihypertensive activities of Mibefradil. |
| Dexpropranolol | Dimetacrine may decrease the antihypertensive activities of Dexpropranolol. |
| Debrisoquine | Dimetacrine may decrease the antihypertensive activities of Debrisoquine. |
| Sitaxentan | Dimetacrine may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Dimetacrine may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Dimetacrine may decrease the antihypertensive activities of Diethylnorspermine. |
| Nilvadipine | Dimetacrine may decrease the antihypertensive activities of Nilvadipine. |
| Pinacidil | Dimetacrine may decrease the antihypertensive activities of Pinacidil. |
| Bupranolol | Dimetacrine may decrease the antihypertensive activities of Bupranolol. |
| Temocapril | Dimetacrine may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Dimetacrine may decrease the antihypertensive activities of Riociguat. |
| Indenolol | Dimetacrine may decrease the antihypertensive activities of Indenolol. |
| Aliskiren | Dimetacrine may decrease the antihypertensive activities of Aliskiren. |
| Trimazosin | Dimetacrine may decrease the antihypertensive activities of Trimazosin. |
| Lacidipine | Dimetacrine may decrease the antihypertensive activities of Lacidipine. |
| Manidipine | Dimetacrine may decrease the antihypertensive activities of Manidipine. |
| Niguldipine | Dimetacrine may decrease the antihypertensive activities of Niguldipine. |
| Rauwolfia serpentina root | Dimetacrine may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Selexipag | Dimetacrine may decrease the antihypertensive activities of Selexipag. |
| Angiotensin 1-7 | Dimetacrine may decrease the antihypertensive activities of Angiotensin 1-7. |
| Talinolol | Dimetacrine may decrease the antihypertensive activities of Talinolol. |
| Imidapril | Dimetacrine may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Dimetacrine may decrease the antihypertensive activities of BQ-123. |
| Landiolol | Dimetacrine may decrease the antihypertensive activities of Landiolol. |
| Dihydralazine | Dimetacrine may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Dimetacrine may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Dimetacrine may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Dimetacrine may decrease the antihypertensive activities of Delapril. |
| Vincamine | Dimetacrine may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Dimetacrine may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Dimetacrine may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Dimetacrine may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Dimetacrine may decrease the antihypertensive activities of Endralazine. |
| Esatenolol | Dimetacrine may decrease the antihypertensive activities of Esatenolol. |
| Cadralazine | Dimetacrine may decrease the antihypertensive activities of Cadralazine. |
| Cloranolol | Dimetacrine may decrease the antihypertensive activities of Cloranolol. |
| Bietaserpine | Dimetacrine may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Dimetacrine may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Dimetacrine may decrease the antihypertensive activities of Methoserpidine. |
| Epanolol | Dimetacrine may decrease the antihypertensive activities of Epanolol. |
| Guanoclor | Dimetacrine may decrease the antihypertensive activities of Guanoclor. |
| Candesartan | Dimetacrine may decrease the antihypertensive activities of Candesartan. |
| Dexniguldipine | Dimetacrine may decrease the antihypertensive activities of Dexniguldipine. |
| Tocopherylquinone | Dimetacrine may decrease the antihypertensive activities of Tocopherylquinone. |
| Benazeprilat | Dimetacrine may decrease the antihypertensive activities of Benazeprilat. |
| Fosinoprilat | Dimetacrine may decrease the antihypertensive activities of Fosinoprilat. |
| Ramiprilat | Dimetacrine may decrease the antihypertensive activities of Ramiprilat. |
| Perindoprilat | Dimetacrine may decrease the antihypertensive activities of Perindoprilat. |
| Quinaprilat | Dimetacrine may decrease the antihypertensive activities of Quinaprilat. |
| Metoprolol | Dimetacrine may decrease the antihypertensive activities of Metoprolol. |
| Isradipine | Dimetacrine may decrease the antihypertensive activities of Isradipine. |
| Nitroprusside | Dimetacrine may decrease the antihypertensive activities of Nitroprusside. |
| Timolol | Dimetacrine may decrease the antihypertensive activities of Timolol. |
| Nisoldipine | Dimetacrine may decrease the antihypertensive activities of Nisoldipine. |
| Fosinopril | Dimetacrine may decrease the antihypertensive activities of Fosinopril. |
| Propranolol | Dimetacrine may decrease the antihypertensive activities of Propranolol. |