Etofibrate

DB08983

small molecule experimental

Deskripsi

Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations.

Struktur Molekul 2D

Berat 363.792
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

157 Data
Clofibrate The risk or severity of adverse effects can be increased when Clofibrate is combined with Etofibrate.
Fenofibrate The risk or severity of adverse effects can be increased when Fenofibrate is combined with Etofibrate.
Gemfibrozil The risk or severity of adverse effects can be increased when Gemfibrozil is combined with Etofibrate.
Bezafibrate The risk or severity of adverse effects can be increased when Bezafibrate is combined with Etofibrate.
Ciprofibrate The risk or severity of adverse effects can be increased when Etofibrate is combined with Ciprofibrate.
Simfibrate The risk or severity of adverse effects can be increased when Etofibrate is combined with Simfibrate.
Ronifibrate The risk or severity of adverse effects can be increased when Etofibrate is combined with Ronifibrate.
Aluminium clofibrate The risk or severity of adverse effects can be increased when Etofibrate is combined with Aluminium clofibrate.
Clofibride The risk or severity of adverse effects can be increased when Etofibrate is combined with Clofibride.
Fenofibric acid The risk or severity of adverse effects can be increased when Etofibrate is combined with Fenofibric acid.
Ezetimibe The serum concentration of Ezetimibe can be increased when it is combined with Etofibrate.
Glycochenodeoxycholic Acid The therapeutic efficacy of Glycochenodeoxycholic Acid can be decreased when used in combination with Etofibrate.
Cholic Acid The therapeutic efficacy of Cholic Acid can be decreased when used in combination with Etofibrate.
Glycocholic acid The therapeutic efficacy of Glycocholic acid can be decreased when used in combination with Etofibrate.
Deoxycholic acid The therapeutic efficacy of Deoxycholic acid can be decreased when used in combination with Etofibrate.
Taurocholic acid The therapeutic efficacy of Taurocholic acid can be decreased when used in combination with Etofibrate.
Obeticholic acid The therapeutic efficacy of Obeticholic acid can be decreased when used in combination with Etofibrate.
Chenodeoxycholic acid The therapeutic efficacy of Chenodeoxycholic acid can be decreased when used in combination with Etofibrate.
Taurochenodeoxycholic acid The therapeutic efficacy of Taurochenodeoxycholic acid can be decreased when used in combination with Etofibrate.
Tauroursodeoxycholic acid The therapeutic efficacy of Tauroursodeoxycholic acid can be decreased when used in combination with Etofibrate.
Bamet-UD2 The therapeutic efficacy of Bamet-UD2 can be decreased when used in combination with Etofibrate.
Dehydrocholic acid The therapeutic efficacy of Dehydrocholic acid can be decreased when used in combination with Etofibrate.
Hyodeoxycholic Acid The therapeutic efficacy of Hyodeoxycholic Acid can be decreased when used in combination with Etofibrate.
Ursodeoxycholic acid The therapeutic efficacy of Ursodeoxycholic acid can be decreased when used in combination with Etofibrate.
Cyclosporine The risk or severity of renal failure can be increased when Cyclosporine is combined with Etofibrate.
Glimepiride The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Glimepiride.
Acetohexamide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Acetohexamide.
Chlorpropamide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Chlorpropamide.
Tolazamide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Tolazamide.
Glyburide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Glyburide.
Glipizide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Glipizide.
Gliclazide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Gliclazide.
Tolbutamide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Tolbutamide.
Gliquidone The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Gliquidone.
Glisoxepide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Glisoxepide.
Glibornuride The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Glibornuride.
Carbutamide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Carbutamide.
Metahexamide The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Metahexamide.
Colestipol Colestipol can cause a decrease in the absorption of Etofibrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Etofibrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Colesevelam Colesevelam can cause a decrease in the absorption of Etofibrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cholestyramine Cholestyramine can cause a decrease in the absorption of Etofibrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Dicoumarol The risk or severity of bleeding can be increased when Etofibrate is combined with Dicoumarol.
Phenindione The risk or severity of bleeding can be increased when Etofibrate is combined with Phenindione.
Warfarin The risk or severity of bleeding can be increased when Etofibrate is combined with Warfarin.
Phenprocoumon The risk or severity of bleeding can be increased when Etofibrate is combined with Phenprocoumon.
Acenocoumarol The risk or severity of bleeding can be increased when Etofibrate is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of bleeding can be increased when Etofibrate is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of bleeding can be increased when Etofibrate is combined with Coumarin.
(R)-warfarin The risk or severity of bleeding can be increased when Etofibrate is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of bleeding can be increased when Etofibrate is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of bleeding can be increased when Etofibrate is combined with Fluindione.
Clorindione The risk or severity of bleeding can be increased when Etofibrate is combined with Clorindione.
Diphenadione The risk or severity of bleeding can be increased when Etofibrate is combined with Diphenadione.
Tioclomarol The risk or severity of bleeding can be increased when Etofibrate is combined with Tioclomarol.
(S)-Warfarin The risk or severity of bleeding can be increased when Etofibrate is combined with (S)-Warfarin.
Tacrolimus Tacrolimus may increase the nephrotoxic activities of Etofibrate.
Pravastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Etofibrate is combined with Pravastatin.
Lovastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Etofibrate is combined with Lovastatin.
Cerivastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Etofibrate is combined with Cerivastatin.
Simvastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Etofibrate is combined with Simvastatin.
Atorvastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Etofibrate is combined with Atorvastatin.
Fluvastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Etofibrate is combined with Fluvastatin.
Rosuvastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Etofibrate is combined with Rosuvastatin.
Mevastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Etofibrate is combined with Mevastatin.
Pitavastatin The risk or severity of myopathy and rhabdomyolysis can be increased when Etofibrate is combined with Pitavastatin.
Leuprolide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Etofibrate.
Somatotropin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Somatotropin is combined with Etofibrate.
Infliximab The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Infliximab is combined with Etofibrate.
Daptomycin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Etofibrate.
Baclofen The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Etofibrate.
Sildenafil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Sildenafil is combined with Etofibrate.
Indinavir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Etofibrate.
Cladribine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cladribine is combined with Etofibrate.
Phenytoin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Phenytoin is combined with Etofibrate.
Pamidronic acid The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pamidronic acid is combined with Etofibrate.
Mefloquine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Mefloquine is combined with Etofibrate.
Tacrine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Tacrine is combined with Etofibrate.
Carbimazole The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Carbimazole is combined with Etofibrate.
Trimethoprim The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Trimethoprim is combined with Etofibrate.
Betamethasone The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Betamethasone is combined with Etofibrate.
Montelukast The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Montelukast is combined with Etofibrate.
Zidovudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Zidovudine is combined with Etofibrate.
Cimetidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cimetidine is combined with Etofibrate.
Ritonavir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ritonavir is combined with Etofibrate.
Lercanidipine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Lercanidipine is combined with Etofibrate.
Ciprofloxacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ciprofloxacin is combined with Etofibrate.
Vincristine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Vincristine is combined with Etofibrate.
Propylthiouracil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Propylthiouracil is combined with Etofibrate.
Methotrexate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Methotrexate is combined with Etofibrate.
Enalapril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Enalapril is combined with Etofibrate.
Nizatidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nizatidine is combined with Etofibrate.
Ivermectin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ivermectin is combined with Etofibrate.
Chloroquine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Chloroquine is combined with Etofibrate.
Triamcinolone The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Triamcinolone is combined with Etofibrate.
Niacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Niacin is combined with Etofibrate.
Alendronic acid The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Alendronic acid is combined with Etofibrate.
Stavudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Stavudine is combined with Etofibrate.
Nafarelin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nafarelin is combined with Etofibrate.
Amphotericin B The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Amphotericin B is combined with Etofibrate.

Referensi & Sumber

Synthesis reference: U.S. Patent 4,028,369.

Contoh Produk & Brand

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