Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Ceritinib | Fendiline may increase the bradycardic activities of Ceritinib. |
| Ivabradine | Fendiline may increase the bradycardic activities of Ivabradine. |
| Ruxolitinib | Ruxolitinib may increase the bradycardic activities of Fendiline. |
| Cimetidine | The serum concentration of Fendiline can be increased when it is combined with Cimetidine. |
| Clopidogrel | The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Fendiline. |
| Efavirenz | The serum concentration of Fendiline can be decreased when it is combined with Efavirenz. |
| Melatonin | The therapeutic efficacy of Fendiline can be decreased when used in combination with Melatonin. |
| Nafcillin | The therapeutic efficacy of Fendiline can be decreased when used in combination with Nafcillin. |
| Nitroprusside | Fendiline may increase the hypotensive activities of Nitroprusside. |
| Dantrolene | The risk or severity of hyperkalemia can be increased when Dantrolene is combined with Fendiline. |
| Lithium citrate | The risk or severity of adverse effects can be increased when Fendiline is combined with Lithium citrate. |
| Lithium carbonate | The risk or severity of adverse effects can be increased when Fendiline is combined with Lithium carbonate. |
| Lithium hydroxide | The risk or severity of adverse effects can be increased when Fendiline is combined with Lithium hydroxide. |
| Boceprevir | The serum concentration of Fendiline can be increased when it is combined with Boceprevir. |
| Tocainide | Tocainide may increase the arrhythmogenic activities of Fendiline. |
| Aprindine | Aprindine may increase the arrhythmogenic activities of Fendiline. |
| Xylometazoline | Xylometazoline may increase the arrhythmogenic activities of Fendiline. |
| Sparteine | Sparteine may increase the arrhythmogenic activities of Fendiline. |
| Fasudil | Fasudil may increase the arrhythmogenic activities of Fendiline. |
| Carteolol | Fendiline may increase the arrhythmogenic activities of Carteolol. |
| Metipranolol | Fendiline may increase the arrhythmogenic activities of Metipranolol. |
| Tropisetron | Fendiline may increase the arrhythmogenic activities of Tropisetron. |
| Spiradoline | Fendiline may increase the arrhythmogenic activities of Spiradoline. |
| Tiracizine | Fendiline may increase the arrhythmogenic activities of Tiracizine. |
| Ethacizine | Fendiline may increase the arrhythmogenic activities of Ethacizine. |
| Hydroquinine | Fendiline may increase the arrhythmogenic activities of Hydroquinine. |
| Bioallethrin | Fendiline may increase the arrhythmogenic activities of Bioallethrin. |
| Fosfructose | Fendiline may increase the arrhythmogenic activities of Fosfructose. |
| Hydroquinidine | Fendiline may increase the arrhythmogenic activities of Hydroquinidine. |
| SOR-C13 | Fendiline may increase the arrhythmogenic activities of SOR-C13. |
| Digoxin | Digoxin may increase the arrhythmogenic activities of Fendiline. |
| Acetyldigitoxin | Acetyldigitoxin may increase the arrhythmogenic activities of Fendiline. |
| Deslanoside | Deslanoside may increase the arrhythmogenic activities of Fendiline. |
| Cymarin | Fendiline may increase the arrhythmogenic activities of Cymarin. |
| Metildigoxin | Fendiline may increase the arrhythmogenic activities of Metildigoxin. |
| Acetyldigoxin | Fendiline may increase the arrhythmogenic activities of Acetyldigoxin. |
| Disopyramide | Disopyramide may increase the arrhythmogenic activities of Fendiline. |
| Ibutilide | Ibutilide may increase the arrhythmogenic activities of Fendiline. |
| Procainamide | Procainamide may increase the arrhythmogenic activities of Fendiline. |
| Bepridil | Bepridil may increase the arrhythmogenic activities of Fendiline. |
| Terodiline | Fendiline may increase the arrhythmogenic activities of Terodiline. |
| Diltiazem | Diltiazem may increase the arrhythmogenic activities of Fendiline. |
| Nimodipine | Nimodipine may increase the arrhythmogenic activities of Fendiline. |
| Cinnarizine | Cinnarizine may increase the arrhythmogenic activities of Fendiline. |
| Atropine | Atropine may increase the arrhythmogenic activities of Fendiline. |
| Adenosine | Adenosine may increase the arrhythmogenic activities of Fendiline. |
| Levosimendan | Levosimendan may increase the arrhythmogenic activities of Fendiline. |
| Nifedipine | Nifedipine may increase the arrhythmogenic activities of Fendiline. |
| Flecainide | Flecainide may increase the arrhythmogenic activities of Fendiline. |
| Prenylamine | Prenylamine may increase the arrhythmogenic activities of Fendiline. |
| Fluspirilene | Fluspirilene may increase the arrhythmogenic activities of Fendiline. |
| Azimilide | Azimilide may increase the arrhythmogenic activities of Fendiline. |
| Tedisamil | Tedisamil may increase the arrhythmogenic activities of Fendiline. |
| Nilvadipine | Nilvadipine may increase the arrhythmogenic activities of Fendiline. |
| Eperisone | Fendiline may increase the arrhythmogenic activities of Eperisone. |
| Melperone | Fendiline may increase the arrhythmogenic activities of Melperone. |
| Benidipine | Fendiline may increase the arrhythmogenic activities of Benidipine. |
| Simendan | Fendiline may increase the arrhythmogenic activities of Simendan. |
| Otilonium | Fendiline may increase the arrhythmogenic activities of Otilonium. |
| Nizofenone | Fendiline may increase the arrhythmogenic activities of Nizofenone. |
| Bunaftine | Fendiline may increase the arrhythmogenic activities of Bunaftine. |
| Lorcainide | Fendiline may increase the arrhythmogenic activities of Lorcainide. |
| Penfluridol | Fendiline may increase the arrhythmogenic activities of Penfluridol. |
| Dexverapamil | Fendiline may increase the arrhythmogenic activities of Dexverapamil. |
| Isradipine | Isradipine may increase the arrhythmogenic activities of Fendiline. |
| Trimethadione | Trimethadione may increase the arrhythmogenic activities of Fendiline. |
| Amlodipine | Amlodipine may increase the arrhythmogenic activities of Fendiline. |
| Hyoscyamine | Hyoscyamine may increase the arrhythmogenic activities of Fendiline. |
| Lamotrigine | Lamotrigine may increase the arrhythmogenic activities of Fendiline. |
| Nicardipine | Nicardipine may increase the arrhythmogenic activities of Fendiline. |
| Verapamil | Verapamil may increase the arrhythmogenic activities of Fendiline. |
| Losartan | Losartan may increase the arrhythmogenic activities of Fendiline. |
| Moricizine | Moricizine may increase the arrhythmogenic activities of Fendiline. |
| Levomenthol | Levomenthol may increase the arrhythmogenic activities of Fendiline. |
| Zonisamide | Zonisamide may increase the arrhythmogenic activities of Fendiline. |
| Nitrendipine | Nitrendipine may increase the arrhythmogenic activities of Fendiline. |
| Perhexiline | Perhexiline may increase the arrhythmogenic activities of Fendiline. |
| Bretylium | Bretylium may increase the arrhythmogenic activities of Fendiline. |
| Encainide | Encainide may increase the arrhythmogenic activities of Fendiline. |
| Ajmaline | Ajmaline may increase the arrhythmogenic activities of Fendiline. |
| Methsuximide | Methsuximide may increase the arrhythmogenic activities of Fendiline. |
| Vernakalant | Vernakalant may increase the arrhythmogenic activities of Fendiline. |
| Ziconotide | Ziconotide may increase the arrhythmogenic activities of Fendiline. |
| Cariporide | Cariporide may increase the arrhythmogenic activities of Fendiline. |
| Trimebutine | Fendiline may increase the arrhythmogenic activities of Trimebutine. |
| Pinaverium | Fendiline may increase the arrhythmogenic activities of Pinaverium. |
| Aranidipine | Fendiline may increase the arrhythmogenic activities of Aranidipine. |
| Efonidipine | Fendiline may increase the arrhythmogenic activities of Efonidipine. |
| Lacidipine | Fendiline may increase the arrhythmogenic activities of Lacidipine. |
| Niguldipine | Fendiline may increase the arrhythmogenic activities of Niguldipine. |
| Tetrahydropalmatine | Fendiline may increase the arrhythmogenic activities of Tetrahydropalmatine. |
| Pilsicainide | Fendiline may increase the arrhythmogenic activities of Pilsicainide. |
| Cicletanine | Fendiline may increase the arrhythmogenic activities of Cicletanine. |
| Gallopamil | Fendiline may increase the arrhythmogenic activities of Gallopamil. |
| Cibenzoline | Fendiline may increase the arrhythmogenic activities of Cibenzoline. |
| Bencyclane | Fendiline may increase the arrhythmogenic activities of Bencyclane. |
| Prajmaline | Fendiline may increase the arrhythmogenic activities of Prajmaline. |
| Lorajmine | Fendiline may increase the arrhythmogenic activities of Lorajmine. |
| Lidoflazine | Fendiline may increase the arrhythmogenic activities of Lidoflazine. |
| Lercanidipine | Lercanidipine may increase the arrhythmogenic activities of Fendiline. |