Dimetotiazine

Peta Jejaring Molekuler

Obat Target Gen Interaksi Enzim Transporter Carrier

Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

1. Pendahuluan & Konsep

Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).

2. Sumber Data (Validasi)

Data Obat: Diekstraksi dari elemen drugbank-id dan name pada skema XML DrugBank.
Target Protein: Diambil dari elemen targets/target yang memuat polipeptida sasaran.
Genetik: Disinkronisasi dari sub-elemen gene-name dan varian snp-effects.
Genetik: Jumlah titik node dibatasi pada maksimal 10 (Slice=10) interaksi untuk menghindari tumpukan data.

3. Algoritma Visualisasi

Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.

4. Legenda Visual

Obat Utama (Pusat Analisis)

Target Protein (Mekanisme)

Gen (Faktor Genetik)

Metode ini mendukung analisis Precision Medicine dan evaluasi risiko Drug-Drug Interaction (DDI).

Profil Farmakokinetik

Waktu Paruh (Half-Life) -

Volume Distribusi -

Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

30 Data

Benzylpenicilloyl polylysine	Dimetotiazine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Betahistine	The therapeutic efficacy of Betahistine can be decreased when used in combination with Dimetotiazine.
Hyaluronidase (ovine)	The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Dimetotiazine.
Hyaluronidase (human recombinant)	The therapeutic efficacy of Hyaluronidase (human recombinant) can be decreased when used in combination with Dimetotiazine.
Hyaluronidase	The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Dimetotiazine.
Amphetamine	Amphetamine may decrease the sedative activities of Dimetotiazine.
Phentermine	Phentermine may decrease the sedative activities of Dimetotiazine.
Pseudoephedrine	Pseudoephedrine may decrease the sedative activities of Dimetotiazine.
Benzphetamine	Benzphetamine may decrease the sedative activities of Dimetotiazine.
Diethylpropion	Diethylpropion may decrease the sedative activities of Dimetotiazine.
Lisdexamfetamine	Lisdexamfetamine may decrease the sedative activities of Dimetotiazine.
Mephentermine	Mephentermine may decrease the sedative activities of Dimetotiazine.
MMDA	MMDA may decrease the sedative activities of Dimetotiazine.
Midomafetamine	Midomafetamine may decrease the sedative activities of Dimetotiazine.
2,5-Dimethoxy-4-ethylamphetamine	2,5-Dimethoxy-4-ethylamphetamine may decrease the sedative activities of Dimetotiazine.
4-Bromo-2,5-dimethoxyamphetamine	4-Bromo-2,5-dimethoxyamphetamine may decrease the sedative activities of Dimetotiazine.
Tenamfetamine	Tenamfetamine may decrease the sedative activities of Dimetotiazine.
Chlorphentermine	Chlorphentermine may decrease the sedative activities of Dimetotiazine.
Methylenedioxyethamphetamine	Methylenedioxyethamphetamine may decrease the sedative activities of Dimetotiazine.
Dextroamphetamine	Dextroamphetamine may decrease the sedative activities of Dimetotiazine.
Metamfetamine	Metamfetamine may decrease the sedative activities of Dimetotiazine.
Iofetamine I-123	Iofetamine I-123 may decrease the sedative activities of Dimetotiazine.
Ritobegron	Ritobegron may decrease the sedative activities of Dimetotiazine.
Mephedrone	Mephedrone may decrease the sedative activities of Dimetotiazine.
Methoxyphenamine	Methoxyphenamine may decrease the sedative activities of Dimetotiazine.
Gepefrine	Gepefrine may decrease the sedative activities of Dimetotiazine.
2,5-Dimethoxy-4-ethylthioamphetamine	2,5-Dimethoxy-4-ethylthioamphetamine may decrease the sedative activities of Dimetotiazine.
Phendimetrazine	Phendimetrazine may decrease the sedative activities of Dimetotiazine.
Pitolisant	The therapeutic efficacy of Pitolisant can be decreased when used in combination with Dimetotiazine.
Hyoscyamine	Dimetotiazine may increase the anticholinergic activities of Hyoscyamine.

Referensi & Sumber

Synthesis reference: British Patent 814,512.

Contoh Produk & Brand

Produk: 0 • International brands: 0

Belum ada data produk/brand untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field produk/brand.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.

Deskripsi

Struktur Molekul 2D

Deskripsi metode visualisasi