Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported hematological effects caused by Indalpine, it was abruptly withdrawn from the US market.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Cyproheptadine | The therapeutic efficacy of Indalpine can be decreased when used in combination with Cyproheptadine. |
| Desmopressin | The risk or severity of hyponatremia can be increased when Indalpine is combined with Desmopressin. |
| Ioflupane I-123 | Indalpine may decrease effectiveness of Ioflupane I-123 as a diagnostic agent. |
| Linezolid | The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Indalpine. |
| Metyrosine | The risk or severity of extrapyramidal symptoms can be increased when Metyrosine is combined with Indalpine. |
| Pimozide | The risk or severity of QTc prolongation can be increased when Indalpine is combined with Pimozide. |
| Buprenorphine | Indalpine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Indalpine. |
| Dronabinol | The serum concentration of Dronabinol can be increased when it is combined with Indalpine. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Indalpine. |
| Hydrocodone | Indalpine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Indalpine. |
| Magnesium sulfate | The therapeutic efficacy of Indalpine can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Indalpine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Indalpine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Indalpine. |
| Orphenadrine | Indalpine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Indalpine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Indalpine. |
| Pramipexole | Indalpine may increase the sedative activities of Pramipexole. |
| Ropinirole | Indalpine may increase the sedative activities of Ropinirole. |
| Rotigotine | Indalpine may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Indalpine. |
| Sodium oxybate | Indalpine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Indalpine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Indalpine. |
| Thalidomide | Indalpine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Indalpine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Brexpiprazole | The metabolism of Brexpiprazole can be decreased when combined with Indalpine. |
| Eliglustat | The metabolism of Eliglustat can be decreased when combined with Indalpine. |
| Everolimus | The metabolism of Everolimus can be decreased when combined with Indalpine. |
| Flibanserin | The metabolism of Flibanserin can be decreased when combined with Indalpine. |
| Ibrutinib | The metabolism of Ibrutinib can be decreased when combined with Indalpine. |
| Ivabradine | The metabolism of Ivabradine can be decreased when combined with Indalpine. |
| Ivacaftor | The metabolism of Ivacaftor can be decreased when combined with Indalpine. |
| Lurasidone | The metabolism of Lurasidone can be decreased when combined with Indalpine. |
| Naloxegol | The metabolism of Naloxegol can be decreased when combined with Indalpine. |
| Olaparib | The metabolism of Olaparib can be decreased when combined with Indalpine. |
| Ranolazine | The metabolism of Ranolazine can be decreased when combined with Indalpine. |
| Sonidegib | The metabolism of Sonidegib can be decreased when combined with Indalpine. |
| Avanafil | The metabolism of Avanafil can be decreased when combined with Indalpine. |
| Eplerenone | The metabolism of Eplerenone can be decreased when combined with Indalpine. |
| Cilostazol | The metabolism of Cilostazol can be decreased when combined with Indalpine. |
| Colchicine | The metabolism of Colchicine can be decreased when combined with Indalpine. |
| Fentanyl | The risk or severity of serotonin syndrome can be increased when Fentanyl is combined with Indalpine. |
| Iloperidone | The metabolism of Iloperidone can be decreased when combined with Indalpine. |
| Retapamulin | The metabolism of Retapamulin can be decreased when combined with Indalpine. |
| Tofacitinib | The metabolism of Tofacitinib can be decreased when combined with Indalpine. |
| Vardenafil | The metabolism of Vardenafil can be decreased when combined with Indalpine. |
| Zopiclone | The metabolism of Zopiclone can be decreased when combined with Indalpine. |
| Lovastatin | The metabolism of Lovastatin can be decreased when combined with Indalpine. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Indalpine. |
| Alfuzosin | The metabolism of Alfuzosin can be decreased when combined with Indalpine. |
| Alprazolam | The metabolism of Alprazolam can be decreased when combined with Indalpine. |
| Warfarin | The serum concentration of Warfarin can be increased when it is combined with Indalpine. |
| Acenocoumarol | The serum concentration of Acenocoumarol can be increased when it is combined with Indalpine. |
| (R)-warfarin | The serum concentration of (R)-warfarin can be increased when it is combined with Indalpine. |
| R,S-Warfarin alcohol | The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with Indalpine. |
| S,R-Warfarin alcohol | The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with Indalpine. |
| (S)-Warfarin | The serum concentration of (S)-Warfarin can be increased when it is combined with Indalpine. |
| Midazolam | The serum concentration of Midazolam can be increased when it is combined with Indalpine. |
| Tacrolimus | The serum concentration of Tacrolimus can be increased when it is combined with Indalpine. |
| Atorvastatin | The metabolism of Atorvastatin can be decreased when combined with Indalpine. |
| Tedizolid phosphate | The risk or severity of serotonin syndrome can be increased when Tedizolid phosphate is combined with Indalpine. |
| Mirtazapine | Indalpine may increase the serotonergic activities of Mirtazapine. |
| Morphine | The risk or severity of serotonin syndrome can be increased when Morphine is combined with Indalpine. |
| Codeine | The risk or severity of serotonin syndrome can be increased when Codeine is combined with Indalpine. |
| Hydromorphone | The risk or severity of serotonin syndrome can be increased when Hydromorphone is combined with Indalpine. |
| Oxycodone | The risk or severity of serotonin syndrome can be increased when Oxycodone is combined with Indalpine. |
| Butorphanol | The risk or severity of serotonin syndrome can be increased when Butorphanol is combined with Indalpine. |
| Dextropropoxyphene | The risk or severity of serotonin syndrome can be increased when Dextropropoxyphene is combined with Indalpine. |
| Pentazocine | The risk or severity of serotonin syndrome can be increased when Pentazocine is combined with Indalpine. |
| Sufentanil | The risk or severity of serotonin syndrome can be increased when Sufentanil is combined with Indalpine. |
| Nalbuphine | The risk or severity of serotonin syndrome can be increased when Nalbuphine is combined with Indalpine. |
| Levorphanol | The risk or severity of serotonin syndrome can be increased when Levorphanol is combined with Indalpine. |
| Remifentanil | The risk or severity of serotonin syndrome can be increased when Remifentanil is combined with Indalpine. |
| Diphenoxylate | The risk or severity of serotonin syndrome can be increased when Diphenoxylate is combined with Indalpine. |
| Oxymorphone | The risk or severity of serotonin syndrome can be increased when Oxymorphone is combined with Indalpine. |
| Dezocine | The risk or severity of serotonin syndrome can be increased when Dezocine is combined with Indalpine. |
| Methadyl acetate | The risk or severity of serotonin syndrome can be increased when Methadyl acetate is combined with Indalpine. |
| Dihydroetorphine | The risk or severity of serotonin syndrome can be increased when Dihydroetorphine is combined with Indalpine. |
| Diamorphine | The risk or severity of serotonin syndrome can be increased when Diamorphine is combined with Indalpine. |
| Ethylmorphine | The risk or severity of serotonin syndrome can be increased when Ethylmorphine is combined with Indalpine. |
| Etorphine | The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Indalpine. |
| Dextromoramide | The risk or severity of serotonin syndrome can be increased when Dextromoramide is combined with Indalpine. |
| Desomorphine | The risk or severity of serotonin syndrome can be increased when Desomorphine is combined with Indalpine. |
| Carfentanil | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Indalpine. |
| Dihydrocodeine | The risk or severity of serotonin syndrome can be increased when Dihydrocodeine is combined with Indalpine. |
| Alphacetylmethadol | The risk or severity of serotonin syndrome can be increased when Alphacetylmethadol is combined with Indalpine. |
| Dihydromorphine | The risk or severity of serotonin syndrome can be increased when Dihydromorphine is combined with Indalpine. |
| Ketobemidone | The risk or severity of serotonin syndrome can be increased when Ketobemidone is combined with Indalpine. |
| DPDPE | The risk or severity of serotonin syndrome can be increased when DPDPE is combined with Indalpine. |
| Lofentanil | The risk or severity of serotonin syndrome can be increased when Lofentanil is combined with Indalpine. |
| Opium | The risk or severity of serotonin syndrome can be increased when Opium is combined with Indalpine. |
| Normethadone | The risk or severity of serotonin syndrome can be increased when Normethadone is combined with Indalpine. |
| Piritramide | The risk or severity of serotonin syndrome can be increased when Piritramide is combined with Indalpine. |
| Alphaprodine | The risk or severity of serotonin syndrome can be increased when Alphaprodine is combined with Indalpine. |
| Meptazinol | The risk or severity of serotonin syndrome can be increased when Meptazinol is combined with Indalpine. |
| Phenoperidine | The risk or severity of serotonin syndrome can be increased when Phenoperidine is combined with Indalpine. |
| Phenazocine | The risk or severity of serotonin syndrome can be increased when Phenazocine is combined with Indalpine. |