Bopindolol

DB08807

small molecule experimental

Deskripsi

Bopindolol (INN) is an ester prodrug for the beta blocker pindolol.

Struktur Molekul 2D

Berat 380.48
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1077 Data
Ceritinib Bopindolol may increase the bradycardic activities of Ceritinib.
Ivabradine Bopindolol may increase the bradycardic activities of Ivabradine.
Ruxolitinib Ruxolitinib may increase the bradycardic activities of Bopindolol.
Amiodarone The therapeutic efficacy of Bopindolol can be increased when used in combination with Amiodarone.
Bupivacaine The serum concentration of Bupivacaine can be increased when it is combined with Bopindolol.
Dipyridamole Dipyridamole may increase the bradycardic activities of Bopindolol.
Disopyramide Disopyramide may increase the bradycardic activities of Bopindolol.
Dronedarone Dronedarone may increase the bradycardic activities of Bopindolol.
Fingolimod Bopindolol may increase the bradycardic activities of Fingolimod.
Floctafenine The risk or severity of adverse effects can be increased when Bopindolol is combined with Floctafenine.
Mepivacaine The serum concentration of Mepivacaine can be increased when it is combined with Bopindolol.
Methacholine Bopindolol may increase the bronchoconstrictory activities of Methacholine.
Midodrine The therapeutic efficacy of Midodrine can be decreased when used in combination with Bopindolol.
Nifedipine The risk or severity of congestive heart failure and hypotension can be increased when Nifedipine is combined with Bopindolol.
Propafenone The risk or severity of adverse effects can be increased when Propafenone is combined with Bopindolol.
Regorafenib Regorafenib may increase the bradycardic activities of Bopindolol.
Reserpine Reserpine may increase the hypotensive activities of Bopindolol.
Deserpidine Deserpidine may increase the hypotensive activities of Bopindolol.
Guanethidine Guanethidine may increase the hypotensive activities of Bopindolol.
Rivastigmine Bopindolol may increase the bradycardic activities of Rivastigmine.
Mirabegron The serum concentration of Bopindolol can be increased when it is combined with Mirabegron.
Insulin argine Bopindolol may increase the hypoglycemic activities of Insulin argine.
Nicotine The risk or severity of adverse effects can be increased when Bopindolol is combined with Nicotine.
Cevimeline The risk or severity of adverse effects can be increased when Bopindolol is combined with Cevimeline.
Carbamoylcholine The risk or severity of adverse effects can be increased when Bopindolol is combined with Carbamoylcholine.
Bethanechol The risk or severity of adverse effects can be increased when Bopindolol is combined with Bethanechol.
Pilocarpine The risk or severity of adverse effects can be increased when Bopindolol is combined with Pilocarpine.
Varenicline The risk or severity of adverse effects can be increased when Bopindolol is combined with Varenicline.
Acetylcholine The risk or severity of adverse effects can be increased when Bopindolol is combined with Acetylcholine.
Arecoline The risk or severity of adverse effects can be increased when Bopindolol is combined with Arecoline.
Lobeline The risk or severity of adverse effects can be increased when Bopindolol is combined with Lobeline.
NGX267 The risk or severity of adverse effects can be increased when Bopindolol is combined with NGX267.
GTS-21 The risk or severity of adverse effects can be increased when Bopindolol is combined with GTS-21.
Epibatidine The risk or severity of adverse effects can be increased when Bopindolol is combined with Epibatidine.
Xanomeline The risk or severity of adverse effects can be increased when Bopindolol is combined with Xanomeline.
Thiethylperazine The serum concentration of Bopindolol can be increased when it is combined with Thiethylperazine.
Promazine The serum concentration of Bopindolol can be increased when it is combined with Promazine.
Prochlorperazine The serum concentration of Bopindolol can be increased when it is combined with Prochlorperazine.
Triflupromazine The serum concentration of Bopindolol can be increased when it is combined with Triflupromazine.
Fluphenazine The serum concentration of Bopindolol can be increased when it is combined with Fluphenazine.
Moricizine The serum concentration of Bopindolol can be increased when it is combined with Moricizine.
Trifluoperazine The serum concentration of Bopindolol can be increased when it is combined with Trifluoperazine.
Perphenazine The serum concentration of Bopindolol can be increased when it is combined with Perphenazine.
Mesoridazine The serum concentration of Bopindolol can be increased when it is combined with Mesoridazine.
Acetophenazine The serum concentration of Bopindolol can be increased when it is combined with Acetophenazine.
Promethazine The serum concentration of Bopindolol can be increased when it is combined with Promethazine.
Alimemazine The serum concentration of Bopindolol can be increased when it is combined with Alimemazine.
Periciazine The serum concentration of Bopindolol can be increased when it is combined with Periciazine.
Acepromazine The serum concentration of Bopindolol can be increased when it is combined with Acepromazine.
Aceprometazine The serum concentration of Bopindolol can be increased when it is combined with Aceprometazine.
Pipotiazine The serum concentration of Bopindolol can be increased when it is combined with Pipotiazine.
Thioproperazine The serum concentration of Bopindolol can be increased when it is combined with Thioproperazine.
BL-1020 The serum concentration of Bopindolol can be increased when it is combined with BL-1020.
Cyamemazine The serum concentration of Bopindolol can be increased when it is combined with Cyamemazine.
Methylene blue The serum concentration of Bopindolol can be increased when it is combined with Methylene blue.
Propiopromazine The serum concentration of Bopindolol can be increased when it is combined with Propiopromazine.
Perazine The serum concentration of Bopindolol can be increased when it is combined with Perazine.
Butaperazine The serum concentration of Bopindolol can be increased when it is combined with Butaperazine.
Chlorproethazine The serum concentration of Bopindolol can be increased when it is combined with Chlorproethazine.
Thiazinam The serum concentration of Bopindolol can be increased when it is combined with Thiazinam.
Dixyrazine The serum concentration of Bopindolol can be increased when it is combined with Dixyrazine.
Perphenazine enanthate The serum concentration of Bopindolol can be increased when it is combined with Perphenazine enanthate.
Digoxin Bopindolol may increase the bradycardic activities of Digoxin.
Acetyldigitoxin Bopindolol may increase the bradycardic activities of Acetyldigitoxin.
Deslanoside Bopindolol may increase the bradycardic activities of Deslanoside.
Ouabain Bopindolol may increase the bradycardic activities of Ouabain.
Digitoxin Bopindolol may increase the bradycardic activities of Digitoxin.
Oleandrin Bopindolol may increase the bradycardic activities of Oleandrin.
Cymarin Bopindolol may increase the bradycardic activities of Cymarin.
Proscillaridin Bopindolol may increase the bradycardic activities of Proscillaridin.
Metildigoxin Bopindolol may increase the bradycardic activities of Metildigoxin.
Lanatoside C Bopindolol may increase the bradycardic activities of Lanatoside C.
Gitoformate Bopindolol may increase the bradycardic activities of Gitoformate.
Acetyldigoxin Bopindolol may increase the bradycardic activities of Acetyldigoxin.
Peruvoside Bopindolol may increase the bradycardic activities of Peruvoside.
Lidocaine The serum concentration of Lidocaine can be increased when it is combined with Bopindolol.
Icosapent Icosapent may decrease the antihypertensive activities of Bopindolol.
Mesalazine The risk or severity of hyperkalemia can be increased when Mesalazine is combined with Bopindolol.
Indomethacin Indomethacin may decrease the antihypertensive activities of Bopindolol.
Nabumetone Nabumetone may decrease the antihypertensive activities of Bopindolol.
Ketorolac Ketorolac may decrease the antihypertensive activities of Bopindolol.
Tenoxicam Tenoxicam may decrease the antihypertensive activities of Bopindolol.
Celecoxib Celecoxib may decrease the antihypertensive activities of Bopindolol.
Tolmetin Tolmetin may decrease the antihypertensive activities of Bopindolol.
Rofecoxib Rofecoxib may decrease the antihypertensive activities of Bopindolol.
Piroxicam Piroxicam may decrease the antihypertensive activities of Bopindolol.
Fenoprofen Fenoprofen may decrease the antihypertensive activities of Bopindolol.
Valdecoxib Valdecoxib may decrease the antihypertensive activities of Bopindolol.
Diclofenac Diclofenac may decrease the antihypertensive activities of Bopindolol.
Sulindac Sulindac may decrease the antihypertensive activities of Bopindolol.
Flurbiprofen Flurbiprofen may decrease the antihypertensive activities of Bopindolol.
Etodolac Etodolac may decrease the antihypertensive activities of Bopindolol.
Mefenamic acid Mefenamic acid may decrease the antihypertensive activities of Bopindolol.
Naproxen Naproxen may decrease the antihypertensive activities of Bopindolol.
Sulfasalazine Sulfasalazine may decrease the antihypertensive activities of Bopindolol.
Phenylbutazone Phenylbutazone may decrease the antihypertensive activities of Bopindolol.
Meloxicam Meloxicam may decrease the antihypertensive activities of Bopindolol.
Carprofen Carprofen may decrease the antihypertensive activities of Bopindolol.
Diflunisal Diflunisal may decrease the antihypertensive activities of Bopindolol.
Salicylic acid Salicylic acid may decrease the antihypertensive activities of Bopindolol.

Target Protein

Beta-1 adrenergic receptor ADRB1
Beta-2 adrenergic receptor ADRB2
Beta-3 adrenergic receptor ADRB3
5-hydroxytryptamine receptor 1A HTR1A
5-hydroxytryptamine receptor 1B HTR1B

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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