Puromycin

DB08437

small molecule experimental

Deskripsi

Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate doses.

Struktur Molekul 2D

Berat 471.5096
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

873 Data
Succinylcholine The therapeutic efficacy of Succinylcholine can be increased when used in combination with Puromycin.
Metocurine iodide The therapeutic efficacy of Metocurine iodide can be increased when used in combination with Puromycin.
Gallamine triethiodide The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Puromycin.
Cisatracurium Puromycin may increase the neuromuscular blocking activities of Cisatracurium.
Rocuronium The therapeutic efficacy of Rocuronium can be increased when used in combination with Puromycin.
Atracurium besylate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Puromycin.
Doxacurium The therapeutic efficacy of Doxacurium can be increased when used in combination with Puromycin.
Mivacurium The therapeutic efficacy of Mivacurium can be increased when used in combination with Puromycin.
Decamethonium The therapeutic efficacy of Decamethonium can be increased when used in combination with Puromycin.
Metocurine The therapeutic efficacy of Metocurine can be increased when used in combination with Puromycin.
Pancuronium The therapeutic efficacy of Pancuronium can be increased when used in combination with Puromycin.
Pipecuronium The therapeutic efficacy of Pipecuronium can be increased when used in combination with Puromycin.
Vecuronium The therapeutic efficacy of Vecuronium can be increased when used in combination with Puromycin.
Rapacuronium The therapeutic efficacy of Rapacuronium can be increased when used in combination with Puromycin.
Pyrantel The therapeutic efficacy of Pyrantel can be increased when used in combination with Puromycin.
Neosaxitoxin The therapeutic efficacy of Neosaxitoxin can be increased when used in combination with Puromycin.
Atracurium The therapeutic efficacy of Atracurium can be increased when used in combination with Puromycin.
Gallamine The therapeutic efficacy of Gallamine can be increased when used in combination with Puromycin.
Alcuronium The therapeutic efficacy of Alcuronium can be increased when used in combination with Puromycin.
Tubocurarine The therapeutic efficacy of Tubocurarine can be increased when used in combination with Puromycin.
Carboplatin The risk or severity of ototoxicity and nephrotoxicity can be increased when Puromycin is combined with Carboplatin.
Foscarnet The risk or severity of nephrotoxicity can be increased when Puromycin is combined with Foscarnet.
Mannitol The risk or severity of nephrotoxicity can be increased when Mannitol is combined with Puromycin.
Tenofovir disoproxil Puromycin may increase the nephrotoxic activities of Tenofovir disoproxil.
Tenofovir alafenamide Puromycin may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir Puromycin may increase the nephrotoxic activities of Tenofovir.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Puromycin.
Zoledronic acid The risk or severity of nephrotoxicity and hypocalcemia can be increased when Puromycin is combined with Zoledronic acid.
Alendronic acid The risk or severity of nephrotoxicity and hypocalcemia can be increased when Puromycin is combined with Alendronic acid.
Ibandronate The risk or severity of nephrotoxicity and hypocalcemia can be increased when Puromycin is combined with Ibandronate.
Clodronic acid The risk or severity of nephrotoxicity and hypocalcemia can be increased when Puromycin is combined with Clodronic acid.
Risedronic acid The risk or severity of nephrotoxicity and hypocalcemia can be increased when Puromycin is combined with Risedronic acid.
Etidronic acid The risk or severity of nephrotoxicity and hypocalcemia can be increased when Puromycin is combined with Etidronic acid.
Incadronic acid The risk or severity of nephrotoxicity and hypocalcemia can be increased when Puromycin is combined with Incadronic acid.
Pamidronic acid The risk or severity of nephrotoxicity and hypocalcemia can be increased when Puromycin is combined with Pamidronic acid.
Tiludronic acid The risk or severity of nephrotoxicity and hypocalcemia can be increased when Puromycin is combined with Tiludronic acid.
Cyclosporine The risk or severity of nephrotoxicity can be increased when Cyclosporine is combined with Puromycin.
Icosapent The risk or severity of nephrotoxicity can be increased when Icosapent is combined with Puromycin.
Cefotiam The risk or severity of nephrotoxicity can be increased when Cefotiam is combined with Puromycin.
Mesalazine The risk or severity of nephrotoxicity can be increased when Mesalazine is combined with Puromycin.
Cefmenoxime The risk or severity of nephrotoxicity can be increased when Cefmenoxime is combined with Puromycin.
Cefmetazole The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Puromycin.
Indomethacin The risk or severity of nephrotoxicity can be increased when Indomethacin is combined with Puromycin.
Cidofovir The risk or severity of nephrotoxicity can be increased when Cidofovir is combined with Puromycin.
Triamterene The risk or severity of nephrotoxicity can be increased when Triamterene is combined with Puromycin.
Cefpiramide The risk or severity of nephrotoxicity can be increased when Cefpiramide is combined with Puromycin.
Ceftazidime The risk or severity of nephrotoxicity can be increased when Ceftazidime is combined with Puromycin.
Loracarbef The risk or severity of nephrotoxicity can be increased when Loracarbef is combined with Puromycin.
Framycetin The risk or severity of nephrotoxicity can be increased when Framycetin is combined with Puromycin.
Cefalotin The risk or severity of nephrotoxicity can be increased when Cefalotin is combined with Puromycin.
Nabumetone The risk or severity of nephrotoxicity can be increased when Nabumetone is combined with Puromycin.
Ketorolac The risk or severity of nephrotoxicity can be increased when Ketorolac is combined with Puromycin.
Tenoxicam The risk or severity of nephrotoxicity can be increased when Tenoxicam is combined with Puromycin.
Celecoxib The risk or severity of nephrotoxicity can be increased when Celecoxib is combined with Puromycin.
Cefotaxime The risk or severity of nephrotoxicity can be increased when Cefotaxime is combined with Puromycin.
Tolmetin The risk or severity of nephrotoxicity can be increased when Tolmetin is combined with Puromycin.
Rofecoxib The risk or severity of nephrotoxicity can be increased when Rofecoxib is combined with Puromycin.
Piroxicam The risk or severity of nephrotoxicity can be increased when Piroxicam is combined with Puromycin.
Methotrexate The risk or severity of nephrotoxicity can be increased when Methotrexate is combined with Puromycin.
Cephalexin The risk or severity of nephrotoxicity can be increased when Cephalexin is combined with Puromycin.
Fenoprofen The risk or severity of nephrotoxicity can be increased when Fenoprofen is combined with Puromycin.
Valaciclovir The risk or severity of nephrotoxicity can be increased when Valaciclovir is combined with Puromycin.
Valdecoxib The risk or severity of nephrotoxicity can be increased when Valdecoxib is combined with Puromycin.
Diclofenac The risk or severity of nephrotoxicity can be increased when Diclofenac is combined with Puromycin.
Sulindac The risk or severity of nephrotoxicity can be increased when Sulindac is combined with Puromycin.
Bacitracin The risk or severity of nephrotoxicity can be increased when Bacitracin is combined with Puromycin.
Amphotericin B The risk or severity of nephrotoxicity can be increased when Amphotericin B is combined with Puromycin.
Cephaloglycin The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Puromycin.
Flurbiprofen The risk or severity of nephrotoxicity can be increased when Flurbiprofen is combined with Puromycin.
Adefovir dipivoxil The risk or severity of nephrotoxicity can be increased when Adefovir dipivoxil is combined with Puromycin.
Pentamidine The risk or severity of nephrotoxicity can be increased when Pentamidine is combined with Puromycin.
Etodolac The risk or severity of nephrotoxicity can be increased when Etodolac is combined with Puromycin.
Mefenamic acid The risk or severity of nephrotoxicity can be increased when Mefenamic acid is combined with Puromycin.
Acyclovir The risk or severity of nephrotoxicity can be increased when Acyclovir is combined with Puromycin.
Naproxen The risk or severity of nephrotoxicity can be increased when Naproxen is combined with Puromycin.
Sulfasalazine The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Puromycin.
Phenylbutazone The risk or severity of nephrotoxicity can be increased when Phenylbutazone is combined with Puromycin.
Meloxicam The risk or severity of methemoglobinemia can be increased when Puromycin is combined with Meloxicam.
Carprofen The risk or severity of nephrotoxicity can be increased when Carprofen is combined with Puromycin.
Cefaclor The risk or severity of nephrotoxicity can be increased when Cefaclor is combined with Puromycin.
Diflunisal The risk or severity of nephrotoxicity can be increased when Diflunisal is combined with Puromycin.
Tacrolimus The risk or severity of nephrotoxicity can be increased when Tacrolimus is combined with Puromycin.
Ceforanide The risk or severity of nephrotoxicity can be increased when Ceforanide is combined with Puromycin.
Salicylic acid The risk or severity of nephrotoxicity can be increased when Salicylic acid is combined with Puromycin.
Meclofenamic acid The risk or severity of nephrotoxicity can be increased when Meclofenamic acid is combined with Puromycin.
Acetylsalicylic acid The risk or severity of nephrotoxicity can be increased when Acetylsalicylic acid is combined with Puromycin.
Oxaprozin The risk or severity of nephrotoxicity can be increased when Oxaprozin is combined with Puromycin.
Hydrochlorothiazide The risk or severity of nephrotoxicity can be increased when Hydrochlorothiazide is combined with Puromycin.
Ketoprofen The risk or severity of nephrotoxicity can be increased when Ketoprofen is combined with Puromycin.
Balsalazide The risk or severity of nephrotoxicity can be increased when Balsalazide is combined with Puromycin.
Ibuprofen The risk or severity of nephrotoxicity can be increased when Ibuprofen is combined with Puromycin.
Cefditoren The risk or severity of nephrotoxicity can be increased when Cefditoren is combined with Puromycin.
Atazanavir The risk or severity of nephrotoxicity can be increased when Atazanavir is combined with Puromycin.
Colistimethate The risk or severity of nephrotoxicity can be increased when Colistimethate is combined with Puromycin.
Cefuroxime The risk or severity of nephrotoxicity can be increased when Cefuroxime is combined with Puromycin.
Cefapirin The risk or severity of nephrotoxicity can be increased when Cefapirin is combined with Puromycin.
Cefadroxil The risk or severity of nephrotoxicity can be increased when Cefadroxil is combined with Puromycin.
Cefprozil The risk or severity of nephrotoxicity can be increased when Cefprozil is combined with Puromycin.
Ceftriaxone The risk or severity of nephrotoxicity can be increased when Ceftriaxone is combined with Puromycin.
Olsalazine The risk or severity of nephrotoxicity can be increased when Puromycin is combined with Olsalazine.

Target Protein

Ribosomal protein uL16-like RPL10L
Large ribosomal subunit protein uL13 RPL13A
Large ribosomal subunit protein uL14 RPL23
Large ribosomal subunit protein eL15 RPL15
Large ribosomal subunit protein eL19 RPL19
Large ribosomal subunit protein uL23 RPL23A
Probable ribosome biogenesis protein RLP24 RSL24D1
Ribosomal protein uL24-like RPL26L1
Large ribosomal subunit protein uL2 RPL8
Large ribosomal subunit protein eL37 RPL37
Large ribosomal subunit protein uL3 RPL3
Large ribosomal subunit protein uL5 RPL11
Leucyl/phenylalanyl-tRNA--protein transferase aat

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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