Fasudil

DB08162

small molecule investigational

Deskripsi

Fasudil has been investigated in Carotid Stenosis.

Struktur Molekul 2D

Berat 291.369
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

493 Data
Nicotine The risk or severity of adverse effects can be increased when Fasudil is combined with Nicotine.
Mecamylamine The risk or severity of adverse effects can be increased when Fasudil is combined with Mecamylamine.
Pentolinium The risk or severity of adverse effects can be increased when Fasudil is combined with Pentolinium.
Trimethaphan The risk or severity of adverse effects can be increased when Fasudil is combined with Trimethaphan.
Hexamethonium The risk or severity of adverse effects can be increased when Fasudil is combined with Hexamethonium.
Cyclopentamine The risk or severity of adverse effects can be increased when Fasudil is combined with Cyclopentamine.
Cimetidine The serum concentration of Fasudil can be increased when it is combined with Cimetidine.
Clopidogrel The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Fasudil.
Efavirenz The serum concentration of Fasudil can be decreased when it is combined with Efavirenz.
Phenytoin The serum concentration of Phenytoin can be increased when it is combined with Fasudil.
Fosphenytoin The serum concentration of Fosphenytoin can be increased when it is combined with Fasudil.
Melatonin The therapeutic efficacy of Fasudil can be decreased when used in combination with Melatonin.
Nafcillin The therapeutic efficacy of Fasudil can be decreased when used in combination with Nafcillin.
Nitroprusside Fasudil may increase the hypotensive activities of Nitroprusside.
Dantrolene The risk or severity of hyperkalemia can be increased when Dantrolene is combined with Fasudil.
Lithium citrate The risk or severity of adverse effects can be increased when Fasudil is combined with Lithium citrate.
Lithium carbonate The risk or severity of adverse effects can be increased when Fasudil is combined with Lithium carbonate.
Lithium hydroxide The risk or severity of adverse effects can be increased when Fasudil is combined with Lithium hydroxide.
Methotrexate The protein binding of Methotrexate can be increased when combined with Fasudil.
Boceprevir The serum concentration of Fasudil can be increased when it is combined with Boceprevir.
Ketoprofen The risk or severity of adverse effects can be increased when Ketoprofen is combined with Fasudil.
Dexketoprofen The risk or severity of adverse effects can be increased when Dexketoprofen is combined with Fasudil.
Dofetilide Dofetilide may increase the arrhythmogenic activities of Fasudil.
Isradipine Isradipine may increase the arrhythmogenic activities of Fasudil.
Lidocaine Lidocaine may increase the arrhythmogenic activities of Fasudil.
Ibutilide Ibutilide may increase the arrhythmogenic activities of Fasudil.
Diltiazem Diltiazem may increase the arrhythmogenic activities of Fasudil.
Trimethadione Trimethadione may increase the arrhythmogenic activities of Fasudil.
Mexiletine Mexiletine may increase the arrhythmogenic activities of Fasudil.
Amlodipine Amlodipine may increase the arrhythmogenic activities of Fasudil.
Nimodipine Nimodipine may increase the arrhythmogenic activities of Fasudil.
Nisoldipine Nisoldipine may increase the arrhythmogenic activities of Fasudil.
Hyoscyamine Hyoscyamine may increase the arrhythmogenic activities of Fasudil.
Lercanidipine Lercanidipine may increase the arrhythmogenic activities of Fasudil.
Lamotrigine Lamotrigine may increase the arrhythmogenic activities of Fasudil.
Cinnarizine Cinnarizine may increase the arrhythmogenic activities of Fasudil.
Atropine Atropine may increase the arrhythmogenic activities of Fasudil.
Ethosuximide Ethosuximide may increase the arrhythmogenic activities of Fasudil.
Adenosine Adenosine may increase the arrhythmogenic activities of Fasudil.
Losartan Losartan may increase the arrhythmogenic activities of Fasudil.
Moricizine Moricizine may increase the arrhythmogenic activities of Fasudil.
Levomenthol Levomenthol may increase the arrhythmogenic activities of Fasudil.
Loperamide Loperamide may increase the arrhythmogenic activities of Fasudil.
Zonisamide Zonisamide may increase the arrhythmogenic activities of Fasudil.
Levosimendan Levosimendan may increase the arrhythmogenic activities of Fasudil.
Procainamide Procainamide may increase the arrhythmogenic activities of Fasudil.
Nitrendipine Nitrendipine may increase the arrhythmogenic activities of Fasudil.
Tocainide Tocainide may increase the arrhythmogenic activities of Fasudil.
Perhexiline Perhexiline may increase the arrhythmogenic activities of Fasudil.
Bretylium Bretylium may increase the arrhythmogenic activities of Fasudil.
Flecainide Flecainide may increase the arrhythmogenic activities of Fasudil.
Encainide Encainide may increase the arrhythmogenic activities of Fasudil.
Bepridil Bepridil may increase the arrhythmogenic activities of Fasudil.
Mibefradil Mibefradil may increase the arrhythmogenic activities of Fasudil.
Ajmaline Ajmaline may increase the arrhythmogenic activities of Fasudil.
Aprindine Aprindine may increase the arrhythmogenic activities of Fasudil.
Nimesulide Nimesulide may increase the arrhythmogenic activities of Fasudil.
Prenylamine Prenylamine may increase the arrhythmogenic activities of Fasudil.
Cyclandelate Cyclandelate may increase the arrhythmogenic activities of Fasudil.
Flunarizine Flunarizine may increase the arrhythmogenic activities of Fasudil.
Fluspirilene Fluspirilene may increase the arrhythmogenic activities of Fasudil.
Clevidipine Clevidipine may increase the arrhythmogenic activities of Fasudil.
Azimilide Azimilide may increase the arrhythmogenic activities of Fasudil.
Methsuximide Methsuximide may increase the arrhythmogenic activities of Fasudil.
Seletracetam Seletracetam may increase the arrhythmogenic activities of Fasudil.
Nylidrin Nylidrin may increase the arrhythmogenic activities of Fasudil.
Tedisamil Tedisamil may increase the arrhythmogenic activities of Fasudil.
Vernakalant Vernakalant may increase the arrhythmogenic activities of Fasudil.
Ziconotide Ziconotide may increase the arrhythmogenic activities of Fasudil.
Dotarizine Dotarizine may increase the arrhythmogenic activities of Fasudil.
Cariporide Cariporide may increase the arrhythmogenic activities of Fasudil.
Xylometazoline Xylometazoline may increase the arrhythmogenic activities of Fasudil.
Nilvadipine Nilvadipine may increase the arrhythmogenic activities of Fasudil.
Sparteine Sparteine may increase the arrhythmogenic activities of Fasudil.
Tranilast Tranilast may increase the arrhythmogenic activities of Fasudil.
Carteolol Fasudil may increase the arrhythmogenic activities of Carteolol.
Metipranolol Fasudil may increase the arrhythmogenic activities of Metipranolol.
Agmatine Fasudil may increase the arrhythmogenic activities of Agmatine.
Fendiline Fasudil may increase the arrhythmogenic activities of Fendiline.
Eperisone Fasudil may increase the arrhythmogenic activities of Eperisone.
Trimebutine Fasudil may increase the arrhythmogenic activities of Trimebutine.
Pinaverium Fasudil may increase the arrhythmogenic activities of Pinaverium.
Nicorandil Fasudil may increase the arrhythmogenic activities of Nicorandil.
Melperone Fasudil may increase the arrhythmogenic activities of Melperone.
Barnidipine Fasudil may increase the arrhythmogenic activities of Barnidipine.
Aranidipine Fasudil may increase the arrhythmogenic activities of Aranidipine.
Azelnidipine Fasudil may increase the arrhythmogenic activities of Azelnidipine.
Benidipine Fasudil may increase the arrhythmogenic activities of Benidipine.
Cilnidipine Fasudil may increase the arrhythmogenic activities of Cilnidipine.
Darodipine Fasudil may increase the arrhythmogenic activities of Darodipine.
Efonidipine Fasudil may increase the arrhythmogenic activities of Efonidipine.
Lacidipine Fasudil may increase the arrhythmogenic activities of Lacidipine.
Manidipine Fasudil may increase the arrhythmogenic activities of Manidipine.
Niludipine Fasudil may increase the arrhythmogenic activities of Niludipine.
Tropisetron Fasudil may increase the arrhythmogenic activities of Tropisetron.
Carboxyamidotriazole Fasudil may increase the arrhythmogenic activities of Carboxyamidotriazole.
Naftopidil Fasudil may increase the arrhythmogenic activities of Naftopidil.
Tetrahydropalmatine Fasudil may increase the arrhythmogenic activities of Tetrahydropalmatine.
Vinpocetine Fasudil may increase the arrhythmogenic activities of Vinpocetine.
Simendan Fasudil may increase the arrhythmogenic activities of Simendan.

Target Protein

Rho-associated protein kinase 1 ROCK1
cAMP-dependent protein kinase inhibitor alpha PKIA
cAMP-dependent protein kinase catalytic subunit alpha PRKACA
Rho-associated protein kinase 2 ROCK2

Referensi & Sumber

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Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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