Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Denosumab | The risk or severity of adverse effects can be increased when Denosumab is combined with Wortmannin. |
| Etanercept | The risk or severity of adverse effects can be increased when Etanercept is combined with Wortmannin. |
| Peginterferon alfa-2a | The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Wortmannin. |
| Interferon alfa-n1 | The risk or severity of adverse effects can be increased when Interferon alfa-n1 is combined with Wortmannin. |
| Interferon alfa-n3 | The risk or severity of adverse effects can be increased when Interferon alfa-n3 is combined with Wortmannin. |
| Peginterferon alfa-2b | The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Wortmannin. |
| Anakinra | The risk or severity of adverse effects can be increased when Anakinra is combined with Wortmannin. |
| Interferon gamma-1b | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Wortmannin. |
| Interferon alfa-2a | The risk or severity of adverse effects can be increased when Interferon alfa-2a is combined with Wortmannin. |
| Aldesleukin | The risk or severity of adverse effects can be increased when Aldesleukin is combined with Wortmannin. |
| Adalimumab | The risk or severity of adverse effects can be increased when Adalimumab is combined with Wortmannin. |
| Gemtuzumab ozogamicin | The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Wortmannin. |
| Pegaspargase | The risk or severity of adverse effects can be increased when Pegaspargase is combined with Wortmannin. |
| Infliximab | The risk or severity of adverse effects can be increased when Infliximab is combined with Wortmannin. |
| Interferon beta-1b | The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Wortmannin. |
| Interferon alfacon-1 | The risk or severity of adverse effects can be increased when Interferon alfacon-1 is combined with Wortmannin. |
| Rituximab | The risk or severity of adverse effects can be increased when Rituximab is combined with Wortmannin. |
| Basiliximab | The risk or severity of adverse effects can be increased when Basiliximab is combined with Wortmannin. |
| Muromonab | The risk or severity of adverse effects can be increased when Muromonab is combined with Wortmannin. |
| Ibritumomab tiuxetan | The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Wortmannin. |
| Tositumomab | The risk or severity of adverse effects can be increased when Tositumomab is combined with Wortmannin. |
| Alemtuzumab | The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Wortmannin. |
| Alefacept | The risk or severity of adverse effects can be increased when Alefacept is combined with Wortmannin. |
| Efalizumab | The risk or severity of adverse effects can be increased when Efalizumab is combined with Wortmannin. |
| Antithymocyte immunoglobulin (rabbit) | The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Wortmannin. |
| Interferon alfa-2b | The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Wortmannin. |
| Daclizumab | The risk or severity of adverse effects can be increased when Daclizumab is combined with Wortmannin. |
| Phenylalanine | The risk or severity of adverse effects can be increased when Phenylalanine is combined with Wortmannin. |
| Flunisolide | The risk or severity of adverse effects can be increased when Flunisolide is combined with Wortmannin. |
| Bortezomib | The risk or severity of adverse effects can be increased when Bortezomib is combined with Wortmannin. |
| Cladribine | Wortmannin may increase the immunosuppressive activities of Cladribine. |
| Carmustine | The risk or severity of adverse effects can be increased when Carmustine is combined with Wortmannin. |
| Amsacrine | The risk or severity of adverse effects can be increased when Amsacrine is combined with Wortmannin. |
| Bleomycin | The risk or severity of adverse effects can be increased when Bleomycin is combined with Wortmannin. |
| Chlorambucil | The risk or severity of adverse effects can be increased when Chlorambucil is combined with Wortmannin. |
| Raltitrexed | The risk or severity of adverse effects can be increased when Raltitrexed is combined with Wortmannin. |
| Mitomycin | The risk or severity of adverse effects can be increased when Mitomycin is combined with Wortmannin. |
| Bexarotene | The risk or severity of adverse effects can be increased when Bexarotene is combined with Wortmannin. |
| Vindesine | The risk or severity of adverse effects can be increased when Vindesine is combined with Wortmannin. |
| Floxuridine | The risk or severity of adverse effects can be increased when Floxuridine is combined with Wortmannin. |
| Indomethacin | The risk or severity of adverse effects can be increased when Indomethacin is combined with Wortmannin. |
| Tioguanine | The risk or severity of adverse effects can be increased when Tioguanine is combined with Wortmannin. |
| Vinorelbine | The risk or severity of adverse effects can be increased when Vinorelbine is combined with Wortmannin. |
| Dexrazoxane | The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Wortmannin. |
| Beclomethasone dipropionate | The risk or severity of adverse effects can be increased when Beclomethasone dipropionate is combined with Wortmannin. |
| Sorafenib | The risk or severity of adverse effects can be increased when Sorafenib is combined with Wortmannin. |
| Streptozocin | The risk or severity of adverse effects can be increased when Streptozocin is combined with Wortmannin. |
| Trifluridine | The risk or severity of adverse effects can be increased when Trifluridine is combined with Wortmannin. |
| Gemcitabine | The risk or severity of adverse effects can be increased when Gemcitabine is combined with Wortmannin. |
| Betamethasone | The risk or severity of adverse effects can be increased when Betamethasone is combined with Wortmannin. |
| Teniposide | The risk or severity of adverse effects can be increased when Teniposide is combined with Wortmannin. |
| Epirubicin | The risk or severity of adverse effects can be increased when Epirubicin is combined with Wortmannin. |
| Chloramphenicol | The risk or severity of adverse effects can be increased when Chloramphenicol is combined with Wortmannin. |
| Lenalidomide | The risk or severity of adverse effects can be increased when Lenalidomide is combined with Wortmannin. |
| Altretamine | The risk or severity of adverse effects can be increased when Altretamine is combined with Wortmannin. |
| Zidovudine | The risk or severity of adverse effects can be increased when Zidovudine is combined with Wortmannin. |
| Cisplatin | The risk or severity of adverse effects can be increased when Cisplatin is combined with Wortmannin. |
| Oxaliplatin | The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Wortmannin. |
| Cyclophosphamide | The risk or severity of adverse effects can be increased when Cyclophosphamide is combined with Wortmannin. |
| Vincristine | The risk or severity of adverse effects can be increased when Vincristine is combined with Wortmannin. |
| Fluorouracil | The risk or severity of adverse effects can be increased when Fluorouracil is combined with Wortmannin. |
| Propylthiouracil | The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Wortmannin. |
| Pentostatin | The risk or severity of adverse effects can be increased when Pentostatin is combined with Wortmannin. |
| Methotrexate | The risk or severity of adverse effects can be increased when Methotrexate is combined with Wortmannin. |
| Carbamazepine | The risk or severity of adverse effects can be increased when Carbamazepine is combined with Wortmannin. |
| Vinblastine | The risk or severity of adverse effects can be increased when Vinblastine is combined with Wortmannin. |
| Fluticasone propionate | The risk or severity of adverse effects can be increased when Fluticasone propionate is combined with Wortmannin. |
| Fluocinolone acetonide | The risk or severity of adverse effects can be increased when Fluocinolone acetonide is combined with Wortmannin. |
| Linezolid | The risk or severity of adverse effects can be increased when Linezolid is combined with Wortmannin. |
| Imatinib | The risk or severity of adverse effects can be increased when Imatinib is combined with Wortmannin. |
| Triamcinolone | The risk or severity of adverse effects can be increased when Triamcinolone is combined with Wortmannin. |
| Clofarabine | The risk or severity of adverse effects can be increased when Clofarabine is combined with Wortmannin. |
| Prednisone | The risk or severity of adverse effects can be increased when Prednisone is combined with Wortmannin. |
| Pemetrexed | The risk or severity of adverse effects can be increased when Pemetrexed is combined with Wortmannin. |
| Fludrocortisone | The risk or severity of adverse effects can be increased when Fludrocortisone is combined with Wortmannin. |
| Mycophenolate mofetil | The risk or severity of adverse effects can be increased when Mycophenolate mofetil is combined with Wortmannin. |
| Daunorubicin | The risk or severity of adverse effects can be increased when Daunorubicin is combined with Wortmannin. |
| Irinotecan | The risk or severity of adverse effects can be increased when Irinotecan is combined with Wortmannin. |
| Methimazole | The risk or severity of adverse effects can be increased when Methimazole is combined with Wortmannin. |
| Etoposide | The risk or severity of adverse effects can be increased when Etoposide is combined with Wortmannin. |
| Sulfasalazine | The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Wortmannin. |
| Dacarbazine | The risk or severity of adverse effects can be increased when Dacarbazine is combined with Wortmannin. |
| Temozolomide | The risk or severity of adverse effects can be increased when Temozolomide is combined with Wortmannin. |
| Penicillamine | The risk or severity of adverse effects can be increased when Penicillamine is combined with Wortmannin. |
| Prednisolone | The risk or severity of adverse effects can be increased when Prednisolone is combined with Wortmannin. |
| Sirolimus | The risk or severity of adverse effects can be increased when Sirolimus is combined with Wortmannin. |
| Mechlorethamine | The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Wortmannin. |
| Azacitidine | The risk or severity of adverse effects can be increased when Azacitidine is combined with Wortmannin. |
| Carboplatin | The risk or severity of adverse effects can be increased when Carboplatin is combined with Wortmannin. |
| Methylprednisolone | The risk or severity of adverse effects can be increased when Methylprednisolone is combined with Wortmannin. |
| Dactinomycin | The risk or severity of adverse effects can be increased when Dactinomycin is combined with Wortmannin. |
| Cytarabine | The risk or severity of adverse effects can be increased when Cytarabine is combined with Wortmannin. |
| Azathioprine | The risk or severity of adverse effects can be increased when Azathioprine is combined with Wortmannin. |
| Doxorubicin | The risk or severity of adverse effects can be increased when Doxorubicin is combined with Wortmannin. |
| Hydroxyurea | The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Wortmannin. |
| Busulfan | The risk or severity of adverse effects can be increased when Busulfan is combined with Wortmannin. |
| Mycophenolic acid | The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Wortmannin. |
| Topotecan | The risk or severity of adverse effects can be increased when Topotecan is combined with Wortmannin. |
| Mercaptopurine | The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Wortmannin. |
| Melphalan | The risk or severity of adverse effects can be increased when Melphalan is combined with Wortmannin. |