Brefeldin A

DB07348

small molecule experimental

Deskripsi

A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.

Struktur Molekul 2D

Berat 280.3594
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

424 Data
Afatinib The serum concentration of Afatinib can be increased when it is combined with Brefeldin A.
Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Brefeldin A.
Brentuximab vedotin The serum concentration of Brentuximab vedotin can be increased when it is combined with Brefeldin A.
Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Brefeldin A.
Ledipasvir The serum concentration of Ledipasvir can be increased when it is combined with Brefeldin A.
Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Brefeldin A.
Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Brefeldin A.
Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Brefeldin A.
Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Brefeldin A.
Silodosin The excretion of Silodosin can be decreased when combined with Brefeldin A.
Topotecan The serum concentration of Topotecan can be increased when it is combined with Brefeldin A.
Eliglustat The metabolism of Eliglustat can be decreased when combined with Brefeldin A.
Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Brefeldin A.
Alfentanil The serum concentration of Alfentanil can be increased when it is combined with Brefeldin A.
Buspirone The metabolism of Buspirone can be decreased when combined with Brefeldin A.
Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Brefeldin A.
Cisapride The serum concentration of Cisapride can be increased when it is combined with Brefeldin A.
Disopyramide Brefeldin A may increase the QTc-prolonging activities of Disopyramide.
Estazolam The serum concentration of Estazolam can be increased when it is combined with Brefeldin A.
Everolimus The serum concentration of Everolimus can be increased when it is combined with Brefeldin A.
Quinine The serum concentration of Quinine can be increased when it is combined with Brefeldin A.
Quinidine The serum concentration of Quinidine can be increased when it is combined with Brefeldin A.
Repaglinide The serum concentration of Repaglinide can be increased when it is combined with Brefeldin A.
Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Brefeldin A.
Sirolimus The metabolism of Sirolimus can be decreased when combined with Brefeldin A.
Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Brefeldin A.
Terfenadine The serum concentration of Terfenadine can be increased when it is combined with Brefeldin A.
Triazolam The serum concentration of Triazolam can be increased when it is combined with Brefeldin A.
Cilostazol The metabolism of Cilostazol can be decreased when combined with Brefeldin A.
Colchicine The serum concentration of Colchicine can be increased when it is combined with Brefeldin A.
Iloperidone The metabolism of Iloperidone can be decreased when combined with Brefeldin A.
Retapamulin The metabolism of Retapamulin can be decreased when combined with Brefeldin A.
Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Brefeldin A.
Vardenafil The metabolism of Vardenafil can be decreased when combined with Brefeldin A.
Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Brefeldin A.
Zopiclone The metabolism of Zopiclone can be decreased when combined with Brefeldin A.
Lovastatin The metabolism of Lovastatin can be decreased when combined with Brefeldin A.
Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Brefeldin A.
Alprazolam The serum concentration of Alprazolam can be increased when it is combined with Brefeldin A.
Warfarin The serum concentration of Warfarin can be increased when it is combined with Brefeldin A.
Acenocoumarol The serum concentration of Acenocoumarol can be increased when it is combined with Brefeldin A.
(R)-warfarin The serum concentration of (R)-warfarin can be increased when it is combined with Brefeldin A.
R,S-Warfarin alcohol The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with Brefeldin A.
S,R-Warfarin alcohol The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with Brefeldin A.
(S)-Warfarin The serum concentration of (S)-Warfarin can be increased when it is combined with Brefeldin A.
Midazolam The serum concentration of Midazolam can be increased when it is combined with Brefeldin A.
Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Brefeldin A.
Telaprevir The serum concentration of Telaprevir can be increased when it is combined with Brefeldin A.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Brefeldin A.
Vincristine The excretion of Vincristine can be decreased when combined with Brefeldin A.
Vintafolide The serum concentration of Vintafolide can be increased when it is combined with Brefeldin A.
Vincamine The serum concentration of Vincamine can be increased when it is combined with Brefeldin A.
Acetyldigitoxin The serum concentration of Acetyldigitoxin can be increased when it is combined with Brefeldin A.
Deslanoside The serum concentration of Deslanoside can be increased when it is combined with Brefeldin A.
Ouabain The serum concentration of Ouabain can be increased when it is combined with Brefeldin A.
Oleandrin The serum concentration of Oleandrin can be increased when it is combined with Brefeldin A.
Cymarin The serum concentration of Cymarin can be increased when it is combined with Brefeldin A.
Proscillaridin The serum concentration of Proscillaridin can be increased when it is combined with Brefeldin A.
Lanatoside C The serum concentration of Lanatoside C can be increased when it is combined with Brefeldin A.
Gitoformate The serum concentration of Gitoformate can be increased when it is combined with Brefeldin A.
Peruvoside The serum concentration of Peruvoside can be increased when it is combined with Brefeldin A.
Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Brefeldin A.
Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Brefeldin A.
Dicoumarol The serum concentration of Dicoumarol can be increased when it is combined with Brefeldin A.
Phenindione The serum concentration of Phenindione can be increased when it is combined with Brefeldin A.
Coumarin The serum concentration of Coumarin can be increased when it is combined with Brefeldin A.
Tioclomarol The serum concentration of Tioclomarol can be increased when it is combined with Brefeldin A.
Ethyl biscoumacetate The serum concentration of Ethyl biscoumacetate can be increased when it is combined with Brefeldin A.
Diphenadione The serum concentration of Diphenadione can be increased when it is combined with Brefeldin A.
4-hydroxycoumarin The serum concentration of 4-hydroxycoumarin can be increased when it is combined with Brefeldin A.
Fluindione The serum concentration of Fluindione can be increased when it is combined with Brefeldin A.
Clorindione The serum concentration of Clorindione can be increased when it is combined with Brefeldin A.
Oxtriphylline The metabolism of Oxtriphylline can be decreased when combined with Brefeldin A.
Doxofylline The metabolism of Doxofylline can be decreased when combined with Brefeldin A.
Bamifylline The metabolism of Bamifylline can be decreased when combined with Brefeldin A.
Acefylline The metabolism of Acefylline can be decreased when combined with Brefeldin A.
Bufylline The metabolism of Bufylline can be decreased when combined with Brefeldin A.
Fenethylline The metabolism of Fenethylline can be decreased when combined with Brefeldin A.
Proxyphylline The metabolism of Proxyphylline can be decreased when combined with Brefeldin A.
Bromotheophylline The metabolism of Bromotheophylline can be decreased when combined with Brefeldin A.
Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Brefeldin A.
8-azaguanine The metabolism of 8-azaguanine can be decreased when combined with Brefeldin A.
7,9-Dimethylguanine The metabolism of 7,9-Dimethylguanine can be decreased when combined with Brefeldin A.
Xanthine The metabolism of Xanthine can be decreased when combined with Brefeldin A.
7-Deazaguanine The metabolism of 7-Deazaguanine can be decreased when combined with Brefeldin A.
Guanine The metabolism of Guanine can be decreased when combined with Brefeldin A.
9-Methylguanine The metabolism of 9-Methylguanine can be decreased when combined with Brefeldin A.
Peldesine The metabolism of Peldesine can be decreased when combined with Brefeldin A.
Hypoxanthine The metabolism of Hypoxanthine can be decreased when combined with Brefeldin A.
9-Deazaguanine The metabolism of 9-Deazaguanine can be decreased when combined with Brefeldin A.
Valomaciclovir The metabolism of Valomaciclovir can be decreased when combined with Brefeldin A.
3-isobutyl-1-methyl-7H-xanthine The metabolism of 3-isobutyl-1-methyl-7H-xanthine can be decreased when combined with Brefeldin A.
Uric acid The metabolism of Uric acid can be decreased when combined with Brefeldin A.
6-O-benzylguanine The metabolism of 6-O-benzylguanine can be decreased when combined with Brefeldin A.
Lisofylline The metabolism of Lisofylline can be decreased when combined with Brefeldin A.
Lobucavir The metabolism of Lobucavir can be decreased when combined with Brefeldin A.
Cafedrine The metabolism of Cafedrine can be decreased when combined with Brefeldin A.
Theodrenaline The metabolism of Theodrenaline can be decreased when combined with Brefeldin A.
Etamiphylline The metabolism of Etamiphylline can be decreased when combined with Brefeldin A.
Pentifylline The metabolism of Pentifylline can be decreased when combined with Brefeldin A.

Target Protein

Cytohesin-2 CYTH2
ADP-ribosylation factor 1 ARF1

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 0
Belum ada data produk/brand untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field produk/brand.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul