Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood pressure. This drug has been discontinued by the FDA.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Alfuzosin | Alfuzosin may increase the hypotensive activities of Pinacidil. |
| Amifostine | Pinacidil may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Pinacidil. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Pinacidil. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Pinacidil. |
| Obinutuzumab | Pinacidil may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Pinacidil. |
| Rituximab | Pinacidil may increase the hypotensive activities of Rituximab. |
| Desmopressin | Desmopressin may decrease the antihypertensive activities of Pinacidil. |
| Midodrine | Midodrine may decrease the antihypertensive activities of Pinacidil. |
| Isoetharine | Isoetharine may decrease the antihypertensive activities of Pinacidil. |
| Atomoxetine | Atomoxetine may decrease the antihypertensive activities of Pinacidil. |
| Etomidate | Etomidate may decrease the antihypertensive activities of Pinacidil. |
| Zolmitriptan | Zolmitriptan may decrease the antihypertensive activities of Pinacidil. |
| Protriptyline | Protriptyline may decrease the antihypertensive activities of Pinacidil. |
| Norepinephrine | Norepinephrine may decrease the antihypertensive activities of Pinacidil. |
| Phenylephrine | Phenylephrine may decrease the antihypertensive activities of Pinacidil. |
| Phenylpropanolamine | Phenylpropanolamine may decrease the antihypertensive activities of Pinacidil. |
| Droperidol | Droperidol may decrease the antihypertensive activities of Pinacidil. |
| Amoxapine | Amoxapine may decrease the antihypertensive activities of Pinacidil. |
| Doxapram | Doxapram may decrease the antihypertensive activities of Pinacidil. |
| Atropine | Atropine may decrease the antihypertensive activities of Pinacidil. |
| Metaraminol | Metaraminol may decrease the antihypertensive activities of Pinacidil. |
| Sumatriptan | Sumatriptan may decrease the antihypertensive activities of Pinacidil. |
| Nicergoline | Nicergoline may decrease the antihypertensive activities of Pinacidil. |
| Methoxamine | Methoxamine may decrease the antihypertensive activities of Pinacidil. |
| Propiomazine | Propiomazine may decrease the antihypertensive activities of Pinacidil. |
| Orciprenaline | Orciprenaline may decrease the antihypertensive activities of Pinacidil. |
| Phenmetrazine | Phenmetrazine may decrease the antihypertensive activities of Pinacidil. |
| Trifluoperazine | Trifluoperazine may decrease the antihypertensive activities of Pinacidil. |
| Dobutamine | Dobutamine may decrease the antihypertensive activities of Pinacidil. |
| Pseudoephedrine | Pseudoephedrine may decrease the antihypertensive activities of Pinacidil. |
| Ritodrine | Ritodrine may decrease the antihypertensive activities of Pinacidil. |
| Terbutaline | Terbutaline may decrease the antihypertensive activities of Pinacidil. |
| Flupentixol | Flupentixol may decrease the antihypertensive activities of Pinacidil. |
| Bitolterol | Bitolterol may decrease the antihypertensive activities of Pinacidil. |
| Diethylpropion | Diethylpropion may decrease the antihypertensive activities of Pinacidil. |
| Naratriptan | Naratriptan may decrease the antihypertensive activities of Pinacidil. |
| Rizatriptan | Rizatriptan may decrease the antihypertensive activities of Pinacidil. |
| Formoterol | Formoterol may decrease the antihypertensive activities of Pinacidil. |
| Dopamine | Dopamine may decrease the antihypertensive activities of Pinacidil. |
| Frovatriptan | Frovatriptan may decrease the antihypertensive activities of Pinacidil. |
| Isoprenaline | Isoprenaline may decrease the antihypertensive activities of Pinacidil. |
| Arbutamine | Arbutamine may decrease the antihypertensive activities of Pinacidil. |
| Lisdexamfetamine | Lisdexamfetamine may decrease the antihypertensive activities of Pinacidil. |
| Arformoterol | Arformoterol may decrease the antihypertensive activities of Pinacidil. |
| Fenoterol | Fenoterol may decrease the antihypertensive activities of Pinacidil. |
| Pirbuterol | Pirbuterol may decrease the antihypertensive activities of Pinacidil. |
| Ephedra sinica root | Ephedra sinica root may decrease the antihypertensive activities of Pinacidil. |
| Ephedrine | Ephedrine may decrease the antihypertensive activities of Pinacidil. |
| Mephentermine | Mephentermine may decrease the antihypertensive activities of Pinacidil. |
| Procaterol | Procaterol may decrease the antihypertensive activities of Pinacidil. |
| Methotrimeprazine | Methotrimeprazine may decrease the antihypertensive activities of Pinacidil. |
| Clenbuterol | Clenbuterol may decrease the antihypertensive activities of Pinacidil. |
| Bambuterol | Bambuterol may decrease the antihypertensive activities of Pinacidil. |
| MMDA | MMDA may decrease the antihypertensive activities of Pinacidil. |
| Midomafetamine | Midomafetamine may decrease the antihypertensive activities of Pinacidil. |
| 2,5-Dimethoxy-4-ethylamphetamine | 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Pinacidil. |
| 4-Methoxyamphetamine | 4-Methoxyamphetamine may decrease the antihypertensive activities of Pinacidil. |
| 4-Bromo-2,5-dimethoxyamphetamine | 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Pinacidil. |
| Tenamfetamine | Tenamfetamine may decrease the antihypertensive activities of Pinacidil. |
| Chlorphentermine | Chlorphentermine may decrease the antihypertensive activities of Pinacidil. |
| Dextroamphetamine | Dextroamphetamine may decrease the antihypertensive activities of Pinacidil. |
| Metamfetamine | Metamfetamine may decrease the antihypertensive activities of Pinacidil. |
| Phendimetrazine | Phendimetrazine may decrease the antihypertensive activities of Pinacidil. |
| Periciazine | Periciazine may decrease the antihypertensive activities of Pinacidil. |
| Acepromazine | Acepromazine may decrease the antihypertensive activities of Pinacidil. |
| Thioproperazine | Thioproperazine may decrease the antihypertensive activities of Pinacidil. |
| Epicaptopril | Epicaptopril may decrease the antihypertensive activities of Pinacidil. |
| 1-benzylimidazole | 1-benzylimidazole may decrease the antihypertensive activities of Pinacidil. |
| Amineptine | Amineptine may decrease the antihypertensive activities of Pinacidil. |
| Amibegron | Amibegron may decrease the antihypertensive activities of Pinacidil. |
| Naluzotan | Naluzotan may decrease the antihypertensive activities of Pinacidil. |
| Pizotifen | Pizotifen may decrease the antihypertensive activities of Pinacidil. |
| Solabegron | Solabegron may decrease the antihypertensive activities of Pinacidil. |
| Droxidopa | Droxidopa may decrease the antihypertensive activities of Pinacidil. |
| Esmirtazapine | Esmirtazapine may decrease the antihypertensive activities of Pinacidil. |
| Nitrous oxide | Nitrous oxide may decrease the antihypertensive activities of Pinacidil. |
| Xylometazoline | Xylometazoline may decrease the antihypertensive activities of Pinacidil. |
| Isometheptene | Isometheptene may decrease the antihypertensive activities of Pinacidil. |
| Levonordefrin | Levonordefrin may decrease the antihypertensive activities of Pinacidil. |
| Naphazoline | Naphazoline may decrease the antihypertensive activities of Pinacidil. |
| Saralasin | Saralasin may decrease the antihypertensive activities of Pinacidil. |
| Tetryzoline | Tetryzoline may decrease the antihypertensive activities of Pinacidil. |
| Cinitapride | Cinitapride may decrease the antihypertensive activities of Pinacidil. |
| Tyramine | Tyramine may decrease the antihypertensive activities of Pinacidil. |
| Adrafinil | Adrafinil may decrease the antihypertensive activities of Pinacidil. |
| Ifenprodil | Ifenprodil may decrease the antihypertensive activities of Pinacidil. |
| Hexoprenaline | Hexoprenaline may decrease the antihypertensive activities of Pinacidil. |
| Etilefrine | Etilefrine may decrease the antihypertensive activities of Pinacidil. |
| Dimetacrine | Dimetacrine may decrease the antihypertensive activities of Pinacidil. |
| Butriptyline | Butriptyline may decrease the antihypertensive activities of Pinacidil. |
| Olodaterol | Olodaterol may decrease the antihypertensive activities of Pinacidil. |
| Dosulepin | Dosulepin may decrease the antihypertensive activities of Pinacidil. |
| Cirazoline | Cirazoline may decrease the antihypertensive activities of Pinacidil. |
| Synephrine | Synephrine may decrease the antihypertensive activities of Pinacidil. |
| Moxisylyte | Moxisylyte may decrease the antihypertensive activities of Pinacidil. |
| Oxaprotiline | Oxaprotiline may decrease the antihypertensive activities of Pinacidil. |
| Iofetamine I-123 | Iofetamine I-123 may decrease the antihypertensive activities of Pinacidil. |
| Racepinephrine | Racepinephrine may decrease the antihypertensive activities of Pinacidil. |