Seproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an antidepressant but development was never completed and the drug was never marketed.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Cilostazol | The serum concentration of Cilostazol can be increased when it is combined with Seproxetine. |
| Cyproheptadine | The therapeutic efficacy of Seproxetine can be decreased when used in combination with Cyproheptadine. |
| Desmopressin | The risk or severity of hyponatremia can be increased when Seproxetine is combined with Desmopressin. |
| Ioflupane I-123 | Seproxetine may decrease effectiveness of Ioflupane I-123 as a diagnostic agent. |
| Linezolid | The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Seproxetine. |
| Metyrosine | The risk or severity of extrapyramidal symptoms can be increased when Metyrosine is combined with Seproxetine. |
| Pimozide | The risk or severity of QTc prolongation can be increased when Seproxetine is combined with Pimozide. |
| Buprenorphine | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Seproxetine. |
| Dronabinol | The serum concentration of Dronabinol can be increased when it is combined with Seproxetine. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Seproxetine. |
| Hydrocodone | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Seproxetine. |
| Magnesium sulfate | The therapeutic efficacy of Seproxetine can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Seproxetine. |
| Mirtazapine | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Seproxetine. |
| Orphenadrine | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Seproxetine. |
| Pramipexole | Seproxetine may increase the sedative activities of Pramipexole. |
| Ropinirole | Seproxetine may increase the sedative activities of Ropinirole. |
| Rotigotine | Seproxetine may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Seproxetine. |
| Sodium oxybate | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Seproxetine. |
| Thalidomide | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Seproxetine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Brexpiprazole | The metabolism of Brexpiprazole can be decreased when combined with Seproxetine. |
| Eliglustat | The metabolism of Eliglustat can be decreased when combined with Seproxetine. |
| Everolimus | The metabolism of Everolimus can be decreased when combined with Seproxetine. |
| Flibanserin | The metabolism of Flibanserin can be decreased when combined with Seproxetine. |
| Ibrutinib | The metabolism of Ibrutinib can be decreased when combined with Seproxetine. |
| Ivabradine | The metabolism of Ivabradine can be decreased when combined with Seproxetine. |
| Ivacaftor | The metabolism of Ivacaftor can be decreased when combined with Seproxetine. |
| Lurasidone | The metabolism of Lurasidone can be decreased when combined with Seproxetine. |
| Naloxegol | The metabolism of Naloxegol can be decreased when combined with Seproxetine. |
| Olaparib | The metabolism of Olaparib can be decreased when combined with Seproxetine. |
| Ranolazine | The metabolism of Ranolazine can be decreased when combined with Seproxetine. |
| Sonidegib | The metabolism of Sonidegib can be decreased when combined with Seproxetine. |
| Avanafil | The metabolism of Avanafil can be decreased when combined with Seproxetine. |
| Eplerenone | The metabolism of Eplerenone can be decreased when combined with Seproxetine. |
| Colchicine | The metabolism of Colchicine can be decreased when combined with Seproxetine. |
| Fentanyl | The risk or severity of serotonin syndrome can be increased when Fentanyl is combined with Seproxetine. |
| Iloperidone | The metabolism of Iloperidone can be decreased when combined with Seproxetine. |
| Retapamulin | The metabolism of Retapamulin can be decreased when combined with Seproxetine. |
| Tofacitinib | The metabolism of Tofacitinib can be decreased when combined with Seproxetine. |
| Vardenafil | The metabolism of Vardenafil can be decreased when combined with Seproxetine. |
| Zopiclone | The metabolism of Zopiclone can be decreased when combined with Seproxetine. |
| Lovastatin | The metabolism of Lovastatin can be decreased when combined with Seproxetine. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Seproxetine. |
| Alfuzosin | The metabolism of Alfuzosin can be decreased when combined with Seproxetine. |
| Alprazolam | The metabolism of Alprazolam can be decreased when combined with Seproxetine. |
| Warfarin | The serum concentration of Warfarin can be increased when it is combined with Seproxetine. |
| Acenocoumarol | The serum concentration of Acenocoumarol can be increased when it is combined with Seproxetine. |
| (R)-warfarin | The serum concentration of (R)-warfarin can be increased when it is combined with Seproxetine. |
| R,S-Warfarin alcohol | The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with Seproxetine. |
| S,R-Warfarin alcohol | The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with Seproxetine. |
| (S)-Warfarin | The serum concentration of (S)-Warfarin can be increased when it is combined with Seproxetine. |
| Midazolam | The serum concentration of Midazolam can be increased when it is combined with Seproxetine. |
| Tacrolimus | The serum concentration of Tacrolimus can be increased when it is combined with Seproxetine. |
| Atorvastatin | The metabolism of Atorvastatin can be decreased when combined with Seproxetine. |
| Tedizolid phosphate | The risk or severity of serotonin syndrome can be increased when Tedizolid phosphate is combined with Seproxetine. |
| Naltrexone | The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Seproxetine. |
| Bezitramide | The risk or severity of serotonin syndrome can be increased when Bezitramide is combined with Seproxetine. |
| Eluxadoline | The risk or severity of serotonin syndrome can be increased when Eluxadoline is combined with Seproxetine. |
| Morphine | The risk or severity of serotonin syndrome can be increased when Morphine is combined with Seproxetine. |
| Codeine | The risk or severity of serotonin syndrome can be increased when Codeine is combined with Seproxetine. |
| Hydromorphone | The risk or severity of serotonin syndrome can be increased when Hydromorphone is combined with Seproxetine. |
| Meperidine | The risk or severity of serotonin syndrome can be increased when Meperidine is combined with Seproxetine. |
| Oxycodone | The risk or severity of serotonin syndrome can be increased when Oxycodone is combined with Seproxetine. |
| Butorphanol | The risk or severity of serotonin syndrome can be increased when Butorphanol is combined with Seproxetine. |
| Dextropropoxyphene | The risk or severity of serotonin syndrome can be increased when Dextropropoxyphene is combined with Seproxetine. |
| Pentazocine | The risk or severity of serotonin syndrome can be increased when Pentazocine is combined with Seproxetine. |
| Sufentanil | The risk or severity of serotonin syndrome can be increased when Sufentanil is combined with Seproxetine. |
| Nalbuphine | The risk or severity of serotonin syndrome can be increased when Nalbuphine is combined with Seproxetine. |
| Levorphanol | The risk or severity of serotonin syndrome can be increased when Levorphanol is combined with Seproxetine. |
| Remifentanil | The risk or severity of serotonin syndrome can be increased when Remifentanil is combined with Seproxetine. |
| Diphenoxylate | The risk or severity of serotonin syndrome can be increased when Diphenoxylate is combined with Seproxetine. |
| Oxymorphone | The risk or severity of serotonin syndrome can be increased when Oxymorphone is combined with Seproxetine. |
| Dezocine | The risk or severity of serotonin syndrome can be increased when Dezocine is combined with Seproxetine. |
| Levacetylmethadol | The risk or severity of serotonin syndrome can be increased when Levacetylmethadol is combined with Seproxetine. |
| Methadyl acetate | The risk or severity of serotonin syndrome can be increased when Methadyl acetate is combined with Seproxetine. |
| Dihydroetorphine | The risk or severity of serotonin syndrome can be increased when Dihydroetorphine is combined with Seproxetine. |
| Diamorphine | The risk or severity of serotonin syndrome can be increased when Diamorphine is combined with Seproxetine. |
| Ethylmorphine | The risk or severity of serotonin syndrome can be increased when Ethylmorphine is combined with Seproxetine. |
| Etorphine | The risk or severity of serotonin syndrome can be increased when Etorphine is combined with Seproxetine. |
| Dextromoramide | The risk or severity of serotonin syndrome can be increased when Dextromoramide is combined with Seproxetine. |
| Desomorphine | The risk or severity of serotonin syndrome can be increased when Desomorphine is combined with Seproxetine. |
| Carfentanil | The risk or severity of serotonin syndrome can be increased when Carfentanil is combined with Seproxetine. |
| Dihydrocodeine | The risk or severity of serotonin syndrome can be increased when Dihydrocodeine is combined with Seproxetine. |
| Alphacetylmethadol | The risk or severity of serotonin syndrome can be increased when Alphacetylmethadol is combined with Seproxetine. |
| Dihydromorphine | The risk or severity of serotonin syndrome can be increased when Dihydromorphine is combined with Seproxetine. |
| Ketobemidone | The risk or severity of serotonin syndrome can be increased when Ketobemidone is combined with Seproxetine. |
| DPDPE | The risk or severity of serotonin syndrome can be increased when DPDPE is combined with Seproxetine. |
| Lofentanil | The risk or severity of serotonin syndrome can be increased when Lofentanil is combined with Seproxetine. |
| Opium | The risk or severity of serotonin syndrome can be increased when Opium is combined with Seproxetine. |
| Normethadone | The risk or severity of serotonin syndrome can be increased when Normethadone is combined with Seproxetine. |