Gimatecan

DB06721

small molecule investigational

Deskripsi

Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.

Struktur Molekul 2D

Berat 447.491
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

121 Data
Apalutamide The serum concentration of Gimatecan can be decreased when it is combined with Apalutamide.
Cyclosporine The excretion of Gimatecan can be decreased when combined with Cyclosporine.
Valsartan The excretion of Gimatecan can be decreased when combined with Valsartan.
Troglitazone The excretion of Gimatecan can be decreased when combined with Troglitazone.
Erythromycin The excretion of Gimatecan can be decreased when combined with Erythromycin.
Sildenafil The excretion of Gimatecan can be decreased when combined with Sildenafil.
Reserpine The excretion of Gimatecan can be decreased when combined with Reserpine.
Pantoprazole The excretion of Gimatecan can be decreased when combined with Pantoprazole.
Nelfinavir The excretion of Gimatecan can be decreased when combined with Nelfinavir.
Indinavir The excretion of Gimatecan can be decreased when combined with Indinavir.
Diethylstilbestrol The excretion of Gimatecan can be decreased when combined with Diethylstilbestrol.
Conjugated estrogens The excretion of Gimatecan can be decreased when combined with Conjugated estrogens.
Indomethacin The excretion of Gimatecan can be decreased when combined with Indomethacin.
Digoxin The excretion of Gimatecan can be decreased when combined with Digoxin.
Beclomethasone dipropionate The excretion of Gimatecan can be decreased when combined with Beclomethasone dipropionate.
Progesterone The excretion of Gimatecan can be decreased when combined with Progesterone.
Rosiglitazone The excretion of Gimatecan can be decreased when combined with Rosiglitazone.
Cerivastatin The excretion of Gimatecan can be decreased when combined with Cerivastatin.
Quinine The excretion of Gimatecan can be decreased when combined with Quinine.
Ritonavir The excretion of Gimatecan can be decreased when combined with Ritonavir.
Caspofungin The excretion of Gimatecan can be decreased when combined with Caspofungin.
Vincristine The excretion of Gimatecan can be decreased when combined with Vincristine.
Vinblastine The excretion of Gimatecan can be decreased when combined with Vinblastine.
Levocarnitine The excretion of Gimatecan can be decreased when combined with Levocarnitine.
Diclofenac The excretion of Gimatecan can be decreased when combined with Diclofenac.
Fluticasone propionate The excretion of Gimatecan can be decreased when combined with Fluticasone propionate.
Ivermectin The excretion of Gimatecan can be decreased when combined with Ivermectin.
Nicardipine The excretion of Gimatecan can be decreased when combined with Nicardipine.
Simvastatin The excretion of Gimatecan can be decreased when combined with Simvastatin.
Nystatin The excretion of Gimatecan can be decreased when combined with Nystatin.
Amprenavir The excretion of Gimatecan can be decreased when combined with Amprenavir.
Irinotecan The excretion of Gimatecan can be decreased when combined with Irinotecan.
Roxithromycin The excretion of Gimatecan can be decreased when combined with Roxithromycin.
Estradiol The excretion of Gimatecan can be decreased when combined with Estradiol.
Sulfasalazine The excretion of Gimatecan can be decreased when combined with Sulfasalazine.
Mifepristone The excretion of Gimatecan can be decreased when combined with Mifepristone.
Tacrolimus The excretion of Gimatecan can be decreased when combined with Tacrolimus.
Sirolimus The excretion of Gimatecan can be decreased when combined with Sirolimus.
Quinidine The excretion of Gimatecan can be decreased when combined with Quinidine.
Tipranavir The excretion of Gimatecan can be decreased when combined with Tipranavir.
Dipyridamole The excretion of Gimatecan can be decreased when combined with Dipyridamole.
Telithromycin The excretion of Gimatecan can be decreased when combined with Telithromycin.
Ketoconazole The excretion of Gimatecan can be decreased when combined with Ketoconazole.
Novobiocin The excretion of Gimatecan can be decreased when combined with Novobiocin.
Atazanavir The excretion of Gimatecan can be decreased when combined with Atazanavir.
Atorvastatin The excretion of Gimatecan can be decreased when combined with Atorvastatin.
Ouabain The excretion of Gimatecan can be decreased when combined with Ouabain.
Fluvastatin The excretion of Gimatecan can be decreased when combined with Fluvastatin.
Rosuvastatin The excretion of Gimatecan can be decreased when combined with Rosuvastatin.
Saquinavir The excretion of Gimatecan can be decreased when combined with Saquinavir.
Gemfibrozil The excretion of Gimatecan can be decreased when combined with Gemfibrozil.
Darunavir The excretion of Gimatecan can be decreased when combined with Darunavir.
Bezafibrate The excretion of Gimatecan can be decreased when combined with Bezafibrate.
Everolimus The excretion of Gimatecan can be decreased when combined with Everolimus.
Lopinavir The excretion of Gimatecan can be decreased when combined with Lopinavir.
Genistein The excretion of Gimatecan can be decreased when combined with Genistein.
Hyperforin The excretion of Gimatecan can be decreased when combined with Hyperforin.
Cholic Acid The excretion of Gimatecan can be increased when combined with Cholic Acid.
Fusidic acid The excretion of Gimatecan can be decreased when combined with Fusidic acid.
Quercetin The excretion of Gimatecan can be decreased when combined with Quercetin.
Taurocholic acid The excretion of Gimatecan can be increased when combined with Taurocholic acid.
Posizolid The excretion of Gimatecan can be decreased when combined with Posizolid.
Nilotinib The excretion of Gimatecan can be decreased when combined with Nilotinib.
Telaprevir The excretion of Gimatecan can be decreased when combined with Telaprevir.
Dovitinib The excretion of Gimatecan can be decreased when combined with Dovitinib.
Acetylcysteine The excretion of Gimatecan can be decreased when combined with Acetylcysteine.
Eltrombopag The excretion of Gimatecan can be decreased when combined with Eltrombopag.
Simeprevir The excretion of Gimatecan can be decreased when combined with Simeprevir.
Pazopanib The excretion of Gimatecan can be decreased when combined with Pazopanib.
Axitinib The excretion of Gimatecan can be decreased when combined with Axitinib.
Cholecystokinin The excretion of Gimatecan can be decreased when combined with Cholecystokinin.
Rilpivirine The excretion of Gimatecan can be decreased when combined with Rilpivirine.
Teriflunomide The excretion of Gimatecan can be decreased when combined with Teriflunomide.
Dabrafenib The excretion of Gimatecan can be decreased when combined with Dabrafenib.
Idelalisib The excretion of Gimatecan can be decreased when combined with Idelalisib.
Cobicistat The excretion of Gimatecan can be decreased when combined with Cobicistat.
Lenvatinib The excretion of Gimatecan can be decreased when combined with Lenvatinib.
Daclatasvir The excretion of Gimatecan can be decreased when combined with Daclatasvir.
Lobeglitazone The excretion of Gimatecan can be decreased when combined with Lobeglitazone.
Eluxadoline The excretion of Gimatecan can be decreased when combined with Eluxadoline.
Sacubitril The excretion of Gimatecan can be decreased when combined with Sacubitril.
Paritaprevir The excretion of Gimatecan can be decreased when combined with Paritaprevir.
Silibinin The excretion of Gimatecan can be decreased when combined with Silibinin.
Venetoclax The excretion of Gimatecan can be decreased when combined with Venetoclax.
Asunaprevir The excretion of Gimatecan can be decreased when combined with Asunaprevir.
Velpatasvir The excretion of Gimatecan can be decreased when combined with Velpatasvir.
Valspodar The excretion of Gimatecan can be decreased when combined with Valspodar.
Voxilaprevir The excretion of Gimatecan can be decreased when combined with Voxilaprevir.
Benzbromarone The excretion of Gimatecan can be decreased when combined with Benzbromarone.
Fluticasone The excretion of Gimatecan can be decreased when combined with Fluticasone.
Enasidenib The excretion of Gimatecan can be decreased when combined with Enasidenib.
Pibrentasvir The excretion of Gimatecan can be decreased when combined with Pibrentasvir.
Glecaprevir The excretion of Gimatecan can be decreased when combined with Glecaprevir.
Candesartan The excretion of Gimatecan can be decreased when combined with Candesartan.
Estradiol acetate The excretion of Gimatecan can be decreased when combined with Estradiol acetate.
Estradiol benzoate The excretion of Gimatecan can be decreased when combined with Estradiol benzoate.
Estradiol cypionate The excretion of Gimatecan can be decreased when combined with Estradiol cypionate.
Estradiol dienanthate The excretion of Gimatecan can be decreased when combined with Estradiol dienanthate.
Estradiol valerate The excretion of Gimatecan can be decreased when combined with Estradiol valerate.
Pexidartinib The excretion of Gimatecan can be decreased when combined with Pexidartinib.

Target Protein

DNA topoisomerase 1 TOP1

Referensi & Sumber

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Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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