Norelgestromin

DB06713

small molecule approved investigational

Deskripsi

Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.

Struktur Molekul 2D

Berat 327.468
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

478 Data
Aprepitant The serum concentration of Norelgestromin can be decreased when it is combined with Aprepitant.
Exenatide Exenatide can cause a decrease in the absorption of Norelgestromin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Thalidomide Norelgestromin may increase the thrombogenic activities of Thalidomide.
Ulipristal The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Ulipristal.
Tranexamic acid Norelgestromin may increase the thrombogenic activities of Tranexamic acid.
Clobazam The serum concentration of Norelgestromin can be decreased when it is combined with Clobazam.
Griseofulvin The metabolism of Norelgestromin can be increased when combined with Griseofulvin.
Tixocortol The serum concentration of Tixocortol can be increased when it is combined with Norelgestromin.
Fluocortin The serum concentration of Fluocortin can be increased when it is combined with Norelgestromin.
Fluperolone The serum concentration of Fluperolone can be increased when it is combined with Norelgestromin.
Fluclorolone The serum concentration of Fluclorolone can be increased when it is combined with Norelgestromin.
Flunisolide The serum concentration of Flunisolide can be increased when it is combined with Norelgestromin.
Beclomethasone dipropionate The serum concentration of Beclomethasone dipropionate can be increased when it is combined with Norelgestromin.
Betamethasone The serum concentration of Betamethasone can be increased when it is combined with Norelgestromin.
Fluocinolone acetonide The serum concentration of Fluocinolone acetonide can be increased when it is combined with Norelgestromin.
Triamcinolone The serum concentration of Triamcinolone can be increased when it is combined with Norelgestromin.
Prednisone The serum concentration of Prednisone can be increased when it is combined with Norelgestromin.
Hydrocortisone The serum concentration of Hydrocortisone can be increased when it is combined with Norelgestromin.
Prednisolone The serum concentration of Prednisolone can be increased when it is combined with Norelgestromin.
Methylprednisolone The serum concentration of Methylprednisolone can be increased when it is combined with Norelgestromin.
Corticotropin The serum concentration of Corticotropin can be increased when it is combined with Norelgestromin.
Cortisone acetate The serum concentration of Cortisone acetate can be increased when it is combined with Norelgestromin.
Fluprednidene The serum concentration of Fluprednidene can be increased when it is combined with Norelgestromin.
Meprednisone The serum concentration of Meprednisone can be increased when it is combined with Norelgestromin.
Dexamethasone isonicotinate The serum concentration of Dexamethasone isonicotinate can be increased when it is combined with Norelgestromin.
Deflazacort The serum concentration of Deflazacort can be increased when it is combined with Norelgestromin.
Cortivazol The serum concentration of Cortivazol can be increased when it is combined with Norelgestromin.
Prednylidene The serum concentration of Prednylidene can be increased when it is combined with Norelgestromin.
Cloprednol The serum concentration of Cloprednol can be increased when it is combined with Norelgestromin.
Mometasone furoate The serum concentration of Mometasone furoate can be increased when it is combined with Norelgestromin.
Hydrocortisone acetate The serum concentration of Hydrocortisone acetate can be increased when it is combined with Norelgestromin.
Hydrocortisone succinate The serum concentration of Hydrocortisone succinate can be increased when it is combined with Norelgestromin.
Prednisolone phosphate The serum concentration of Prednisolone phosphate can be increased when it is combined with Norelgestromin.
Prednisolone hemisuccinate The serum concentration of Prednisolone hemisuccinate can be increased when it is combined with Norelgestromin.
Methylprednisolone hemisuccinate The serum concentration of Methylprednisolone hemisuccinate can be increased when it is combined with Norelgestromin.
Prednisone acetate The serum concentration of Prednisone acetate can be increased when it is combined with Norelgestromin.
Clocortolone acetate The serum concentration of Clocortolone acetate can be increased when it is combined with Norelgestromin.
Melengestrol acetate The serum concentration of Melengestrol acetate can be increased when it is combined with Norelgestromin.
Betamethasone phosphate The serum concentration of Betamethasone phosphate can be increased when it is combined with Norelgestromin.
Cortisone The serum concentration of Cortisone can be increased when it is combined with Norelgestromin.
Fluticasone propionate The serum concentration of Fluticasone propionate can be increased when it is combined with Norelgestromin.
Fludrocortisone The serum concentration of Fludrocortisone can be increased when it is combined with Norelgestromin.
Trilostane The serum concentration of Trilostane can be increased when it is combined with Norelgestromin.
Budesonide The serum concentration of Budesonide can be increased when it is combined with Norelgestromin.
Dexamethasone The serum concentration of Dexamethasone can be increased when it is combined with Norelgestromin.
Paramethasone The serum concentration of Paramethasone can be increased when it is combined with Norelgestromin.
Ciclesonide The serum concentration of Ciclesonide can be increased when it is combined with Norelgestromin.
Aldosterone The serum concentration of Aldosterone can be increased when it is combined with Norelgestromin.
Fluticasone furoate The serum concentration of Fluticasone furoate can be increased when it is combined with Norelgestromin.
Fluprednisolone The serum concentration of Fluprednisolone can be increased when it is combined with Norelgestromin.
Melengestrol The serum concentration of Melengestrol can be increased when it is combined with Norelgestromin.
Fluticasone The serum concentration of Fluticasone can be increased when it is combined with Norelgestromin.
Hydrocortisone cypionate The serum concentration of Hydrocortisone cypionate can be increased when it is combined with Norelgestromin.
Clobetasol propionate The serum concentration of Clobetasol propionate can be increased when it is combined with Norelgestromin.
Fluocinonide The serum concentration of Fluocinonide can be increased when it is combined with Norelgestromin.
Hydrocortisone butyrate The serum concentration of Hydrocortisone butyrate can be increased when it is combined with Norelgestromin.
Desoximetasone The serum concentration of Desoximetasone can be increased when it is combined with Norelgestromin.
Mometasone The serum concentration of Mometasone can be increased when it is combined with Norelgestromin.
Fluocortolone The serum concentration of Fluocortolone can be increased when it is combined with Norelgestromin.
Prednisolone acetate The serum concentration of Prednisolone acetate can be increased when it is combined with Norelgestromin.
Fluorometholone The serum concentration of Fluorometholone can be increased when it is combined with Norelgestromin.
Difluocortolone The serum concentration of Difluocortolone can be increased when it is combined with Norelgestromin.
Flumethasone The serum concentration of Flumethasone can be increased when it is combined with Norelgestromin.
Methylprednisolone aceponate The serum concentration of Methylprednisolone aceponate can be increased when it is combined with Norelgestromin.
Bosentan The serum concentration of Norelgestromin can be decreased when it is combined with Bosentan.
Carbamazepine The serum concentration of Norelgestromin can be decreased when it is combined with Carbamazepine.
Piperacillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Piperacillin.
Ampicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Ampicillin.
Phenoxymethylpenicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Phenoxymethylpenicillin.
Carbenicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Carbenicillin.
Oxacillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Oxacillin.
Hetacillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Hetacillin.
Benzylpenicilloyl polylysine The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Benzylpenicilloyl polylysine.
Mezlocillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Mezlocillin.
Cyclacillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Cyclacillin.
Benzylpenicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Benzylpenicillin.
Amoxicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Amoxicillin.
Azlocillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Azlocillin.
Cloxacillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Cloxacillin.
Amdinocillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Amdinocillin.
Bacampicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Bacampicillin.
Meticillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Meticillin.
Pivampicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Pivampicillin.
Pivmecillinam The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Pivmecillinam.
Ticarcillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Ticarcillin.
Azidocillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Azidocillin.
Carindacillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Carindacillin.
Procaine benzylpenicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Procaine benzylpenicillin.
Sultamicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Sultamicillin.
Temocillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Temocillin.
Epicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Epicillin.
Pheneticillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Pheneticillin.
Carfecillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Carfecillin.
Propicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Propicillin.
Clometocillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Clometocillin.
Sulbenicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Sulbenicillin.
Penamecillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Penamecillin.
Talampicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Talampicillin.
Aspoxicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Aspoxicillin.
Metampicillin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Metampicillin.

Target Protein

Progesterone receptor PGR
Albumin ALB
Androgen receptor AR

Referensi & Sumber

Synthesis reference: Zoltan Tuba, Sandor Maho, Gyorgy Keseru, Jozsef Kozma, Janos Horvath, Gabor Balogh, "Process of making isomers of norelgestromin and methods using the same." U.S. Patent US20050032764, issued February 10, 2005.
Artikel (PubMed)
  • PMID: 15966567
    Goa KL, Warner GT, Easthope SE: Transdermal ethinylestradiol/norelgestromin: a review of its use in hormonal contraception. Treat Endocrinol. 2003;2(3):191-206.
  • PMID: 11499185
    Henzl MR: Norgestimate. From the laboratory to three clinical indications. J Reprod Med. 2001 Jul;46(7):647-61.
  • PMID: 11697756
    Abrams LS, Skee DM, Wong FA, Anderson NJ, Leese PT: Pharmacokinetics of norelgestromin and ethinyl estradiol from two consecutive contraceptive patches. J Clin Pharmacol. 2001 Nov;41(11):1232-7.

Contoh Produk & Brand

Produk: 16 • International brands: 0
Produk
  • Evra
    Patch, extended release • - • Transdermal • Canada • Approved
  • Evra
    Patch • - • Transdermal • EU • Approved
  • Evra
    Patch • - • Transdermal • EU • Approved
  • Evra
    Patch • - • Transdermal • EU • Approved
  • Evra -(6/0.75)
    Patch, extended release • - • Transdermal • Canada • Approved
  • Norelgestromin and Ethinly Estradiol
    Patch • - • Transdermal • US • Generic • Approved
  • Norelgestromin and Ethinyl Estradiol
    Patch • - • Transdermal • US • Generic • Approved
  • Norelgestromin and Ethinyl Estradiol
    Patch • - • Transdermal • US • Generic • Approved
Menampilkan 8 dari 16 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul