Adipiplon

DB06579

small molecule investigational

Deskripsi

Adipiplon is an nonbenzodiazepine anxiolytic developed by Neurogen Corporation. It is known by the standardized identifier NG2-73.

Struktur Molekul 2D

Berat 351.389
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

664 Data
Buprenorphine Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Hydrocodone Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Magnesium sulfate The therapeutic efficacy of Adipiplon can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Adipiplon may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Mirtazapine Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Orphenadrine Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Pramipexole Adipiplon may increase the sedative activities of Pramipexole.
Ropinirole Adipiplon may increase the sedative activities of Ropinirole.
Rotigotine Adipiplon may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Adipiplon.
Sodium oxybate Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Thalidomide Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Yohimbine The therapeutic efficacy of Adipiplon can be increased when used in combination with Yohimbine.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Adipiplon.
Ethanol Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Adipiplon may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Zimelidine The risk or severity of adverse effects can be increased when Adipiplon is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Adipiplon is combined with Dapoxetine.
Seproxetine The risk or severity of adverse effects can be increased when Adipiplon is combined with Seproxetine.
Fluvoxamine The risk or severity of adverse effects can be increased when Adipiplon is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Adipiplon is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Adipiplon is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Adipiplon is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Adipiplon is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Adipiplon is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Adipiplon is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Adipiplon is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Adipiplon is combined with Escitalopram.
Milnacipran The risk or severity of adverse effects can be increased when Adipiplon is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Adipiplon is combined with Desvenlafaxine.
Levomilnacipran The risk or severity of adverse effects can be increased when Adipiplon is combined with Levomilnacipran.
Indalpine The risk or severity of adverse effects can be increased when Adipiplon is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Adipiplon is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Adipiplon is combined with Alaproclate.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Adipiplon.
Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with Adipiplon.
Zopiclone The risk or severity of adverse effects can be increased when Adipiplon is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Adipiplon.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Adipiplon.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Adipiplon.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Adipiplon.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Adipiplon.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Adipiplon.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Adipiplon.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Adipiplon.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Adipiplon.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Adipiplon.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Adipiplon.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Adipiplon.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Adipiplon.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Adipiplon.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Adipiplon.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Adipiplon.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Adipiplon.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Adipiplon.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Adipiplon.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Adipiplon.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Adipiplon.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Adipiplon.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Adipiplon.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Adipiplon.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Adipiplon.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Adipiplon.
Thiethylperazine The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Adipiplon.
Palonosetron The risk or severity of CNS depression can be increased when Palonosetron is combined with Adipiplon.
Dexbrompheniramine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Adipiplon.
Metocurine iodide The risk or severity of CNS depression can be increased when Metocurine iodide is combined with Adipiplon.
Secobarbital The risk or severity of CNS depression can be increased when Secobarbital is combined with Adipiplon.
Methocarbamol The risk or severity of CNS depression can be increased when Methocarbamol is combined with Adipiplon.
Triprolidine The risk or severity of CNS depression can be increased when Triprolidine is combined with Adipiplon.
Meperidine The risk or severity of CNS depression can be increased when Meperidine is combined with Adipiplon.
Metharbital The risk or severity of CNS depression can be increased when Metharbital is combined with Adipiplon.
Quinine The risk or severity of CNS depression can be increased when Quinine is combined with Adipiplon.
Methohexital The risk or severity of CNS depression can be increased when Methohexital is combined with Adipiplon.
Gallamine triethiodide The risk or severity of CNS depression can be increased when Gallamine triethiodide is combined with Adipiplon.
Entacapone The risk or severity of CNS depression can be increased when Entacapone is combined with Adipiplon.
Oxycodone The risk or severity of CNS depression can be increased when Oxycodone is combined with Adipiplon.
Dextromethorphan The risk or severity of CNS depression can be increased when Dextromethorphan is combined with Adipiplon.
Mephenytoin The risk or severity of CNS depression can be increased when Mephenytoin is combined with Adipiplon.
Cisatracurium The risk or severity of CNS depression can be increased when Cisatracurium is combined with Adipiplon.
Fenfluramine The risk or severity of CNS depression can be increased when Fenfluramine is combined with Adipiplon.
Mazindol The risk or severity of CNS depression can be increased when Mazindol is combined with Adipiplon.
Fluticasone propionate The risk or severity of CNS depression can be increased when Fluticasone propionate is combined with Adipiplon.
Lisuride The risk or severity of CNS depression can be increased when Lisuride is combined with Adipiplon.
Ethosuximide The risk or severity of CNS depression can be increased when Ethosuximide is combined with Adipiplon.
Thiopental The risk or severity of CNS depression can be increased when Thiopental is combined with Adipiplon.
Cisapride The risk or severity of CNS depression can be increased when Cisapride is combined with Adipiplon.

Target Protein

GABA(A) Receptor Benzodiazepine Binding Site GABRA1
Gamma-aminobutyric acid receptor subunit alpha-3 GABRA3

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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