Bivatuzumab

DB06550

biotech investigational

Deskripsi

Bivatuzumab (previously BIWA 4) is a humanized monoclonal antibody against CD44 v6. A31688,A31689

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

373 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Bivatuzumab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Bivatuzumab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Bivatuzumab.
Estrone Estrone may increase the thrombogenic activities of Bivatuzumab.
Estradiol Estradiol may increase the thrombogenic activities of Bivatuzumab.
Dienestrol Dienestrol may increase the thrombogenic activities of Bivatuzumab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Bivatuzumab.
Mestranol Mestranol may increase the thrombogenic activities of Bivatuzumab.
Estriol Estriol may increase the thrombogenic activities of Bivatuzumab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Bivatuzumab.
Quinestrol Quinestrol may increase the thrombogenic activities of Bivatuzumab.
Hexestrol Hexestrol may increase the thrombogenic activities of Bivatuzumab.
Tibolone Tibolone may increase the thrombogenic activities of Bivatuzumab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Bivatuzumab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Bivatuzumab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Bivatuzumab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Bivatuzumab.
Zeranol Zeranol may increase the thrombogenic activities of Bivatuzumab.
Equol Equol may increase the thrombogenic activities of Bivatuzumab.
Promestriene Promestriene may increase the thrombogenic activities of Bivatuzumab.
Methallenestril Methallenestril may increase the thrombogenic activities of Bivatuzumab.
Epimestrol Epimestrol may increase the thrombogenic activities of Bivatuzumab.
Moxestrol Moxestrol may increase the thrombogenic activities of Bivatuzumab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Bivatuzumab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Bivatuzumab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Bivatuzumab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Bivatuzumab.
Biochanin A Biochanin A may increase the thrombogenic activities of Bivatuzumab.
Formononetin Formononetin may increase the thrombogenic activities of Bivatuzumab.
Estetrol Estetrol may increase the thrombogenic activities of Bivatuzumab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Bivatuzumab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Bivatuzumab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Bivatuzumab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Bivatuzumab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Bivatuzumab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Bivatuzumab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Bivatuzumab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Bivatuzumab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Bivatuzumab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Bivatuzumab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Bivatuzumab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Bivatuzumab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Bivatuzumab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Bivatuzumab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Bivatuzumab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Bivatuzumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Bivatuzumab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Bivatuzumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Bivatuzumab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Bivatuzumab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Bivatuzumab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Bivatuzumab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Bivatuzumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Bivatuzumab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Bivatuzumab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Bivatuzumab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Bivatuzumab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Bivatuzumab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Bivatuzumab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Bivatuzumab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Bivatuzumab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Bivatuzumab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Bivatuzumab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Bivatuzumab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Bivatuzumab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Bivatuzumab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Bivatuzumab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Bivatuzumab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Bivatuzumab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Bivatuzumab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Bivatuzumab.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Bivatuzumab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Bivatuzumab.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Bivatuzumab.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Bivatuzumab.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Bivatuzumab.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Bivatuzumab.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Bivatuzumab.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Bivatuzumab.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with Bivatuzumab.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with Bivatuzumab.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Bivatuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with Bivatuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with Bivatuzumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Bivatuzumab.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with Bivatuzumab.
TNX-901 The risk or severity of adverse effects can be increased when TNX-901 is combined with Bivatuzumab.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Bivatuzumab.
RI 624 The risk or severity of adverse effects can be increased when RI 624 is combined with Bivatuzumab.
Stamulumab The risk or severity of adverse effects can be increased when MYO-029 is combined with Bivatuzumab.
CT-011 The risk or severity of adverse effects can be increased when CT-011 is combined with Bivatuzumab.
Leronlimab The risk or severity of adverse effects can be increased when Leronlimab is combined with Bivatuzumab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Bivatuzumab.
Olaratumab The risk or severity of adverse effects can be increased when Olaratumab is combined with Bivatuzumab.
IPH 2101 The risk or severity of adverse effects can be increased when IPH 2101 is combined with Bivatuzumab.
TB-402 The risk or severity of adverse effects can be increased when TB-402 is combined with Bivatuzumab.
Caplacizumab The risk or severity of adverse effects can be increased when Caplacizumab is combined with Bivatuzumab.
IMC-1C11 The risk or severity of adverse effects can be increased when IMC-1C11 is combined with Bivatuzumab.
Eldelumab The risk or severity of adverse effects can be increased when Eldelumab is combined with Bivatuzumab.
Lumiliximab The risk or severity of adverse effects can be increased when Lumiliximab is combined with Bivatuzumab.

Target Protein

CD44 antigen CD44

Referensi & Sumber

Artikel (PubMed)
  • PMID: 14530488
    Postema EJ, Borjesson PK, Buijs WC, Roos JC, Marres HA, Boerman OC, de Bree R, Lang M, Munzert G, van Dongen GA, Oyen WJ: Dosimetric analysis of radioimmunotherapy with 186Re-labeled bivatuzumab in patients with head and neck cancer. J Nucl Med. 2003 Oct;44(10):1690-9.
  • PMID: 14506195
    Borjesson PK, Postema EJ, Roos JC, Colnot DR, Marres HA, van Schie MH, Stehle G, de Bree R, Snow GB, Oyen WJ, van Dongen GA: Phase I therapy study with (186)Re-labeled humanized monoclonal antibody BIWA 4 (bivatuzumab) in patients with head and neck squamous cell carcinoma. Clin Cancer Res. 2003 Sep 1;9(10 Pt 2):3961S-72S.

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