Sibrotuzumab

DB06474

biotech investigational

Deskripsi

Sibrotuzumab is a humanized monoclonal antibody directed against fibroblast activation protein (FAP). It is used to treat cancer.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

373 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Sibrotuzumab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Sibrotuzumab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Sibrotuzumab.
Estrone Estrone may increase the thrombogenic activities of Sibrotuzumab.
Estradiol Estradiol may increase the thrombogenic activities of Sibrotuzumab.
Dienestrol Dienestrol may increase the thrombogenic activities of Sibrotuzumab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Sibrotuzumab.
Mestranol Mestranol may increase the thrombogenic activities of Sibrotuzumab.
Estriol Estriol may increase the thrombogenic activities of Sibrotuzumab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Sibrotuzumab.
Quinestrol Quinestrol may increase the thrombogenic activities of Sibrotuzumab.
Hexestrol Hexestrol may increase the thrombogenic activities of Sibrotuzumab.
Tibolone Tibolone may increase the thrombogenic activities of Sibrotuzumab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Sibrotuzumab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Sibrotuzumab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Sibrotuzumab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Sibrotuzumab.
Zeranol Zeranol may increase the thrombogenic activities of Sibrotuzumab.
Equol Equol may increase the thrombogenic activities of Sibrotuzumab.
Promestriene Promestriene may increase the thrombogenic activities of Sibrotuzumab.
Methallenestril Methallenestril may increase the thrombogenic activities of Sibrotuzumab.
Epimestrol Epimestrol may increase the thrombogenic activities of Sibrotuzumab.
Moxestrol Moxestrol may increase the thrombogenic activities of Sibrotuzumab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Sibrotuzumab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Sibrotuzumab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Sibrotuzumab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Sibrotuzumab.
Biochanin A Biochanin A may increase the thrombogenic activities of Sibrotuzumab.
Formononetin Formononetin may increase the thrombogenic activities of Sibrotuzumab.
Estetrol Estetrol may increase the thrombogenic activities of Sibrotuzumab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Sibrotuzumab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Sibrotuzumab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Sibrotuzumab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Sibrotuzumab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Sibrotuzumab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Sibrotuzumab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Sibrotuzumab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Sibrotuzumab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Sibrotuzumab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Sibrotuzumab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Sibrotuzumab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Sibrotuzumab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Sibrotuzumab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Sibrotuzumab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Sibrotuzumab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Sibrotuzumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Sibrotuzumab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Sibrotuzumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Sibrotuzumab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Sibrotuzumab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Sibrotuzumab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Sibrotuzumab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Sibrotuzumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Sibrotuzumab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Sibrotuzumab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Sibrotuzumab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Sibrotuzumab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Sibrotuzumab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Sibrotuzumab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Sibrotuzumab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Sibrotuzumab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Sibrotuzumab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Sibrotuzumab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Sibrotuzumab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Sibrotuzumab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Sibrotuzumab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Sibrotuzumab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Sibrotuzumab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Sibrotuzumab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Sibrotuzumab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Sibrotuzumab.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Sibrotuzumab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Sibrotuzumab.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Sibrotuzumab.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Sibrotuzumab.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Sibrotuzumab.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Sibrotuzumab.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Sibrotuzumab.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Sibrotuzumab.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with Sibrotuzumab.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with Sibrotuzumab.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Sibrotuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with Sibrotuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with Sibrotuzumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Sibrotuzumab.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with Sibrotuzumab.
TNX-901 The risk or severity of adverse effects can be increased when TNX-901 is combined with Sibrotuzumab.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Sibrotuzumab.
RI 624 The risk or severity of adverse effects can be increased when RI 624 is combined with Sibrotuzumab.
Stamulumab The risk or severity of adverse effects can be increased when MYO-029 is combined with Sibrotuzumab.
CT-011 The risk or severity of adverse effects can be increased when CT-011 is combined with Sibrotuzumab.
Leronlimab The risk or severity of adverse effects can be increased when Leronlimab is combined with Sibrotuzumab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Sibrotuzumab.
Olaratumab The risk or severity of adverse effects can be increased when Olaratumab is combined with Sibrotuzumab.
IPH 2101 The risk or severity of adverse effects can be increased when IPH 2101 is combined with Sibrotuzumab.
TB-402 The risk or severity of adverse effects can be increased when TB-402 is combined with Sibrotuzumab.
Caplacizumab The risk or severity of adverse effects can be increased when Caplacizumab is combined with Sibrotuzumab.
IMC-1C11 The risk or severity of adverse effects can be increased when IMC-1C11 is combined with Sibrotuzumab.
Eldelumab The risk or severity of adverse effects can be increased when Eldelumab is combined with Sibrotuzumab.
Lumiliximab The risk or severity of adverse effects can be increased when Lumiliximab is combined with Sibrotuzumab.

Target Protein

Prolyl endopeptidase FAP FAP

Referensi & Sumber

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