Apolizumab

DB06467

biotech investigational

Deskripsi

Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

373 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Apolizumab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Apolizumab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Apolizumab.
Estrone Estrone may increase the thrombogenic activities of Apolizumab.
Estradiol Estradiol may increase the thrombogenic activities of Apolizumab.
Dienestrol Dienestrol may increase the thrombogenic activities of Apolizumab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Apolizumab.
Mestranol Mestranol may increase the thrombogenic activities of Apolizumab.
Estriol Estriol may increase the thrombogenic activities of Apolizumab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Apolizumab.
Quinestrol Quinestrol may increase the thrombogenic activities of Apolizumab.
Hexestrol Hexestrol may increase the thrombogenic activities of Apolizumab.
Tibolone Tibolone may increase the thrombogenic activities of Apolizumab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Apolizumab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Apolizumab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Apolizumab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Apolizumab.
Zeranol Zeranol may increase the thrombogenic activities of Apolizumab.
Equol Equol may increase the thrombogenic activities of Apolizumab.
Promestriene Promestriene may increase the thrombogenic activities of Apolizumab.
Methallenestril Methallenestril may increase the thrombogenic activities of Apolizumab.
Epimestrol Epimestrol may increase the thrombogenic activities of Apolizumab.
Moxestrol Moxestrol may increase the thrombogenic activities of Apolizumab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Apolizumab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Apolizumab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Apolizumab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Apolizumab.
Biochanin A Biochanin A may increase the thrombogenic activities of Apolizumab.
Formononetin Formononetin may increase the thrombogenic activities of Apolizumab.
Estetrol Estetrol may increase the thrombogenic activities of Apolizumab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Apolizumab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Apolizumab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Apolizumab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Apolizumab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Apolizumab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Apolizumab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Apolizumab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Apolizumab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Apolizumab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Apolizumab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Apolizumab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Apolizumab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Apolizumab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Apolizumab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Apolizumab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Apolizumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Apolizumab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Apolizumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Apolizumab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Apolizumab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Apolizumab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Apolizumab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Apolizumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Apolizumab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Apolizumab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Apolizumab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Apolizumab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Apolizumab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Apolizumab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Apolizumab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Apolizumab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Apolizumab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Apolizumab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Apolizumab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Apolizumab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Apolizumab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Apolizumab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Apolizumab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Apolizumab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Apolizumab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Apolizumab.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Apolizumab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Apolizumab.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Apolizumab.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Apolizumab.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Apolizumab.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Apolizumab.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Apolizumab.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Apolizumab.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with Apolizumab.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with Apolizumab.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Apolizumab.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with Apolizumab.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with Apolizumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Apolizumab.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with Apolizumab.
TNX-901 The risk or severity of adverse effects can be increased when TNX-901 is combined with Apolizumab.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Apolizumab.
RI 624 The risk or severity of adverse effects can be increased when RI 624 is combined with Apolizumab.
Stamulumab The risk or severity of adverse effects can be increased when MYO-029 is combined with Apolizumab.
CT-011 The risk or severity of adverse effects can be increased when CT-011 is combined with Apolizumab.
Leronlimab The risk or severity of adverse effects can be increased when Leronlimab is combined with Apolizumab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Apolizumab.
Olaratumab The risk or severity of adverse effects can be increased when Olaratumab is combined with Apolizumab.
IPH 2101 The risk or severity of adverse effects can be increased when IPH 2101 is combined with Apolizumab.
TB-402 The risk or severity of adverse effects can be increased when TB-402 is combined with Apolizumab.
Caplacizumab The risk or severity of adverse effects can be increased when Caplacizumab is combined with Apolizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when IMC-1C11 is combined with Apolizumab.
Eldelumab The risk or severity of adverse effects can be increased when Eldelumab is combined with Apolizumab.
Lumiliximab The risk or severity of adverse effects can be increased when Lumiliximab is combined with Apolizumab.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 17071489
    Rech J, Repp R, Rech D, Stockmeyer B, Dechant M, Niedobitek G, Gramatzki M, Valerius T: A humanized HLA-DR antibody (hu1D10, apolizumab) in combination with granulocyte colony-stimulating factor (filgrastim) for the treatment of non-Hodgkin's lymphoma: a pilot study. Leuk Lymphoma. 2006 Oct;47(10):2147-54.

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