Tucidinostat

DB06334

small molecule investigational

Deskripsi

Struktur Molekul 2D

Berat 390.418
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

404 Data
Ivabradine Ivabradine may increase the QTc-prolonging activities of Tucidinostat.
Vorinostat The risk or severity of gastrointestinal bleeding and thrombocytopenia can be increased when Tucidinostat is combined with Vorinostat.
Dofetilide The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Dofetilide.
Citalopram The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Citalopram.
Anagrelide The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Anagrelide.
Disopyramide The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Disopyramide.
Clemastine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Clemastine.
Ibutilide The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Ibutilide.
Valproic acid The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Valproic acid.
Terfenadine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Terfenadine.
Grepafloxacin The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Grepafloxacin.
Quinine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Quinine.
Sotalol The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Sotalol.
Erlotinib The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Erlotinib.
Toremifene The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Toremifene.
Cisapride The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Cisapride.
Imatinib The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Imatinib.
Astemizole The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Astemizole.
Thioridazine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Thioridazine.
Trovafloxacin The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Trovafloxacin.
Mifepristone The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Mifepristone.
Cocaine The risk or severity of methemoglobinemia can be increased when Tucidinostat is combined with Cocaine.
Quinidine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Quinidine.
Procainamide The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Procainamide.
Pimozide The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Pimozide.
Amiodarone The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Amiodarone.
Arsenic trioxide The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Arsenic trioxide.
Escitalopram The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Escitalopram.
Domperidone The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Domperidone.
Sparfloxacin The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Sparfloxacin.
Halofantrine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Halofantrine.
Bepridil The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Bepridil.
Paliperidone The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Paliperidone.
Lithium cation The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Lithium cation.
Temafloxacin The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Temafloxacin.
Zuclopenthixol The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Zuclopenthixol.
Tetrabenazine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Tetrabenazine.
Dronedarone The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Dronedarone.
Nilotinib The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Nilotinib.
Iloperidone The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Iloperidone.
Vandetanib The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Vandetanib.
Romidepsin The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Romidepsin.
Asenapine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Asenapine.
Artemether The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Artemether.
Lumefantrine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Lumefantrine.
Vemurafenib The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Vemurafenib.
Eliglustat The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Eliglustat.
Ribociclib The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Tucidinostat.
Glasdegib The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Glasdegib.
Deutetrabenazine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Deutetrabenazine.
Macimorelin The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Macimorelin.
Terodiline The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Terodiline.
Leuprolide The risk or severity of QTc prolongation can be increased when Leuprolide is combined with Tucidinostat.
Goserelin The risk or severity of QTc prolongation can be increased when Goserelin is combined with Tucidinostat.
Erythromycin The risk or severity of QTc prolongation can be increased when Erythromycin is combined with Tucidinostat.
Azithromycin The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Tucidinostat.
Moxifloxacin The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Tucidinostat.
Ranolazine The risk or severity of QTc prolongation can be increased when Ranolazine is combined with Tucidinostat.
Sulfisoxazole The risk or severity of QTc prolongation can be increased when Sulfisoxazole is combined with Tucidinostat.
Amitriptyline The risk or severity of QTc prolongation can be increased when Amitriptyline is combined with Tucidinostat.
Methadone The risk or severity of QTc prolongation can be increased when Methadone is combined with Tucidinostat.
Diltiazem The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Tucidinostat.
Clozapine The risk or severity of QTc prolongation can be increased when Tucidinostat is combined with Clozapine.
Sulpiride The risk or severity of QTc prolongation can be increased when Sulpiride is combined with Tucidinostat.
Nimodipine The risk or severity of QTc prolongation can be increased when Nimodipine is combined with Tucidinostat.
Promazine The risk or severity of QTc prolongation can be increased when Promazine is combined with Tucidinostat.
Prochlorperazine The risk or severity of QTc prolongation can be increased when Prochlorperazine is combined with Tucidinostat.
Droperidol The risk or severity of QTc prolongation can be increased when Droperidol is combined with Tucidinostat.
Imipramine The risk or severity of QTc prolongation can be increased when Imipramine is combined with Tucidinostat.
Chlorpromazine The risk or severity of QTc prolongation can be increased when Chlorpromazine is combined with Tucidinostat.
Oxaliplatin The risk or severity of QTc prolongation can be increased when Oxaliplatin is combined with Tucidinostat.
Ciprofloxacin The risk or severity of QTc prolongation can be increased when Ciprofloxacin is combined with Tucidinostat.
Fluorouracil The risk or severity of QTc prolongation can be increased when Fluorouracil is combined with Tucidinostat.
Perflutren The risk or severity of QTc prolongation can be increased when Perflutren is combined with Tucidinostat.
Cinnarizine The risk or severity of QTc prolongation can be increased when Cinnarizine is combined with Tucidinostat.
Atropine The risk or severity of QTc prolongation can be increased when Atropine is combined with Tucidinostat.
Chloroquine The risk or severity of QTc prolongation can be increased when Chloroquine is combined with Tucidinostat.
Efavirenz The risk or severity of QTc prolongation can be increased when Efavirenz is combined with Tucidinostat.
Adenosine The risk or severity of QTc prolongation can be increased when Adenosine is combined with Tucidinostat.
Pentamidine The risk or severity of QTc prolongation can be increased when Pentamidine is combined with Tucidinostat.
Gadobenic acid The risk or severity of QTc prolongation can be increased when Gadobenic acid is combined with Tucidinostat.
Carbinoxamine The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Tucidinostat.
Dolasetron The risk or severity of QTc prolongation can be increased when Dolasetron is combined with Tucidinostat.
Roxithromycin The risk or severity of QTc prolongation can be increased when Roxithromycin is combined with Tucidinostat.
Nalidixic acid The risk or severity of QTc prolongation can be increased when Nalidixic acid is combined with Tucidinostat.
Cinoxacin The risk or severity of QTc prolongation can be increased when Cinoxacin is combined with Tucidinostat.
Loperamide The risk or severity of QTc prolongation can be increased when Loperamide is combined with Tucidinostat.
Granisetron The risk or severity of QTc prolongation can be increased when Granisetron is combined with Tucidinostat.
Ondansetron The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Tucidinostat.
Levosimendan The risk or severity of QTc prolongation can be increased when Levosimendan is combined with Tucidinostat.
Mesoridazine The risk or severity of QTc prolongation can be increased when Mesoridazine is combined with Tucidinostat.
Desloratadine The risk or severity of QTc prolongation can be increased when Desloratadine is combined with Tucidinostat.
Telithromycin The risk or severity of QTc prolongation can be increased when Telithromycin is combined with Tucidinostat.
Lomefloxacin The risk or severity of QTc prolongation can be increased when Lomefloxacin is combined with Tucidinostat.
Dimenhydrinate The risk or severity of QTc prolongation can be increased when Dimenhydrinate is combined with Tucidinostat.
Primaquine The risk or severity of QTc prolongation can be increased when Primaquine is combined with Tucidinostat.
Papaverine The risk or severity of QTc prolongation can be increased when Papaverine is combined with Tucidinostat.
Chlorpheniramine The risk or severity of QTc prolongation can be increased when Chlorpheniramine is combined with Tucidinostat.
Nifedipine The risk or severity of QTc prolongation can be increased when Nifedipine is combined with Tucidinostat.
Levofloxacin The risk or severity of QTc prolongation can be increased when Levofloxacin is combined with Tucidinostat.

Target Protein

Histone deacetylase 1 HDAC1

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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