Lanoteplase

DB06245

biotech investigational

Deskripsi

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

75 Data
Alteplase The risk or severity of angioedema can be increased when Alteplase is combined with Lanoteplase.
Urokinase The risk or severity of angioedema can be increased when Urokinase is combined with Lanoteplase.
Reteplase The risk or severity of angioedema can be increased when Reteplase is combined with Lanoteplase.
Anistreplase The risk or severity of angioedema can be increased when Anistreplase is combined with Lanoteplase.
Tenecteplase The risk or severity of angioedema can be increased when Tenecteplase is combined with Lanoteplase.
Streptokinase The risk or severity of angioedema can be increased when Streptokinase is combined with Lanoteplase.
Valsartan The risk or severity of angioedema can be increased when Valsartan is combined with Lanoteplase.
Ramipril The risk or severity of angioedema can be increased when Ramipril is combined with Lanoteplase.
Pregabalin The risk or severity of angioedema can be increased when Pregabalin is combined with Lanoteplase.
Conjugated estrogens The risk or severity of angioedema can be increased when Conjugated estrogens is combined with Lanoteplase.
Fosinopril The risk or severity of angioedema can be increased when Fosinopril is combined with Lanoteplase.
Trandolapril The risk or severity of angioedema can be increased when Trandolapril is combined with Lanoteplase.
Benazepril The risk or severity of angioedema can be increased when Benazepril is combined with Lanoteplase.
Enalapril The risk or severity of angioedema can be increased when Enalapril is combined with Lanoteplase.
Diclofenac The risk or severity of angioedema can be increased when Diclofenac is combined with Lanoteplase.
Losartan The risk or severity of angioedema can be increased when Losartan is combined with Lanoteplase.
Moexipril The risk or severity of angioedema can be increased when Moexipril is combined with Lanoteplase.
Lisinopril The risk or severity of angioedema can be increased when Lisinopril is combined with Lanoteplase.
Perindopril The risk or severity of angioedema can be increased when Perindopril is combined with Lanoteplase.
Eprosartan The risk or severity of angioedema can be increased when Eprosartan is combined with Lanoteplase.
Sirolimus The risk or severity of angioedema can be increased when Sirolimus is combined with Lanoteplase.
Quinapril The risk or severity of angioedema can be increased when Quinapril is combined with Lanoteplase.
Omapatrilat The risk or severity of angioedema can be increased when Omapatrilat is combined with Lanoteplase.
Acetylsalicylic acid The risk or severity of angioedema can be increased when Acetylsalicylic acid is combined with Lanoteplase.
Telmisartan The risk or severity of angioedema can be increased when Telmisartan is combined with Lanoteplase.
Ibuprofen The risk or severity of angioedema can be increased when Ibuprofen is combined with Lanoteplase.
Rescinnamine The risk or severity of angioedema can be increased when Rescinnamine is combined with Lanoteplase.
Captopril The risk or severity of angioedema can be increased when Captopril is combined with Lanoteplase.
Sitagliptin The risk or severity of angioedema can be increased when Sitagliptin is combined with Lanoteplase.
Cilazapril The risk or severity of angioedema can be increased when Cilazapril is combined with Lanoteplase.
Forasartan The risk or severity of angioedema can be increased when Forasartan is combined with Lanoteplase.
Saprisartan The risk or severity of angioedema can be increased when Saprisartan is combined with Lanoteplase.
Spirapril The risk or severity of angioedema can be increased when Spirapril is combined with Lanoteplase.
Vildagliptin The risk or severity of angioedema can be increased when Vildagliptin is combined with Lanoteplase.
AMG-222 The risk or severity of angioedema can be increased when AMG-222 is combined with Lanoteplase.
Bisegliptin The risk or severity of angioedema can be increased when Bisegliptin is combined with Lanoteplase.
Icatibant The risk or severity of angioedema can be increased when Icatibant is combined with Lanoteplase.
Alogliptin The risk or severity of angioedema can be increased when Alogliptin is combined with Lanoteplase.
Temsirolimus The risk or severity of angioedema can be increased when Lanoteplase is combined with Temsirolimus.
Saxagliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Saxagliptin.
Amediplase The risk or severity of angioedema can be increased when Lanoteplase is combined with Amediplase.
Gosogliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Gosogliptin.
Azilsartan medoxomil The risk or severity of angioedema can be increased when Lanoteplase is combined with Azilsartan medoxomil.
Temocapril The risk or severity of angioedema can be increased when Lanoteplase is combined with Temocapril.
Linagliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Linagliptin.
Sacubitril The risk or severity of angioedema can be increased when Lanoteplase is combined with Sacubitril.
Enalaprilat The risk or severity of angioedema can be increased when Lanoteplase is combined with Enalaprilat.
Dutogliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Dutogliptin.
Imidapril The risk or severity of angioedema can be increased when Lanoteplase is combined with Imidapril.
Teneligliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Teneligliptin.
Omarigliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Omarigliptin.
Carmegliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Carmegliptin.
Gemigliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Gemigliptin.
Anagliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Anagliptin.
Evogliptin The risk or severity of angioedema can be increased when Lanoteplase is combined with Evogliptin.
Zofenopril The risk or severity of angioedema can be increased when Lanoteplase is combined with Zofenopril.
Delapril The risk or severity of angioedema can be increased when Lanoteplase is combined with Delapril.
Saruplase The risk or severity of angioedema can be increased when Lanoteplase is combined with Saruplase.
Benazeprilat The risk or severity of angioedema can be increased when Lanoteplase is combined with Benazeprilat.
Fosinoprilat The risk or severity of angioedema can be increased when Lanoteplase is combined with Fosinoprilat.
Ramiprilat The risk or severity of angioedema can be increased when Lanoteplase is combined with Ramiprilat.
Trandolaprilat The risk or severity of angioedema can be increased when Lanoteplase is combined with Trandolaprilat.
Moexiprilat The risk or severity of angioedema can be increased when Lanoteplase is combined with Moexiprilat.
Perindoprilat The risk or severity of angioedema can be increased when Lanoteplase is combined with Perindoprilat.
Quinaprilat The risk or severity of angioedema can be increased when Lanoteplase is combined with Quinaprilat.
Quinoline Yellow WS The risk or severity of angioedema can be increased when Lanoteplase is combined with Quinoline Yellow WS.
Alpha-1-proteinase inhibitor The therapeutic efficacy of Alpha-1-proteinase inhibitor can be decreased when used in combination with Lanoteplase.
Menadione The therapeutic efficacy of Menadione can be decreased when used in combination with Lanoteplase.
Tranexamic acid The therapeutic efficacy of Tranexamic acid can be decreased when used in combination with Lanoteplase.
Aminocaproic acid The therapeutic efficacy of Aminocaproic acid can be decreased when used in combination with Lanoteplase.
Aprotinin The therapeutic efficacy of Aprotinin can be decreased when used in combination with Lanoteplase.
Hydrogen peroxide The therapeutic efficacy of Hydrogen peroxide can be decreased when used in combination with Lanoteplase.
Aminomethylbenzoic acid The therapeutic efficacy of Aminomethylbenzoic acid can be decreased when used in combination with Lanoteplase.
Camostat The therapeutic efficacy of Camostat can be decreased when used in combination with Lanoteplase.
Menadione bisulfite The therapeutic efficacy of Menadione bisulfite can be decreased when used in combination with Lanoteplase.

Target Protein

Urokinase plasminogen activator surface receptor PLAUR
Fibrinogen alpha chain FGA
Kallikrein-1 KLK1
Laminin subunit alpha-5 LAMA5
Coagulation factor X F10
Fibronectin FN1
Plasminogen activator inhibitor 2 SERPINB2
Tetranectin CLEC3B
Keratin, type II cytoskeletal 8 KRT8
Annexin A2 ANXA2
Laminin subunit beta-1 LAMB1
Laminin subunit gamma-1 LAMC1
Laminin subunit alpha-1 LAMA1
Calreticulin CALR
Calnexin CANX
Prolow-density lipoprotein receptor-related protein 1 LRP1
Laminin subunit alpha-3 LAMA3

Referensi & Sumber

Artikel (PubMed)
  • PMID: 18034528
    Zeymer U, Neuhaus KL: Lanoteplase: a viewpoint by Uwe Zeymer and Karl-Ludwig Neuhaus. BioDrugs. 2000 Mar;13(3):225-6.
  • PMID: 18034526
    Bhana N, Spencer CM: Lanoteplase. BioDrugs. 2000 Mar;13(3):217-24.
  • PMID: 10695501
    Nordt TK, Moser M, Kohler B, Kubler W, Bode C: Pharmacokinetics and pharmacodynamics of lanoteplase (n-PA). Thromb Haemost. 1999 Sep;82 Suppl 1:121-3.

Contoh Produk & Brand

Produk: 0 • International brands: 0
Belum ada data produk/brand untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field produk/brand.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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