Tedisamil

DB06200

small molecule investigational

Deskripsi

Tedisamil (planned trade name Pulzium) is an investigational drug for atrial fibrillation and atrial flutter. It is currently being developed by Solvay and is currently under regulatory review by the United States Food and Drug Administration.

Struktur Molekul 2D

Berat 288.4708
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

441 Data
Ivabradine Ivabradine may increase the QTc-prolonging activities of Tedisamil.
Fingolimod Fingolimod may increase the arrhythmogenic activities of Tedisamil.
Propafenone Propafenone may increase the arrhythmogenic activities of Tedisamil.
Metoprolol Metoprolol may increase the arrhythmogenic activities of Tedisamil.
Lidocaine Lidocaine may increase the arrhythmogenic activities of Tedisamil.
Atenolol Atenolol may increase the arrhythmogenic activities of Tedisamil.
Mexiletine Mexiletine may increase the arrhythmogenic activities of Tedisamil.
Nisoldipine Nisoldipine may increase the arrhythmogenic activities of Tedisamil.
Acetyldigitoxin Acetyldigitoxin may increase the arrhythmogenic activities of Tedisamil.
Lercanidipine Lercanidipine may increase the arrhythmogenic activities of Tedisamil.
Magnesium sulfate Magnesium sulfate may increase the arrhythmogenic activities of Tedisamil.
Alprenolol Alprenolol may increase the arrhythmogenic activities of Tedisamil.
Tocainide Tocainide may increase the arrhythmogenic activities of Tedisamil.
Deslanoside Deslanoside may increase the arrhythmogenic activities of Tedisamil.
Carvedilol Carvedilol may increase the arrhythmogenic activities of Tedisamil.
Nadolol Nadolol may increase the arrhythmogenic activities of Tedisamil.
Practolol Practolol may increase the arrhythmogenic activities of Tedisamil.
Aprindine Aprindine may increase the arrhythmogenic activities of Tedisamil.
Dexpropranolol Dexpropranolol may increase the arrhythmogenic activities of Tedisamil.
Nimesulide Nimesulide may increase the arrhythmogenic activities of Tedisamil.
Cyclandelate Cyclandelate may increase the arrhythmogenic activities of Tedisamil.
Flunarizine Flunarizine may increase the arrhythmogenic activities of Tedisamil.
Nebivolol Nebivolol may increase the arrhythmogenic activities of Tedisamil.
Clevidipine Clevidipine may increase the arrhythmogenic activities of Tedisamil.
Seletracetam Seletracetam may increase the arrhythmogenic activities of Tedisamil.
Nylidrin Nylidrin may increase the arrhythmogenic activities of Tedisamil.
Carteolol Tedisamil may increase the arrhythmogenic activities of Carteolol.
Metipranolol Tedisamil may increase the arrhythmogenic activities of Metipranolol.
Dotarizine Tedisamil may increase the arrhythmogenic activities of Dotarizine.
Xylometazoline Tedisamil may increase the arrhythmogenic activities of Xylometazoline.
Sparteine Tedisamil may increase the arrhythmogenic activities of Sparteine.
Tranilast Tedisamil may increase the arrhythmogenic activities of Tranilast.
Fasudil Tedisamil may increase the arrhythmogenic activities of Fasudil.
Agmatine Tedisamil may increase the arrhythmogenic activities of Agmatine.
Nicorandil Tedisamil may increase the arrhythmogenic activities of Nicorandil.
Barnidipine Tedisamil may increase the arrhythmogenic activities of Barnidipine.
Azelnidipine Tedisamil may increase the arrhythmogenic activities of Azelnidipine.
Cilnidipine Tedisamil may increase the arrhythmogenic activities of Cilnidipine.
Darodipine Tedisamil may increase the arrhythmogenic activities of Darodipine.
Manidipine Tedisamil may increase the arrhythmogenic activities of Manidipine.
Niludipine Tedisamil may increase the arrhythmogenic activities of Niludipine.
Tropisetron Tedisamil may increase the arrhythmogenic activities of Tropisetron.
Carboxyamidotriazole Tedisamil may increase the arrhythmogenic activities of Carboxyamidotriazole.
Naftopidil Tedisamil may increase the arrhythmogenic activities of Naftopidil.
Vinpocetine Tedisamil may increase the arrhythmogenic activities of Vinpocetine.
Landiolol Tedisamil may increase the arrhythmogenic activities of Landiolol.
Spiradoline Tedisamil may increase the arrhythmogenic activities of Spiradoline.
Cymarin Tedisamil may increase the arrhythmogenic activities of Cymarin.
Metildigoxin Tedisamil may increase the arrhythmogenic activities of Metildigoxin.
Tiracizine Tedisamil may increase the arrhythmogenic activities of Tiracizine.
Ethacizine Tedisamil may increase the arrhythmogenic activities of Ethacizine.
Hydroquinine Tedisamil may increase the arrhythmogenic activities of Hydroquinine.
Bioallethrin Tedisamil may increase the arrhythmogenic activities of Bioallethrin.
Tertatolol Tedisamil may increase the arrhythmogenic activities of Tertatolol.
Caroverine Tedisamil may increase the arrhythmogenic activities of Caroverine.
Fosfructose Tedisamil may increase the arrhythmogenic activities of Fosfructose.
WIN 55212-2 Tedisamil may increase the arrhythmogenic activities of WIN 55212-2.
Fish oil Tedisamil may increase the arrhythmogenic activities of Fish oil.
Emopamil Tedisamil may increase the arrhythmogenic activities of Emopamil.
Lomerizine Tedisamil may increase the arrhythmogenic activities of Lomerizine.
Tetrandrine Tedisamil may increase the arrhythmogenic activities of Tetrandrine.
Dexniguldipine Tedisamil may increase the arrhythmogenic activities of Dexniguldipine.
Fosinoprilat Tedisamil may increase the arrhythmogenic activities of Fosinoprilat.
Hydroquinidine Tedisamil may increase the arrhythmogenic activities of Hydroquinidine.
SOR-C13 Tedisamil may increase the arrhythmogenic activities of SOR-C13.
Dofetilide Dofetilide may increase the arrhythmogenic activities of Tedisamil.
Disopyramide Disopyramide may increase the arrhythmogenic activities of Tedisamil.
Ibutilide Ibutilide may increase the arrhythmogenic activities of Tedisamil.
Sotalol Sotalol may increase the arrhythmogenic activities of Tedisamil.
Quinidine Quinidine may increase the arrhythmogenic activities of Tedisamil.
Procainamide Procainamide may increase the arrhythmogenic activities of Tedisamil.
Bepridil Bepridil may increase the arrhythmogenic activities of Tedisamil.
Terodiline Tedisamil may increase the arrhythmogenic activities of Terodiline.
Betaxolol Betaxolol may increase the arrhythmogenic activities of Tedisamil.
Diltiazem Diltiazem may increase the arrhythmogenic activities of Tedisamil.
Nimodipine Nimodipine may increase the arrhythmogenic activities of Tedisamil.
Cinnarizine Cinnarizine may increase the arrhythmogenic activities of Tedisamil.
Propranolol Propranolol may increase the arrhythmogenic activities of Tedisamil.
Atropine Atropine may increase the arrhythmogenic activities of Tedisamil.
Adenosine Adenosine may increase the arrhythmogenic activities of Tedisamil.
Loperamide Loperamide may increase the arrhythmogenic activities of Tedisamil.
Levosimendan Levosimendan may increase the arrhythmogenic activities of Tedisamil.
Nifedipine Nifedipine may increase the arrhythmogenic activities of Tedisamil.
Acebutolol Acebutolol may increase the arrhythmogenic activities of Tedisamil.
Flecainide Flecainide may increase the arrhythmogenic activities of Tedisamil.
Mibefradil Mibefradil may increase the arrhythmogenic activities of Tedisamil.
Oxprenolol Oxprenolol may increase the arrhythmogenic activities of Tedisamil.
Prenylamine Prenylamine may increase the arrhythmogenic activities of Tedisamil.
Fluspirilene Fluspirilene may increase the arrhythmogenic activities of Tedisamil.
Azimilide Azimilide may increase the arrhythmogenic activities of Tedisamil.
Nilvadipine Tedisamil may increase the arrhythmogenic activities of Nilvadipine.
Fendiline Tedisamil may increase the arrhythmogenic activities of Fendiline.
Eperisone Tedisamil may increase the arrhythmogenic activities of Eperisone.
Melperone Tedisamil may increase the arrhythmogenic activities of Melperone.
Benidipine Tedisamil may increase the arrhythmogenic activities of Benidipine.
Simendan Tedisamil may increase the arrhythmogenic activities of Simendan.
Otilonium Tedisamil may increase the arrhythmogenic activities of Otilonium.
Nizofenone Tedisamil may increase the arrhythmogenic activities of Nizofenone.
Bunaftine Tedisamil may increase the arrhythmogenic activities of Bunaftine.
Lorcainide Tedisamil may increase the arrhythmogenic activities of Lorcainide.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 10707827
    Manoach M, Varon D, Tribulova N, Zinman T, Kaplan D, Khananshvili D, Shainberg A: The role of sarcoplasmic reticulum in the protective effect of class III drugs against Ca2+ overload. Gen Physiol Biophys. 1999 Dec;18 Suppl 1:19-25.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Pulzium

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