Atrasentan is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called endothelin-1 protein receptor antagonists. It is a novel, selective endothelin A receptor antagonist (SERA).
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Apalutamide | The serum concentration of Atrasentan can be decreased when it is combined with Apalutamide. |
| Cyclosporine | The excretion of Atrasentan can be decreased when combined with Cyclosporine. |
| Valsartan | The excretion of Atrasentan can be decreased when combined with Valsartan. |
| Troglitazone | The excretion of Atrasentan can be decreased when combined with Troglitazone. |
| Erythromycin | The excretion of Atrasentan can be decreased when combined with Erythromycin. |
| Sildenafil | The excretion of Atrasentan can be decreased when combined with Sildenafil. |
| Reserpine | The excretion of Atrasentan can be decreased when combined with Reserpine. |
| Pantoprazole | The excretion of Atrasentan can be decreased when combined with Pantoprazole. |
| Nelfinavir | The excretion of Atrasentan can be decreased when combined with Nelfinavir. |
| Indinavir | The excretion of Atrasentan can be decreased when combined with Indinavir. |
| Diethylstilbestrol | The excretion of Atrasentan can be decreased when combined with Diethylstilbestrol. |
| Conjugated estrogens | The excretion of Atrasentan can be decreased when combined with Conjugated estrogens. |
| Indomethacin | The excretion of Atrasentan can be decreased when combined with Indomethacin. |
| Digoxin | The excretion of Atrasentan can be decreased when combined with Digoxin. |
| Beclomethasone dipropionate | The excretion of Atrasentan can be decreased when combined with Beclomethasone dipropionate. |
| Progesterone | The excretion of Atrasentan can be decreased when combined with Progesterone. |
| Rosiglitazone | The excretion of Atrasentan can be decreased when combined with Rosiglitazone. |
| Cerivastatin | The excretion of Atrasentan can be decreased when combined with Cerivastatin. |
| Quinine | The excretion of Atrasentan can be decreased when combined with Quinine. |
| Ritonavir | The excretion of Atrasentan can be decreased when combined with Ritonavir. |
| Caspofungin | The excretion of Atrasentan can be decreased when combined with Caspofungin. |
| Vincristine | The excretion of Atrasentan can be decreased when combined with Vincristine. |
| Vinblastine | The excretion of Atrasentan can be decreased when combined with Vinblastine. |
| Levocarnitine | The excretion of Atrasentan can be decreased when combined with Levocarnitine. |
| Diclofenac | The excretion of Atrasentan can be decreased when combined with Diclofenac. |
| Fluticasone propionate | The excretion of Atrasentan can be decreased when combined with Fluticasone propionate. |
| Ivermectin | The excretion of Atrasentan can be decreased when combined with Ivermectin. |
| Nicardipine | The excretion of Atrasentan can be decreased when combined with Nicardipine. |
| Simvastatin | The excretion of Atrasentan can be decreased when combined with Simvastatin. |
| Nystatin | The excretion of Atrasentan can be decreased when combined with Nystatin. |
| Amprenavir | The excretion of Atrasentan can be decreased when combined with Amprenavir. |
| Irinotecan | The excretion of Atrasentan can be decreased when combined with Irinotecan. |
| Roxithromycin | The excretion of Atrasentan can be decreased when combined with Roxithromycin. |
| Estradiol | The excretion of Atrasentan can be decreased when combined with Estradiol. |
| Sulfasalazine | The excretion of Atrasentan can be decreased when combined with Sulfasalazine. |
| Mifepristone | The excretion of Atrasentan can be decreased when combined with Mifepristone. |
| Tacrolimus | The excretion of Atrasentan can be decreased when combined with Tacrolimus. |
| Sirolimus | The excretion of Atrasentan can be decreased when combined with Sirolimus. |
| Quinidine | The excretion of Atrasentan can be decreased when combined with Quinidine. |
| Tipranavir | The excretion of Atrasentan can be decreased when combined with Tipranavir. |
| Dipyridamole | The excretion of Atrasentan can be decreased when combined with Dipyridamole. |
| Telithromycin | The excretion of Atrasentan can be decreased when combined with Telithromycin. |
| Ketoconazole | The excretion of Atrasentan can be decreased when combined with Ketoconazole. |
| Novobiocin | The excretion of Atrasentan can be decreased when combined with Novobiocin. |
| Atazanavir | The excretion of Atrasentan can be decreased when combined with Atazanavir. |
| Atorvastatin | The excretion of Atrasentan can be decreased when combined with Atorvastatin. |
| Ouabain | The excretion of Atrasentan can be decreased when combined with Ouabain. |
| Fluvastatin | The excretion of Atrasentan can be decreased when combined with Fluvastatin. |
| Rosuvastatin | The excretion of Atrasentan can be decreased when combined with Rosuvastatin. |
| Saquinavir | The excretion of Atrasentan can be decreased when combined with Saquinavir. |
| Gemfibrozil | The excretion of Atrasentan can be decreased when combined with Gemfibrozil. |
| Darunavir | The excretion of Atrasentan can be decreased when combined with Darunavir. |
| Bezafibrate | The excretion of Atrasentan can be decreased when combined with Bezafibrate. |
| Everolimus | The excretion of Atrasentan can be decreased when combined with Everolimus. |
| Lopinavir | The excretion of Atrasentan can be decreased when combined with Lopinavir. |
| Genistein | The excretion of Atrasentan can be decreased when combined with Genistein. |
| Hyperforin | The excretion of Atrasentan can be decreased when combined with Hyperforin. |
| Cholic Acid | The excretion of Atrasentan can be increased when combined with Cholic Acid. |
| Fusidic acid | The excretion of Atrasentan can be decreased when combined with Fusidic acid. |
| Quercetin | The excretion of Atrasentan can be decreased when combined with Quercetin. |
| Taurocholic acid | The excretion of Atrasentan can be increased when combined with Taurocholic acid. |
| Posizolid | The excretion of Atrasentan can be decreased when combined with Posizolid. |
| Nilotinib | The excretion of Atrasentan can be decreased when combined with Nilotinib. |
| Telaprevir | The excretion of Atrasentan can be decreased when combined with Telaprevir. |
| Dovitinib | The excretion of Atrasentan can be decreased when combined with Dovitinib. |
| Acetylcysteine | The excretion of Atrasentan can be decreased when combined with Acetylcysteine. |
| Eltrombopag | The excretion of Atrasentan can be decreased when combined with Eltrombopag. |
| Simeprevir | The excretion of Atrasentan can be decreased when combined with Simeprevir. |
| Pazopanib | The excretion of Atrasentan can be decreased when combined with Pazopanib. |
| Axitinib | The excretion of Atrasentan can be decreased when combined with Axitinib. |
| Cholecystokinin | The excretion of Atrasentan can be decreased when combined with Cholecystokinin. |
| Rilpivirine | The excretion of Atrasentan can be decreased when combined with Rilpivirine. |
| Teriflunomide | The excretion of Atrasentan can be decreased when combined with Teriflunomide. |
| Dabrafenib | The excretion of Atrasentan can be decreased when combined with Dabrafenib. |
| Idelalisib | The excretion of Atrasentan can be decreased when combined with Idelalisib. |
| Cobicistat | The excretion of Atrasentan can be decreased when combined with Cobicistat. |
| Lenvatinib | The excretion of Atrasentan can be decreased when combined with Lenvatinib. |
| Daclatasvir | The excretion of Atrasentan can be decreased when combined with Daclatasvir. |
| Lobeglitazone | The excretion of Atrasentan can be decreased when combined with Lobeglitazone. |
| Eluxadoline | The excretion of Atrasentan can be decreased when combined with Eluxadoline. |
| Sacubitril | The excretion of Atrasentan can be decreased when combined with Sacubitril. |
| Paritaprevir | The excretion of Atrasentan can be decreased when combined with Paritaprevir. |
| Silibinin | The excretion of Atrasentan can be decreased when combined with Silibinin. |
| Venetoclax | The excretion of Atrasentan can be decreased when combined with Venetoclax. |
| Asunaprevir | The excretion of Atrasentan can be decreased when combined with Asunaprevir. |
| Velpatasvir | The excretion of Atrasentan can be decreased when combined with Velpatasvir. |
| Valspodar | The excretion of Atrasentan can be decreased when combined with Valspodar. |
| Voxilaprevir | The excretion of Atrasentan can be decreased when combined with Voxilaprevir. |
| Benzbromarone | The excretion of Atrasentan can be decreased when combined with Benzbromarone. |
| Fluticasone | The excretion of Atrasentan can be decreased when combined with Fluticasone. |
| Enasidenib | The excretion of Atrasentan can be decreased when combined with Enasidenib. |
| Pibrentasvir | The excretion of Atrasentan can be decreased when combined with Pibrentasvir. |
| Glecaprevir | The excretion of Atrasentan can be decreased when combined with Glecaprevir. |
| Candesartan | The excretion of Atrasentan can be decreased when combined with Candesartan. |
| Estradiol acetate | The excretion of Atrasentan can be decreased when combined with Estradiol acetate. |
| Estradiol benzoate | The excretion of Atrasentan can be decreased when combined with Estradiol benzoate. |
| Estradiol cypionate | The excretion of Atrasentan can be decreased when combined with Estradiol cypionate. |
| Estradiol dienanthate | The excretion of Atrasentan can be decreased when combined with Estradiol dienanthate. |
| Estradiol valerate | The excretion of Atrasentan can be decreased when combined with Estradiol valerate. |
| Pexidartinib | The excretion of Atrasentan can be decreased when combined with Pexidartinib. |