Zosuquidar

DB06191

small molecule investigational

Deskripsi

Zosuquidar is a compound of antineoplastic drug candidates currently under development. It is now in "Phase 3" of clinical tests in the United States. Its action mechanism consists of the inhibition of P-glycoproteins; other drugs with this mechanism include tariquidar and laniquidar.

Struktur Molekul 2D

Berat 527.616
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

160 Data
Afatinib The serum concentration of Afatinib can be increased when it is combined with Zosuquidar.
Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Zosuquidar.
Brentuximab vedotin The serum concentration of Brentuximab vedotin can be increased when it is combined with Zosuquidar.
Colchicine The serum concentration of Colchicine can be increased when it is combined with Zosuquidar.
Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Zosuquidar.
Ledipasvir The serum concentration of Ledipasvir can be increased when it is combined with Zosuquidar.
Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Zosuquidar.
Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Zosuquidar.
Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Zosuquidar.
Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Zosuquidar.
Silodosin The excretion of Silodosin can be decreased when combined with Zosuquidar.
Topotecan The serum concentration of Topotecan can be increased when it is combined with Zosuquidar.
Everolimus The serum concentration of Everolimus can be increased when it is combined with Zosuquidar.
Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Zosuquidar.
Vincristine The excretion of Vincristine can be decreased when combined with Zosuquidar.
Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Zosuquidar.
Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Zosuquidar.
Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Zosuquidar.
Sildenafil The serum concentration of Sildenafil can be increased when it is combined with Zosuquidar.
Morphine The serum concentration of Morphine can be increased when it is combined with Zosuquidar.
Tenofovir disoproxil The serum concentration of Tenofovir disoproxil can be increased when it is combined with Zosuquidar.
Clobazam The serum concentration of Clobazam can be increased when it is combined with Zosuquidar.
Quinine The serum concentration of Quinine can be increased when it is combined with Zosuquidar.
Toremifene The serum concentration of Toremifene can be increased when it is combined with Zosuquidar.
Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Zosuquidar.
Simvastatin The serum concentration of Simvastatin can be increased when it is combined with Zosuquidar.
Mannitol The serum concentration of Mannitol can be increased when it is combined with Zosuquidar.
Loperamide The excretion of Loperamide can be decreased when combined with Zosuquidar.
Vardenafil The serum concentration of Vardenafil can be increased when it is combined with Zosuquidar.
Clomifene The serum concentration of Clomifene can be increased when it is combined with Zosuquidar.
Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Zosuquidar.
Tegaserod The serum concentration of Tegaserod can be increased when it is combined with Zosuquidar.
Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Zosuquidar.
Sitagliptin The serum concentration of Sitagliptin can be increased when it is combined with Zosuquidar.
Posaconazole The serum concentration of Posaconazole can be increased when it is combined with Zosuquidar.
Paliperidone The serum concentration of Paliperidone can be increased when it is combined with Zosuquidar.
Belinostat The serum concentration of Belinostat can be increased when it is combined with Zosuquidar.
Indacaterol The serum concentration of Indacaterol can be increased when it is combined with Zosuquidar.
Telaprevir The serum concentration of Telaprevir can be increased when it is combined with Zosuquidar.
Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Zosuquidar.
Simeprevir The serum concentration of Simeprevir can be increased when it is combined with Zosuquidar.
Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Zosuquidar.
Apixaban The serum concentration of Apixaban can be increased when it is combined with Zosuquidar.
Odanacatib The serum concentration of Odanacatib can be increased when it is combined with Zosuquidar.
Ticagrelor The serum concentration of Ticagrelor can be increased when it is combined with Zosuquidar.
Linagliptin The serum concentration of Linagliptin can be increased when it is combined with Zosuquidar.
Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Zosuquidar.
Canagliflozin The serum concentration of Canagliflozin can be increased when it is combined with Zosuquidar.
Dolutegravir The serum concentration of Dolutegravir can be increased when it is combined with Zosuquidar.
Sofosbuvir The serum concentration of Sofosbuvir can be increased when it is combined with Zosuquidar.
Idelalisib The serum concentration of Idelalisib can be increased when it is combined with Zosuquidar.
Umeclidinium The serum concentration of Umeclidinium can be increased when it is combined with Zosuquidar.
Lenvatinib The serum concentration of Lenvatinib can be increased when it is combined with Zosuquidar.
Nintedanib The serum concentration of Nintedanib can be increased when it is combined with Zosuquidar.
Technetium Tc-99m sestamibi The serum concentration of Technetium Tc-99m sestamibi can be increased when it is combined with Zosuquidar.
Dasabuvir The serum concentration of Dasabuvir can be increased when it is combined with Zosuquidar.
Ombitasvir The serum concentration of Ombitasvir can be increased when it is combined with Zosuquidar.
Paritaprevir The serum concentration of Paritaprevir can be increased when it is combined with Zosuquidar.
Selexipag The serum concentration of Selexipag can be increased when it is combined with Zosuquidar.
Elbasvir The serum concentration of Elbasvir can be increased when it is combined with Zosuquidar.
Grazoprevir The serum concentration of Grazoprevir can be increased when it is combined with Zosuquidar.
Velpatasvir The serum concentration of Velpatasvir can be increased when it is combined with Zosuquidar.
Tezacaftor The serum concentration of Tezacaftor can be increased when it is combined with Zosuquidar.
Talinolol The serum concentration of Talinolol can be increased when it is combined with Zosuquidar.
Valspodar The serum concentration of Valspodar can be increased when it is combined with Zosuquidar.
Duvelisib The serum concentration of Duvelisib can be increased when it is combined with Zosuquidar.
Glasdegib The serum concentration of Glasdegib can be increased when it is combined with Zosuquidar.
Elagolix The serum concentration of Elagolix can be increased when it is combined with Zosuquidar.
Voxilaprevir The serum concentration of Voxilaprevir can be increased when it is combined with Zosuquidar.
Gilteritinib The serum concentration of Gilteritinib can be increased when it is combined with Zosuquidar.
Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Zosuquidar.
Grapiprant The serum concentration of Grapiprant can be increased when it is combined with Zosuquidar.
Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Zosuquidar.
Pibrentasvir The serum concentration of Pibrentasvir can be increased when it is combined with Zosuquidar.
Glecaprevir The serum concentration of Glecaprevir can be increased when it is combined with Zosuquidar.
Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Zosuquidar.
Fedratinib The serum concentration of Fedratinib can be increased when it is combined with Zosuquidar.
Lasmiditan The serum concentration of Lasmiditan can be increased when it is combined with Zosuquidar.
Enfortumab vedotin The serum concentration of Enfortumab vedotin can be increased when it is combined with Zosuquidar.
Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Zosuquidar.
Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Zosuquidar.
Tipranavir The serum concentration of Tipranavir can be increased when it is combined with Zosuquidar.
Mibefradil The serum concentration of Mibefradil can be increased when it is combined with Zosuquidar.
Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Zosuquidar.
Revefenacin The serum concentration of Revefenacin can be increased when it is combined with Zosuquidar.
Methylene blue The serum concentration of Methylene blue can be increased when it is combined with Zosuquidar.
Tucatinib The serum concentration of Tucatinib can be increased when it is combined with Zosuquidar.
Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Zosuquidar.
Ripretinib The serum concentration of Ripretinib can be increased when it is combined with Zosuquidar.
Fostemsavir The serum concentration of Fostemsavir can be increased when it is combined with Zosuquidar.
Prednisolone phosphate The serum concentration of Prednisolone phosphate can be increased when it is combined with Zosuquidar.
Belantamab mafodotin The serum concentration of Belantamab mafodotin can be increased when it is combined with Zosuquidar.
Mefloquine The serum concentration of Mefloquine can be increased when it is combined with Zosuquidar.
Cethromycin The serum concentration of Cethromycin can be increased when it is combined with Zosuquidar.
Darunavir The serum concentration of Darunavir can be increased when it is combined with Zosuquidar.
Voclosporin The serum concentration of Voclosporin can be increased when it is combined with Zosuquidar.
Trilaciclib The serum concentration of Trilaciclib can be increased when it is combined with Zosuquidar.
Daptomycin The serum concentration of Daptomycin can be increased when it is combined with Zosuquidar.
Avanafil The serum concentration of Avanafil can be increased when it is combined with Zosuquidar.
Tivozanib The serum concentration of Tivozanib can be increased when it is combined with Zosuquidar.

Target Protein

ATP-dependent translocase ABCB1 ABCB1
Phosphatidylcholine translocator ABCB4 ABCB4

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 0
Belum ada data produk/brand untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field produk/brand.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul