Garenoxacin

DB06160

small molecule investigational

Deskripsi

Garenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.

Struktur Molekul 2D

Berat 426.42
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

940 Data
Ivabradine Ivabradine may increase the QTc-prolonging activities of Garenoxacin.
Didanosine Didanosine can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Probenecid Probenecid may decrease the excretion rate of Garenoxacin which could result in a higher serum level.
Quinapril Quinapril can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium acetate Calcium acetate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron Dextran Iron Dextran can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium Calcium can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum carbonate Lanthanum carbonate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltose Ferric carboxymaltose can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron sucrose Iron sucrose can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric pyrophosphate Ferric pyrophosphate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium citrate Calcium citrate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium gluconate Calcium gluconate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric sulfate Ferric sulfate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cation Ferric cation can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Tetraferric tricitrate decahydrate Tetraferric tricitrate decahydrate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum III cation Lanthanum III cation can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium polycarbophil Calcium polycarbophil can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric oxyhydroxide Ferric oxyhydroxide can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sucralfate Sucralfate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Garenoxacin.
Nitrofurantoin The therapeutic efficacy of Garenoxacin can be decreased when used in combination with Nitrofurantoin.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Garenoxacin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Garenoxacin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Garenoxacin.
Insulin human The therapeutic efficacy of Insulin human can be increased when used in combination with Garenoxacin.
Insulin lispro The therapeutic efficacy of Insulin lispro can be increased when used in combination with Garenoxacin.
Insulin pork The therapeutic efficacy of Insulin pork can be increased when used in combination with Garenoxacin.
Troglitazone The therapeutic efficacy of Troglitazone can be increased when used in combination with Garenoxacin.
Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Garenoxacin.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Garenoxacin.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Garenoxacin.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Garenoxacin.
Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Garenoxacin.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Garenoxacin.
Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Garenoxacin.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Garenoxacin.
Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Garenoxacin.
Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Garenoxacin.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Garenoxacin.
Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Garenoxacin.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Garenoxacin.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Garenoxacin.
Sulfamethoxazole The therapeutic efficacy of Sulfamethoxazole can be increased when used in combination with Garenoxacin.
Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Garenoxacin.
Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Garenoxacin.
Gliclazide The therapeutic efficacy of Gliclazide can be increased when used in combination with Garenoxacin.
Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Garenoxacin.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Garenoxacin.
Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Garenoxacin.
Gliquidone The therapeutic efficacy of Gliquidone can be increased when used in combination with Garenoxacin.
Mitiglinide The therapeutic efficacy of Mitiglinide can be increased when used in combination with Garenoxacin.
Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Garenoxacin.
Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Garenoxacin.
Exenatide The therapeutic efficacy of Exenatide can be increased when used in combination with Garenoxacin.
Mecasermin The therapeutic efficacy of Mecasermin can be increased when used in combination with Garenoxacin.
Pramlintide The therapeutic efficacy of Pramlintide can be increased when used in combination with Garenoxacin.
Glisoxepide The therapeutic efficacy of Glisoxepide can be increased when used in combination with Garenoxacin.
Insulin aspart The therapeutic efficacy of Insulin aspart can be increased when used in combination with Garenoxacin.
Insulin glulisine The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Garenoxacin.
Glymidine The therapeutic efficacy of Glymidine can be increased when used in combination with Garenoxacin.
AICA ribonucleotide The therapeutic efficacy of AICA ribonucleotide can be increased when used in combination with Garenoxacin.
Buformin The therapeutic efficacy of Buformin can be increased when used in combination with Garenoxacin.
Vildagliptin The therapeutic efficacy of Vildagliptin can be increased when used in combination with Garenoxacin.
Voglibose The therapeutic efficacy of Voglibose can be increased when used in combination with Garenoxacin.
NN344 The therapeutic efficacy of NN344 can be increased when used in combination with Garenoxacin.
AMG-222 The therapeutic efficacy of AMG-222 can be increased when used in combination with Garenoxacin.
Bisegliptin The therapeutic efficacy of Bisegliptin can be increased when used in combination with Garenoxacin.
Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Garenoxacin.
Dapagliflozin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Garenoxacin.
Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Garenoxacin.
Liraglutide The therapeutic efficacy of Liraglutide can be increased when used in combination with Garenoxacin.
Gosogliptin The therapeutic efficacy of Gosogliptin can be increased when used in combination with Garenoxacin.
Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Garenoxacin.
Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Garenoxacin.
Glibornuride The therapeutic efficacy of Glibornuride can be increased when used in combination with Garenoxacin.
Benfluorex The therapeutic efficacy of Benfluorex can be increased when used in combination with Garenoxacin.
Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Garenoxacin.
Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Garenoxacin.
Dulaglutide The therapeutic efficacy of Dulaglutide can be increased when used in combination with Garenoxacin.
Lobeglitazone The therapeutic efficacy of Lobeglitazone can be increased when used in combination with Garenoxacin.
Netoglitazone The therapeutic efficacy of Netoglitazone can be increased when used in combination with Garenoxacin.
Rivoglitazone The therapeutic efficacy of Rivoglitazone can be increased when used in combination with Garenoxacin.
Ciglitazone The therapeutic efficacy of Ciglitazone can be increased when used in combination with Garenoxacin.
Lixisenatide The therapeutic efficacy of Lixisenatide can be increased when used in combination with Garenoxacin.
Insulin beef The therapeutic efficacy of Insulin beef can be increased when used in combination with Garenoxacin.
Insulin degludec The therapeutic efficacy of Insulin degludec can be increased when used in combination with Garenoxacin.
Insulin peglispro The therapeutic efficacy of Insulin peglispro can be increased when used in combination with Garenoxacin.
Insulin tregopil The therapeutic efficacy of Insulin tregopil can be increased when used in combination with Garenoxacin.
Ipragliflozin The therapeutic efficacy of Ipragliflozin can be increased when used in combination with Garenoxacin.
Dutogliptin The therapeutic efficacy of Dutogliptin can be increased when used in combination with Garenoxacin.
Allicin The therapeutic efficacy of Allicin can be increased when used in combination with Garenoxacin.
Tofogliflozin The therapeutic efficacy of Tofogliflozin can be increased when used in combination with Garenoxacin.
Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Garenoxacin.
2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Garenoxacin.
Teneligliptin The therapeutic efficacy of Teneligliptin can be increased when used in combination with Garenoxacin.
Omarigliptin The therapeutic efficacy of Omarigliptin can be increased when used in combination with Garenoxacin.
Carmegliptin The therapeutic efficacy of Carmegliptin can be increased when used in combination with Garenoxacin.

Target Protein

DNA topoisomerase 2-alpha TOP2A
DNA topoisomerase 2-beta TOP2B

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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