Eldelumab

DB06116

biotech investigational

Deskripsi

MDX-1100, a fully human antibody that targets IP10 (also known as CXCL10), a chemokine expressed in association with multiple inflammatory disease indications, such as rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

373 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Eldelumab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Eldelumab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Eldelumab.
Estrone Estrone may increase the thrombogenic activities of Eldelumab.
Estradiol Estradiol may increase the thrombogenic activities of Eldelumab.
Dienestrol Dienestrol may increase the thrombogenic activities of Eldelumab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Eldelumab.
Mestranol Mestranol may increase the thrombogenic activities of Eldelumab.
Estriol Estriol may increase the thrombogenic activities of Eldelumab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Eldelumab.
Quinestrol Quinestrol may increase the thrombogenic activities of Eldelumab.
Hexestrol Hexestrol may increase the thrombogenic activities of Eldelumab.
Tibolone Tibolone may increase the thrombogenic activities of Eldelumab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Eldelumab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Eldelumab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Eldelumab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Eldelumab.
Zeranol Zeranol may increase the thrombogenic activities of Eldelumab.
Equol Equol may increase the thrombogenic activities of Eldelumab.
Promestriene Promestriene may increase the thrombogenic activities of Eldelumab.
Methallenestril Methallenestril may increase the thrombogenic activities of Eldelumab.
Epimestrol Epimestrol may increase the thrombogenic activities of Eldelumab.
Moxestrol Moxestrol may increase the thrombogenic activities of Eldelumab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Eldelumab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Eldelumab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Eldelumab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Eldelumab.
Biochanin A Biochanin A may increase the thrombogenic activities of Eldelumab.
Formononetin Formononetin may increase the thrombogenic activities of Eldelumab.
Estetrol Estetrol may increase the thrombogenic activities of Eldelumab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Eldelumab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Eldelumab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Eldelumab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Eldelumab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Eldelumab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Eldelumab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Eldelumab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Eldelumab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Eldelumab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Eldelumab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Eldelumab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Eldelumab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Eldelumab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Eldelumab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Eldelumab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Eldelumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Eldelumab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Eldelumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Eldelumab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Eldelumab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Eldelumab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Eldelumab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Eldelumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Eldelumab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Eldelumab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Eldelumab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Eldelumab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Eldelumab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Eldelumab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Eldelumab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Eldelumab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Eldelumab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Eldelumab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Eldelumab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Eldelumab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Eldelumab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Eldelumab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Eldelumab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Eldelumab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Eldelumab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Eldelumab.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Eldelumab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Eldelumab.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Eldelumab.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Eldelumab.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Eldelumab.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Eldelumab.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Eldelumab.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Eldelumab.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with Eldelumab.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with Eldelumab.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Eldelumab.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with Eldelumab.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with Eldelumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Eldelumab.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with Eldelumab.
TNX-901 The risk or severity of adverse effects can be increased when TNX-901 is combined with Eldelumab.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Eldelumab.
RI 624 The risk or severity of adverse effects can be increased when RI 624 is combined with Eldelumab.
Stamulumab The risk or severity of adverse effects can be increased when MYO-029 is combined with Eldelumab.
CT-011 The risk or severity of adverse effects can be increased when CT-011 is combined with Eldelumab.
Leronlimab The risk or severity of adverse effects can be increased when Leronlimab is combined with Eldelumab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Eldelumab.
Olaratumab The risk or severity of adverse effects can be increased when Olaratumab is combined with Eldelumab.
IPH 2101 The risk or severity of adverse effects can be increased when IPH 2101 is combined with Eldelumab.
TB-402 The risk or severity of adverse effects can be increased when TB-402 is combined with Eldelumab.
Caplacizumab The risk or severity of adverse effects can be increased when Caplacizumab is combined with Eldelumab.
IMC-1C11 The risk or severity of adverse effects can be increased when IMC-1C11 is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when Eldelumab is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when Eldelumab is combined with Canakinumab.

Target Protein

C-X-C motif chemokine 10 CXCL10

Referensi & Sumber

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