Aldoxorubicin

DB06013

small molecule investigational

Deskripsi

Aldoxorubicin, an antineoplastic agents, is an albumin-binding prodrug of doxorubicin.

Struktur Molekul 2D

Berat 750.758
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

95 Data
Digoxin Digoxin may decrease the cardiotoxic activities of Aldoxorubicin.
Acetyldigitoxin Acetyldigitoxin may decrease the cardiotoxic activities of Aldoxorubicin.
Deslanoside Deslanoside may decrease the cardiotoxic activities of Aldoxorubicin.
Ouabain Ouabain may decrease the cardiotoxic activities of Aldoxorubicin.
Digitoxin Digitoxin may decrease the cardiotoxic activities of Aldoxorubicin.
Oleandrin Oleandrin may decrease the cardiotoxic activities of Aldoxorubicin.
Cymarin Cymarin may decrease the cardiotoxic activities of Aldoxorubicin.
Proscillaridin Proscillaridin may decrease the cardiotoxic activities of Aldoxorubicin.
Metildigoxin Metildigoxin may decrease the cardiotoxic activities of Aldoxorubicin.
Lanatoside C Lanatoside C may decrease the cardiotoxic activities of Aldoxorubicin.
Gitoformate Gitoformate may decrease the cardiotoxic activities of Aldoxorubicin.
Acetyldigoxin Acetyldigoxin may decrease the cardiotoxic activities of Aldoxorubicin.
Peruvoside Peruvoside may decrease the cardiotoxic activities of Aldoxorubicin.
Peginterferon alfa-2a The risk or severity of cardiotoxicity can be increased when Peginterferon alfa-2a is combined with Aldoxorubicin.
Bevacizumab The risk or severity of cardiotoxicity can be increased when Bevacizumab is combined with Aldoxorubicin.
Bortezomib The risk or severity of cardiotoxicity can be increased when Bortezomib is combined with Aldoxorubicin.
Cladribine The risk or severity of cardiotoxicity can be increased when Cladribine is combined with Aldoxorubicin.
Carmustine The risk or severity of cardiotoxicity can be increased when Carmustine is combined with Aldoxorubicin.
Amsacrine The risk or severity of cardiotoxicity can be increased when Amsacrine is combined with Aldoxorubicin.
Bleomycin The risk or severity of cardiotoxicity can be increased when Bleomycin is combined with Aldoxorubicin.
Mitomycin The risk or severity of cardiotoxicity can be increased when Mitomycin is combined with Aldoxorubicin.
Vindesine The risk or severity of cardiotoxicity can be increased when Vindesine is combined with Aldoxorubicin.
Vinorelbine The risk or severity of cardiotoxicity can be increased when Vinorelbine is combined with Aldoxorubicin.
Teniposide The risk or severity of cardiotoxicity can be increased when Teniposide is combined with Aldoxorubicin.
Epirubicin The risk or severity of cardiotoxicity can be increased when Epirubicin is combined with Aldoxorubicin.
Cisplatin The risk or severity of cardiotoxicity can be increased when Cisplatin is combined with Aldoxorubicin.
Cyclophosphamide The risk or severity of cardiotoxicity can be increased when Cyclophosphamide is combined with Aldoxorubicin.
Vincristine The risk or severity of cardiotoxicity can be increased when Vincristine is combined with Aldoxorubicin.
Fluorouracil The risk or severity of cardiotoxicity can be increased when Fluorouracil is combined with Aldoxorubicin.
Pentostatin The risk or severity of cardiotoxicity can be increased when Pentostatin is combined with Aldoxorubicin.
Methotrexate The risk or severity of cardiotoxicity can be increased when Methotrexate is combined with Aldoxorubicin.
Vinblastine The risk or severity of cardiotoxicity can be increased when Vinblastine is combined with Aldoxorubicin.
Imatinib The risk or severity of cardiotoxicity can be increased when Imatinib is combined with Aldoxorubicin.
Tamoxifen The risk or severity of cardiotoxicity can be increased when Tamoxifen is combined with Aldoxorubicin.
Daunorubicin The risk or severity of cardiotoxicity can be increased when Daunorubicin is combined with Aldoxorubicin.
Tretinoin The risk or severity of cardiotoxicity can be increased when Tretinoin is combined with Aldoxorubicin.
Etoposide The risk or severity of cardiotoxicity can be increased when Etoposide is combined with Aldoxorubicin.
Mechlorethamine The risk or severity of cardiotoxicity can be increased when Mechlorethamine is combined with Aldoxorubicin.
Doxorubicin The risk or severity of cardiotoxicity can be increased when Doxorubicin is combined with Aldoxorubicin.
Busulfan The risk or severity of cardiotoxicity can be increased when Busulfan is combined with Aldoxorubicin.
Thalidomide The risk or severity of cardiotoxicity can be increased when Thalidomide is combined with Aldoxorubicin.
Fludarabine The risk or severity of cardiotoxicity can be increased when Fludarabine is combined with Aldoxorubicin.
Capecitabine The risk or severity of cardiotoxicity can be increased when Capecitabine is combined with Aldoxorubicin.
Arsenic trioxide The risk or severity of cardiotoxicity can be increased when Arsenic trioxide is combined with Aldoxorubicin.
Idarubicin The risk or severity of cardiotoxicity can be increased when Idarubicin is combined with Aldoxorubicin.
Ifosfamide The risk or severity of cardiotoxicity can be increased when Ifosfamide is combined with Aldoxorubicin.
Mitoxantrone The risk or severity of cardiotoxicity can be increased when Mitoxantrone is combined with Aldoxorubicin.
Anastrozole The risk or severity of cardiotoxicity can be increased when Anastrozole is combined with Aldoxorubicin.
Paclitaxel The risk or severity of cardiotoxicity can be increased when Paclitaxel is combined with Aldoxorubicin.
Docetaxel The risk or severity of cardiotoxicity can be increased when Docetaxel is combined with Aldoxorubicin.
Paclitaxel trevatide The risk or severity of cardiotoxicity can be increased when Aldoxorubicin is combined with Paclitaxel trevatide.
Cabazitaxel The risk or severity of cardiotoxicity can be increased when Aldoxorubicin is combined with Cabazitaxel.
Paclitaxel poliglumex The risk or severity of cardiotoxicity can be increased when Aldoxorubicin is combined with Paclitaxel poliglumex.
Pertuzumab The risk or severity of cardiotoxicity can be increased when Aldoxorubicin is combined with Pertuzumab.
Trastuzumab The risk or severity of cardiotoxicity can be increased when Trastuzumab is combined with Aldoxorubicin.
Margetuximab The risk or severity of cardiotoxicity can be increased when Margetuximab is combined with Aldoxorubicin.
Darbepoetin alfa The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Aldoxorubicin.
Erythropoietin The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Aldoxorubicin.
Peginesatide The risk or severity of Thrombosis can be increased when Peginesatide is combined with Aldoxorubicin.
Methoxy polyethylene glycol-epoetin beta The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Aldoxorubicin.
Lidocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Lidocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Ropivacaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Bupivacaine.
Cinchocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Cinchocaine.
Dyclonine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Dyclonine.
Procaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Procaine.
Prilocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Prilocaine.
Proparacaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Proparacaine.
Meloxicam The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Meloxicam.
Oxybuprocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Oxybuprocaine.
Cocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Cocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Mepivacaine.
Levobupivacaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Levobupivacaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Diphenhydramine.
Benzocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Benzocaine.
Chloroprocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Chloroprocaine.
Phenol The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Phenol.
Tetrodotoxin The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Tetrodotoxin.
Benzyl alcohol The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Benzyl alcohol.
Capsaicin The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Capsaicin.
Etidocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Etidocaine.
Articaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Articaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Tetracaine.
Propoxycaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Propoxycaine.
Pramocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Pramocaine.
Butamben The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Butamben.
Butacaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Butacaine.
Oxetacaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Oxetacaine.
Ethyl chloride The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Ethyl chloride.
Butanilicaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Butanilicaine.
Metabutethamine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Metabutethamine.
Quinisocaine The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Quinisocaine.
Nelarabine The risk or severity of adverse effects can be increased when Nelarabine is combined with Aldoxorubicin.
Ambroxol The risk or severity of methemoglobinemia can be increased when Aldoxorubicin is combined with Ambroxol.
Etrasimod The risk or severity of immunosuppression can be increased when Aldoxorubicin is combined with Etrasimod.

Target Protein

DNA topoisomerase 2-alpha TOP2A
DNA topoisomerase 2-beta TOP2B

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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