Glembatumumab vedotin

DB05996

biotech investigational

Deskripsi

A conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin E for the treatment of melanoma and breast cancer.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

411 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Glembatumumab vedotin.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Glembatumumab vedotin.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Glembatumumab vedotin.
Estrone Estrone may increase the thrombogenic activities of Glembatumumab vedotin.
Estradiol Estradiol may increase the thrombogenic activities of Glembatumumab vedotin.
Dienestrol Dienestrol may increase the thrombogenic activities of Glembatumumab vedotin.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Glembatumumab vedotin.
Mestranol Mestranol may increase the thrombogenic activities of Glembatumumab vedotin.
Estriol Estriol may increase the thrombogenic activities of Glembatumumab vedotin.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Glembatumumab vedotin.
Quinestrol Quinestrol may increase the thrombogenic activities of Glembatumumab vedotin.
Hexestrol Hexestrol may increase the thrombogenic activities of Glembatumumab vedotin.
Tibolone Tibolone may increase the thrombogenic activities of Glembatumumab vedotin.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Glembatumumab vedotin.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Glembatumumab vedotin.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Glembatumumab vedotin.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Glembatumumab vedotin.
Zeranol Zeranol may increase the thrombogenic activities of Glembatumumab vedotin.
Equol Equol may increase the thrombogenic activities of Glembatumumab vedotin.
Promestriene Promestriene may increase the thrombogenic activities of Glembatumumab vedotin.
Methallenestril Methallenestril may increase the thrombogenic activities of Glembatumumab vedotin.
Epimestrol Epimestrol may increase the thrombogenic activities of Glembatumumab vedotin.
Moxestrol Moxestrol may increase the thrombogenic activities of Glembatumumab vedotin.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Glembatumumab vedotin.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Glembatumumab vedotin.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Glembatumumab vedotin.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Glembatumumab vedotin.
Biochanin A Biochanin A may increase the thrombogenic activities of Glembatumumab vedotin.
Formononetin Formononetin may increase the thrombogenic activities of Glembatumumab vedotin.
Estetrol Estetrol may increase the thrombogenic activities of Glembatumumab vedotin.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Glembatumumab vedotin.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Glembatumumab vedotin.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Glembatumumab vedotin.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Glembatumumab vedotin.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Glembatumumab vedotin.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Glembatumumab vedotin.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Glembatumumab vedotin.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Glembatumumab vedotin.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Glembatumumab vedotin.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Glembatumumab vedotin.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Glembatumumab vedotin.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Glembatumumab vedotin.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Glembatumumab vedotin.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Glembatumumab vedotin.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Glembatumumab vedotin.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Glembatumumab vedotin.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Glembatumumab vedotin.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Glembatumumab vedotin.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Glembatumumab vedotin.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Glembatumumab vedotin.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Glembatumumab vedotin.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Glembatumumab vedotin.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Glembatumumab vedotin.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Glembatumumab vedotin.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Glembatumumab vedotin.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Glembatumumab vedotin.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Glembatumumab vedotin.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Glembatumumab vedotin.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Glembatumumab vedotin.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Glembatumumab vedotin.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Glembatumumab vedotin.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Glembatumumab vedotin.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Glembatumumab vedotin.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Glembatumumab vedotin.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Glembatumumab vedotin.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Glembatumumab vedotin.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Glembatumumab vedotin.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Glembatumumab vedotin.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Glembatumumab vedotin.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Glembatumumab vedotin.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Glembatumumab vedotin.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Glembatumumab vedotin.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Glembatumumab vedotin.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Glembatumumab vedotin.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Glembatumumab vedotin.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Glembatumumab vedotin.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Glembatumumab vedotin.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Glembatumumab vedotin.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Glembatumumab vedotin.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with Glembatumumab vedotin.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with Glembatumumab vedotin.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Glembatumumab vedotin.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with Glembatumumab vedotin.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with Glembatumumab vedotin.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Glembatumumab vedotin.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with Glembatumumab vedotin.
TNX-901 The risk or severity of adverse effects can be increased when TNX-901 is combined with Glembatumumab vedotin.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Glembatumumab vedotin.
RI 624 The risk or severity of adverse effects can be increased when RI 624 is combined with Glembatumumab vedotin.
Stamulumab The risk or severity of adverse effects can be increased when MYO-029 is combined with Glembatumumab vedotin.
CT-011 The risk or severity of adverse effects can be increased when CT-011 is combined with Glembatumumab vedotin.
Leronlimab The risk or severity of adverse effects can be increased when Leronlimab is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Canakinumab.

Target Protein

Transmembrane glycoprotein NMB GPNMB

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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