CT-011

DB05916

biotech investigational

Deskripsi

CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

411 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of CT-011.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of CT-011.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of CT-011.
Estrone Estrone may increase the thrombogenic activities of CT-011.
Estradiol Estradiol may increase the thrombogenic activities of CT-011.
Dienestrol Dienestrol may increase the thrombogenic activities of CT-011.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of CT-011.
Mestranol Mestranol may increase the thrombogenic activities of CT-011.
Estriol Estriol may increase the thrombogenic activities of CT-011.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of CT-011.
Quinestrol Quinestrol may increase the thrombogenic activities of CT-011.
Hexestrol Hexestrol may increase the thrombogenic activities of CT-011.
Tibolone Tibolone may increase the thrombogenic activities of CT-011.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of CT-011.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of CT-011.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of CT-011.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of CT-011.
Zeranol Zeranol may increase the thrombogenic activities of CT-011.
Equol Equol may increase the thrombogenic activities of CT-011.
Promestriene Promestriene may increase the thrombogenic activities of CT-011.
Methallenestril Methallenestril may increase the thrombogenic activities of CT-011.
Epimestrol Epimestrol may increase the thrombogenic activities of CT-011.
Moxestrol Moxestrol may increase the thrombogenic activities of CT-011.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of CT-011.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of CT-011.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of CT-011.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of CT-011.
Biochanin A Biochanin A may increase the thrombogenic activities of CT-011.
Formononetin Formononetin may increase the thrombogenic activities of CT-011.
Estetrol Estetrol may increase the thrombogenic activities of CT-011.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with CT-011.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with CT-011.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with CT-011.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with CT-011.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with CT-011.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with CT-011.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with CT-011.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with CT-011.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with CT-011.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with CT-011.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with CT-011.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with CT-011.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with CT-011.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with CT-011.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with CT-011.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with CT-011.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with CT-011.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with CT-011.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with CT-011.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with CT-011.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with CT-011.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with CT-011.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with CT-011.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with CT-011.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with CT-011.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with CT-011.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with CT-011.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with CT-011.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with CT-011.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with CT-011.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with CT-011.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with CT-011.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with CT-011.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with CT-011.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with CT-011.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with CT-011.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with CT-011.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with CT-011.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with CT-011.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with CT-011.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with CT-011.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with CT-011.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with CT-011.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with CT-011.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with CT-011.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with CT-011.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with CT-011.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with CT-011.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with CT-011.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with CT-011.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with CT-011.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with CT-011.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with CT-011.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with CT-011.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with CT-011.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with CT-011.
TNX-901 The risk or severity of adverse effects can be increased when TNX-901 is combined with CT-011.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with CT-011.
RI 624 The risk or severity of adverse effects can be increased when RI 624 is combined with CT-011.
Stamulumab The risk or severity of adverse effects can be increased when MYO-029 is combined with CT-011.
Leronlimab The risk or severity of adverse effects can be increased when CT-011 is combined with Leronlimab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when CT-011 is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when CT-011 is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when CT-011 is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when CT-011 is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when CT-011 is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when CT-011 is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when CT-011 is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when CT-011 is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when CT-011 is combined with Canakinumab.

Target Protein

Programmed cell death protein 1 PDCD1

Referensi & Sumber

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