Prasterone sulfate

DB05804

small molecule investigational

Deskripsi

DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.

Struktur Molekul 2D

Berat 368.488
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

246 Data
Cyclosporine Cyclosporine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Troglitazone Troglitazone may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Reserpine Reserpine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Progesterone Progesterone may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Chlorpromazine Chlorpromazine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Celecoxib Celecoxib may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Cimetidine Cimetidine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Bosentan Bosentan may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Tipranavir Tipranavir may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Ethinylestradiol Ethinylestradiol may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Glyburide Glyburide may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Ursodeoxycholic acid Ursodeoxycholic acid may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Cholic Acid Cholic Acid may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Fusidic acid Fusidic acid may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Simeprevir Simeprevir may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Lenvatinib Lenvatinib may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Letermovir The metabolism of Prasterone sulfate can be decreased when combined with Letermovir.
Valinomycin Valinomycin may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Olmesartan Olmesartan may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Pralsetinib Pralsetinib may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Erythromycin Erythromycin may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Flunisolide The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Flunisolide.
Beclomethasone dipropionate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Beclomethasone dipropionate.
Betamethasone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Betamethasone.
Fluticasone propionate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluticasone propionate.
Fluocinolone acetonide The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluocinolone acetonide.
Triamcinolone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Triamcinolone.
Prednisone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Prednisone.
Fludrocortisone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fludrocortisone.
Hydrocortisone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Hydrocortisone.
Prednisolone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Prednisolone.
Methylprednisolone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Methylprednisolone.
Trilostane The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Trilostane.
Budesonide The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Budesonide.
Corticotropin The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Corticotropin.
Cortisone acetate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Cortisone acetate.
Paramethasone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Paramethasone.
Ciclesonide The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Ciclesonide.
Aldosterone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Aldosterone.
Fluticasone furoate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluticasone furoate.
Fluprednidene The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluprednidene.
Tixocortol The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Tixocortol.
Fluprednisolone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluprednisolone.
Meprednisone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Meprednisone.
Dexamethasone isonicotinate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Dexamethasone isonicotinate.
Melengestrol The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Melengestrol.
Deflazacort The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Deflazacort.
Cortivazol The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Cortivazol.
Prednylidene The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Prednylidene.
Fluocortin The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluocortin.
Fluperolone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluperolone.
Cloprednol The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Cloprednol.
Fluclorolone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluclorolone.
Fluticasone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluticasone.
Mometasone furoate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Mometasone furoate.
Hydrocortisone acetate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Hydrocortisone acetate.
Hydrocortisone cypionate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Hydrocortisone cypionate.
Hydrocortisone succinate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Hydrocortisone succinate.
Prednisolone phosphate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Prednisolone phosphate.
Prednisolone hemisuccinate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Prednisolone hemisuccinate.
Methylprednisolone hemisuccinate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Methylprednisolone hemisuccinate.
Prednisone acetate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Prednisone acetate.
Clocortolone acetate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Clocortolone acetate.
Melengestrol acetate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Melengestrol acetate.
Betamethasone phosphate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Betamethasone phosphate.
Cortisone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Cortisone.
Dexamethasone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Dexamethasone.
Clobetasol propionate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Clobetasol propionate.
Fluocinonide The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluocinonide.
Hydrocortisone butyrate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Hydrocortisone butyrate.
Desoximetasone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Desoximetasone.
Mometasone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Mometasone.
Fluocortolone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluocortolone.
Prednisolone acetate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Prednisolone acetate.
Fluorometholone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Fluorometholone.
Difluocortolone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Difluocortolone.
Flumethasone The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Flumethasone.
Methylprednisolone aceponate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Methylprednisolone aceponate.
Phenobarbital Phenobarbital may increase the excretion rate of Prasterone sulfate which could result in a lower serum level and potentially a reduction in efficacy.
Deoxycholic acid Deoxycholic acid may increase the excretion rate of Prasterone sulfate which could result in a lower serum level and potentially a reduction in efficacy.
Taurocholic acid Taurocholic acid may increase the excretion rate of Prasterone sulfate which could result in a lower serum level and potentially a reduction in efficacy.
Dexamethasone acetate The risk or severity of edema formation can be increased when Prasterone sulfate is combined with Dexamethasone acetate.
Pravastatin Pravastatin may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Glimepiride Glimepiride may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Indinavir Indinavir may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Lovastatin The metabolism of Prasterone sulfate can be decreased when combined with Lovastatin.
Ranolazine Ranolazine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Diethylstilbestrol Diethylstilbestrol may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Isradipine Isradipine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Flucloxacillin Flucloxacillin may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Indomethacin Indomethacin may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Atenolol Atenolol may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Terfenadine Terfenadine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Rosiglitazone Rosiglitazone may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Cerivastatin Cerivastatin may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Loratadine Loratadine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Atropine Atropine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Diclofenac Diclofenac may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Nicardipine Nicardipine may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.
Simvastatin Simvastatin may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.

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