TNX-901

DB05797

biotech investigational

Deskripsi

TNX-901 is a therapeutic monoclonal antibodies designed to address significant unmet medical needs in the areas of asthma, allergy, inflammation and other diseases affecting the human immune system.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

373 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of TNX-901.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of TNX-901.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of TNX-901.
Estrone Estrone may increase the thrombogenic activities of TNX-901.
Estradiol Estradiol may increase the thrombogenic activities of TNX-901.
Dienestrol Dienestrol may increase the thrombogenic activities of TNX-901.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of TNX-901.
Mestranol Mestranol may increase the thrombogenic activities of TNX-901.
Estriol Estriol may increase the thrombogenic activities of TNX-901.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of TNX-901.
Quinestrol Quinestrol may increase the thrombogenic activities of TNX-901.
Hexestrol Hexestrol may increase the thrombogenic activities of TNX-901.
Tibolone Tibolone may increase the thrombogenic activities of TNX-901.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of TNX-901.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of TNX-901.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of TNX-901.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of TNX-901.
Zeranol Zeranol may increase the thrombogenic activities of TNX-901.
Equol Equol may increase the thrombogenic activities of TNX-901.
Promestriene Promestriene may increase the thrombogenic activities of TNX-901.
Methallenestril Methallenestril may increase the thrombogenic activities of TNX-901.
Epimestrol Epimestrol may increase the thrombogenic activities of TNX-901.
Moxestrol Moxestrol may increase the thrombogenic activities of TNX-901.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of TNX-901.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of TNX-901.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of TNX-901.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of TNX-901.
Biochanin A Biochanin A may increase the thrombogenic activities of TNX-901.
Formononetin Formononetin may increase the thrombogenic activities of TNX-901.
Estetrol Estetrol may increase the thrombogenic activities of TNX-901.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with TNX-901.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with TNX-901.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with TNX-901.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with TNX-901.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with TNX-901.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with TNX-901.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with TNX-901.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with TNX-901.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with TNX-901.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with TNX-901.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with TNX-901.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with TNX-901.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with TNX-901.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with TNX-901.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with TNX-901.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with TNX-901.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with TNX-901.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with TNX-901.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with TNX-901.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with TNX-901.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with TNX-901.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with TNX-901.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with TNX-901.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with TNX-901.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with TNX-901.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with TNX-901.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with TNX-901.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with TNX-901.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with TNX-901.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with TNX-901.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with TNX-901.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with TNX-901.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with TNX-901.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with TNX-901.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with TNX-901.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with TNX-901.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with TNX-901.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with TNX-901.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with TNX-901.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with TNX-901.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with TNX-901.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with TNX-901.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with TNX-901.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with TNX-901.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with TNX-901.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with TNX-901.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with TNX-901.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with TNX-901.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with TNX-901.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with TNX-901.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with TNX-901.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with TNX-901.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with TNX-901.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with TNX-901.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with TNX-901.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with TNX-901.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when TNX-901 is combined with Inotuzumab ozogamicin.
RI 624 The risk or severity of adverse effects can be increased when TNX-901 is combined with RI 624.
Stamulumab The risk or severity of adverse effects can be increased when TNX-901 is combined with MYO-029.
CT-011 The risk or severity of adverse effects can be increased when TNX-901 is combined with CT-011.
Leronlimab The risk or severity of adverse effects can be increased when TNX-901 is combined with Leronlimab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when TNX-901 is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when TNX-901 is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when TNX-901 is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when TNX-901 is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when TNX-901 is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when TNX-901 is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when TNX-901 is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when TNX-901 is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when TNX-901 is combined with Canakinumab.

Target Protein

High affinity immunoglobulin epsilon receptor subunit alpha FCER1A

Referensi & Sumber

Artikel (PubMed)
  • PMID: 15025403
    Leung DY, Shanahan WR Jr, Li XM, Sampson HA: New approaches for the treatment of anaphylaxis. Novartis Found Symp. 2004;257:248-60; discussion 260-4, 276-85.

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