Farletuzumab

DB05595

biotech investigational

Deskripsi

Farletuzumab (MORAb-003) is a fully humanized monoclonal antibody against the folate receptor alpha, for the potential treatment of epithelial ovarian cancer.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

412 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Farletuzumab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Farletuzumab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Farletuzumab.
Estrone Estrone may increase the thrombogenic activities of Farletuzumab.
Estradiol Estradiol may increase the thrombogenic activities of Farletuzumab.
Dienestrol Dienestrol may increase the thrombogenic activities of Farletuzumab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Farletuzumab.
Mestranol Mestranol may increase the thrombogenic activities of Farletuzumab.
Estriol Estriol may increase the thrombogenic activities of Farletuzumab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Farletuzumab.
Quinestrol Quinestrol may increase the thrombogenic activities of Farletuzumab.
Hexestrol Hexestrol may increase the thrombogenic activities of Farletuzumab.
Tibolone Tibolone may increase the thrombogenic activities of Farletuzumab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Farletuzumab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Farletuzumab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Farletuzumab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Farletuzumab.
Zeranol Zeranol may increase the thrombogenic activities of Farletuzumab.
Equol Equol may increase the thrombogenic activities of Farletuzumab.
Promestriene Promestriene may increase the thrombogenic activities of Farletuzumab.
Methallenestril Methallenestril may increase the thrombogenic activities of Farletuzumab.
Epimestrol Epimestrol may increase the thrombogenic activities of Farletuzumab.
Moxestrol Moxestrol may increase the thrombogenic activities of Farletuzumab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Farletuzumab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Farletuzumab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Farletuzumab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Farletuzumab.
Biochanin A Biochanin A may increase the thrombogenic activities of Farletuzumab.
Formononetin Formononetin may increase the thrombogenic activities of Farletuzumab.
Estetrol Estetrol may increase the thrombogenic activities of Farletuzumab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Farletuzumab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Farletuzumab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Farletuzumab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Farletuzumab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Farletuzumab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Farletuzumab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Farletuzumab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Farletuzumab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Farletuzumab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Farletuzumab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Farletuzumab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Farletuzumab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Farletuzumab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Farletuzumab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Farletuzumab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Farletuzumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Farletuzumab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Farletuzumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Farletuzumab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Farletuzumab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Farletuzumab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Farletuzumab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Farletuzumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Farletuzumab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Farletuzumab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Farletuzumab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Farletuzumab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Farletuzumab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Farletuzumab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Farletuzumab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Farletuzumab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Farletuzumab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Farletuzumab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Farletuzumab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Farletuzumab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Farletuzumab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Farletuzumab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Farletuzumab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Farletuzumab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Farletuzumab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Farletuzumab.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Farletuzumab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Farletuzumab.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Farletuzumab.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Farletuzumab.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Farletuzumab.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Farletuzumab.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Farletuzumab.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Farletuzumab.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with Farletuzumab.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with Farletuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Veltuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Ustekinumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Farletuzumab is combined with Trastuzumab emtansine.
PRO-542 The risk or severity of adverse effects can be increased when Farletuzumab is combined with PRO-542.
TNX-901 The risk or severity of adverse effects can be increased when Farletuzumab is combined with TNX-901.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Farletuzumab is combined with Inotuzumab ozogamicin.
RI 624 The risk or severity of adverse effects can be increased when Farletuzumab is combined with RI 624.
Stamulumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with MYO-029.
CT-011 The risk or severity of adverse effects can be increased when Farletuzumab is combined with CT-011.
Leronlimab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Leronlimab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Farletuzumab is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when Farletuzumab is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when Farletuzumab is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when Farletuzumab is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Canakinumab.

Target Protein

Folate receptor alpha FOLR1

Referensi & Sumber

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