Iratumumab

DB05550

biotech investigational

Deskripsi

Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer. Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

372 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Iratumumab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Iratumumab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Iratumumab.
Estrone Estrone may increase the thrombogenic activities of Iratumumab.
Estradiol Estradiol may increase the thrombogenic activities of Iratumumab.
Dienestrol Dienestrol may increase the thrombogenic activities of Iratumumab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Iratumumab.
Mestranol Mestranol may increase the thrombogenic activities of Iratumumab.
Estriol Estriol may increase the thrombogenic activities of Iratumumab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Iratumumab.
Quinestrol Quinestrol may increase the thrombogenic activities of Iratumumab.
Hexestrol Hexestrol may increase the thrombogenic activities of Iratumumab.
Tibolone Tibolone may increase the thrombogenic activities of Iratumumab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Iratumumab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Iratumumab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Iratumumab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Iratumumab.
Zeranol Zeranol may increase the thrombogenic activities of Iratumumab.
Equol Equol may increase the thrombogenic activities of Iratumumab.
Promestriene Promestriene may increase the thrombogenic activities of Iratumumab.
Methallenestril Methallenestril may increase the thrombogenic activities of Iratumumab.
Epimestrol Epimestrol may increase the thrombogenic activities of Iratumumab.
Moxestrol Moxestrol may increase the thrombogenic activities of Iratumumab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Iratumumab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Iratumumab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Iratumumab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Iratumumab.
Biochanin A Biochanin A may increase the thrombogenic activities of Iratumumab.
Formononetin Formononetin may increase the thrombogenic activities of Iratumumab.
Estetrol Estetrol may increase the thrombogenic activities of Iratumumab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Iratumumab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Iratumumab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Iratumumab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Iratumumab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Iratumumab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Iratumumab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Iratumumab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Iratumumab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Iratumumab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Iratumumab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Iratumumab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Iratumumab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Iratumumab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Iratumumab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Iratumumab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Iratumumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Iratumumab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Iratumumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Iratumumab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Iratumumab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Iratumumab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Iratumumab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Iratumumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Iratumumab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Iratumumab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Iratumumab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Iratumumab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Iratumumab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Iratumumab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Iratumumab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Iratumumab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Iratumumab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Iratumumab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Iratumumab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Iratumumab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Iratumumab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Iratumumab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Iratumumab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Iratumumab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Iratumumab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Iratumumab.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Iratumumab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Iratumumab.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Iratumumab.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Iratumumab.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Iratumumab.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Iratumumab.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Iratumumab.
Enokizumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Enokizumab.
Ramucirumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Ramucirumab.
Farletuzumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Farletuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Veltuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Ustekinumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Iratumumab is combined with Trastuzumab emtansine.
PRO-542 The risk or severity of adverse effects can be increased when Iratumumab is combined with PRO-542.
TNX-901 The risk or severity of adverse effects can be increased when Iratumumab is combined with TNX-901.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Iratumumab is combined with Inotuzumab ozogamicin.
RI 624 The risk or severity of adverse effects can be increased when Iratumumab is combined with RI 624.
Stamulumab The risk or severity of adverse effects can be increased when Iratumumab is combined with MYO-029.
CT-011 The risk or severity of adverse effects can be increased when Iratumumab is combined with CT-011.
Leronlimab The risk or severity of adverse effects can be increased when Iratumumab is combined with Leronlimab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Iratumumab is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when Iratumumab is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when Iratumumab is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when Iratumumab is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when Iratumumab is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Canakinumab.

Target Protein

Tumor necrosis factor receptor superfamily member 8 TNFRSF8

Referensi & Sumber

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