Technetium Tc-99m ciprofloxacin

DB05488

small molecule investigational

Deskripsi

99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound infection, abdominal abscess, pneumonia, appendicitis and tuberculosis. INFECTON combines the widely used antibiotic, ciprofloxacin, with Technetium ((99m)Tc), the most commonly used radioisotope in nuclear medical imaging There is currently controversy around the drug's ability to discriminate between sterile inflammation and bacterial versus nonbacterial infections.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

936 Data
Ivabradine Ivabradine may increase the QTc-prolonging activities of Technetium Tc-99m ciprofloxacin.
Didanosine Didanosine can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Probenecid Probenecid may decrease the excretion rate of Technetium Tc-99m ciprofloxacin which could result in a higher serum level.
Quinapril Quinapril can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium acetate Calcium acetate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron Dextran Iron Dextran can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium Calcium can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum carbonate Lanthanum carbonate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltose Ferric carboxymaltose can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron sucrose Iron sucrose can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric pyrophosphate Ferric pyrophosphate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium citrate Calcium citrate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium gluconate Calcium gluconate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric sulfate Ferric sulfate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cation Ferric cation can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Tetraferric tricitrate decahydrate Tetraferric tricitrate decahydrate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum III cation Lanthanum III cation can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium polycarbophil Calcium polycarbophil can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric oxyhydroxide Ferric oxyhydroxide can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sucralfate Sucralfate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Technetium Tc-99m ciprofloxacin.
Nitrofurantoin The therapeutic efficacy of Technetium Tc-99m ciprofloxacin can be decreased when used in combination with Nitrofurantoin.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Technetium Tc-99m ciprofloxacin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Technetium Tc-99m ciprofloxacin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Technetium Tc-99m ciprofloxacin.
Insulin human The therapeutic efficacy of Insulin human can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Insulin lispro The therapeutic efficacy of Insulin lispro can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Insulin pork The therapeutic efficacy of Insulin pork can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Troglitazone The therapeutic efficacy of Troglitazone can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Sulfamethoxazole The therapeutic efficacy of Sulfamethoxazole can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Gliclazide The therapeutic efficacy of Gliclazide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Gliquidone The therapeutic efficacy of Gliquidone can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Mitiglinide The therapeutic efficacy of Mitiglinide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Exenatide The therapeutic efficacy of Exenatide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Mecasermin The therapeutic efficacy of Mecasermin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Pramlintide The therapeutic efficacy of Pramlintide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Glisoxepide The therapeutic efficacy of Glisoxepide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Insulin aspart The therapeutic efficacy of Insulin aspart can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Insulin glulisine The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Glymidine The therapeutic efficacy of Glymidine can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
AICA ribonucleotide The therapeutic efficacy of AICA ribonucleotide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Buformin The therapeutic efficacy of Buformin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Vildagliptin The therapeutic efficacy of Vildagliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Voglibose The therapeutic efficacy of Voglibose can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
NN344 The therapeutic efficacy of NN344 can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
AMG-222 The therapeutic efficacy of AMG-222 can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Bisegliptin The therapeutic efficacy of Bisegliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Liraglutide The therapeutic efficacy of Liraglutide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Gosogliptin The therapeutic efficacy of Gosogliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Glibornuride The therapeutic efficacy of Glibornuride can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Benfluorex The therapeutic efficacy of Benfluorex can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Dulaglutide The therapeutic efficacy of Dulaglutide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Lobeglitazone The therapeutic efficacy of Lobeglitazone can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Netoglitazone The therapeutic efficacy of Netoglitazone can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Rivoglitazone The therapeutic efficacy of Rivoglitazone can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Ciglitazone The therapeutic efficacy of Ciglitazone can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Lixisenatide The therapeutic efficacy of Lixisenatide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Insulin degludec The therapeutic efficacy of Insulin degludec can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Insulin peglispro The therapeutic efficacy of Insulin peglispro can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Insulin tregopil The therapeutic efficacy of Insulin tregopil can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Ipragliflozin The therapeutic efficacy of Ipragliflozin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Dutogliptin The therapeutic efficacy of Dutogliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Allicin The therapeutic efficacy of Allicin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Tofogliflozin The therapeutic efficacy of Tofogliflozin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Teneligliptin The therapeutic efficacy of Teneligliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Omarigliptin The therapeutic efficacy of Omarigliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Carmegliptin The therapeutic efficacy of Carmegliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Gemigliptin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Anagliptin The therapeutic efficacy of Anagliptin can be increased when used in combination with Technetium Tc-99m ciprofloxacin.

Target Protein

DNA gyrase subunit B gyrB
DNA topoisomerase 2-beta TOP2B

Referensi & Sumber

Artikel (PubMed)

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