Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to improve its pharmacological properties by using the company's proprietary albumin fusion technology. Human Genome Sciences is developing Albuferon as a potential treatment for chronic hepatitis C. The drug was under investigation as an alternative to pegylated IFN-?-2a for the treatment of hepatitis C. In response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they ceased development of the drug.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Zidovudine | The risk or severity of adverse effects can be increased when Albinterferon Alfa-2B is combined with Zidovudine. |
| Zolmitriptan | The metabolism of Zolmitriptan can be decreased when combined with Albinterferon Alfa-2B. |
| Caffeine | The metabolism of Caffeine can be decreased when combined with Albinterferon Alfa-2B. |
| Dyphylline | The metabolism of Dyphylline can be decreased when combined with Albinterferon Alfa-2B. |
| Pentoxifylline | The metabolism of Pentoxifylline can be decreased when combined with Albinterferon Alfa-2B. |
| Mercaptopurine | The metabolism of Mercaptopurine can be decreased when combined with Albinterferon Alfa-2B. |
| Oxtriphylline | The metabolism of Oxtriphylline can be decreased when combined with Albinterferon Alfa-2B. |
| Theobromine | The metabolism of Theobromine can be decreased when combined with Albinterferon Alfa-2B. |
| Fenethylline | The metabolism of Fenethylline can be decreased when combined with Albinterferon Alfa-2B. |
| 8-azaguanine | The metabolism of 8-azaguanine can be decreased when combined with Albinterferon Alfa-2B. |
| 7,9-Dimethylguanine | The metabolism of 7,9-Dimethylguanine can be decreased when combined with Albinterferon Alfa-2B. |
| Xanthine | The metabolism of Xanthine can be decreased when combined with Albinterferon Alfa-2B. |
| 7-Deazaguanine | The metabolism of 7-Deazaguanine can be decreased when combined with Albinterferon Alfa-2B. |
| Guanine | The metabolism of Guanine can be decreased when combined with Albinterferon Alfa-2B. |
| 9-Methylguanine | The metabolism of 9-Methylguanine can be decreased when combined with Albinterferon Alfa-2B. |
| Peldesine | The metabolism of Peldesine can be decreased when combined with Albinterferon Alfa-2B. |
| Hypoxanthine | The metabolism of Hypoxanthine can be decreased when combined with Albinterferon Alfa-2B. |
| 9-Deazaguanine | The metabolism of 9-Deazaguanine can be decreased when combined with Albinterferon Alfa-2B. |
| Propentofylline | The metabolism of Propentofylline can be decreased when combined with Albinterferon Alfa-2B. |
| Valomaciclovir | The metabolism of Valomaciclovir can be decreased when combined with Albinterferon Alfa-2B. |
| 3-isobutyl-1-methyl-7H-xanthine | The metabolism of 3-isobutyl-1-methyl-7H-xanthine can be decreased when combined with Albinterferon Alfa-2B. |
| Uric acid | The metabolism of Uric acid can be decreased when combined with Albinterferon Alfa-2B. |
| Doxofylline | The metabolism of Doxofylline can be decreased when combined with Albinterferon Alfa-2B. |
| 6-O-benzylguanine | The metabolism of 6-O-benzylguanine can be decreased when combined with Albinterferon Alfa-2B. |
| Lisofylline | The metabolism of Lisofylline can be decreased when combined with Albinterferon Alfa-2B. |
| Lobucavir | The metabolism of Lobucavir can be decreased when combined with Albinterferon Alfa-2B. |
| Cafedrine | The metabolism of Cafedrine can be decreased when combined with Albinterferon Alfa-2B. |
| Theodrenaline | The metabolism of Theodrenaline can be decreased when combined with Albinterferon Alfa-2B. |
| Bamifylline | The metabolism of Bamifylline can be decreased when combined with Albinterferon Alfa-2B. |
| Proxyphylline | The metabolism of Proxyphylline can be decreased when combined with Albinterferon Alfa-2B. |
| Acefylline | The metabolism of Acefylline can be decreased when combined with Albinterferon Alfa-2B. |
| Etamiphylline | The metabolism of Etamiphylline can be decreased when combined with Albinterferon Alfa-2B. |
| Pentifylline | The metabolism of Pentifylline can be decreased when combined with Albinterferon Alfa-2B. |
| Bufylline | The metabolism of Bufylline can be decreased when combined with Albinterferon Alfa-2B. |
| Bromotheophylline | The metabolism of Bromotheophylline can be decreased when combined with Albinterferon Alfa-2B. |
| Furafylline | The metabolism of Furafylline can be decreased when combined with Albinterferon Alfa-2B. |
| 8-chlorotheophylline | The metabolism of 8-chlorotheophylline can be decreased when combined with Albinterferon Alfa-2B. |
| PCS-499 | The metabolism of PCS-499 can be decreased when combined with Albinterferon Alfa-2B. |
| Fluvoxamine | The metabolism of Fluvoxamine can be decreased when combined with Albinterferon Alfa-2B. |
| Bortezomib | The metabolism of Bortezomib can be decreased when combined with Albinterferon Alfa-2B. |
| Betaxolol | The metabolism of Betaxolol can be decreased when combined with Albinterferon Alfa-2B. |
| Carmustine | The metabolism of Carmustine can be decreased when combined with Albinterferon Alfa-2B. |
| Disopyramide | The metabolism of Disopyramide can be decreased when combined with Albinterferon Alfa-2B. |
| Lidocaine | The metabolism of Lidocaine can be decreased when combined with Albinterferon Alfa-2B. |
| Conjugated estrogens | The metabolism of Conjugated estrogens can be decreased when combined with Albinterferon Alfa-2B. |
| Ropivacaine | The metabolism of Ropivacaine can be decreased when combined with Albinterferon Alfa-2B. |
| Acetaminophen | The metabolism of Acetaminophen can be decreased when combined with Albinterferon Alfa-2B. |
| Olanzapine | The metabolism of Olanzapine can be decreased when combined with Albinterferon Alfa-2B. |
| Chlorzoxazone | The metabolism of Chlorzoxazone can be decreased when combined with Albinterferon Alfa-2B. |
| Clozapine | The metabolism of Clozapine can be decreased when combined with Albinterferon Alfa-2B. |
| Grepafloxacin | The metabolism of Grepafloxacin can be decreased when combined with Albinterferon Alfa-2B. |
| Mirtazapine | The metabolism of Mirtazapine can be decreased when combined with Albinterferon Alfa-2B. |
| Mexiletine | The metabolism of Mexiletine can be decreased when combined with Albinterferon Alfa-2B. |
| Tacrine | The metabolism of Tacrine can be decreased when combined with Albinterferon Alfa-2B. |
| Triamterene | The metabolism of Triamterene can be decreased when combined with Albinterferon Alfa-2B. |
| Promazine | The metabolism of Promazine can be decreased when combined with Albinterferon Alfa-2B. |
| Zolpidem | The metabolism of Zolpidem can be decreased when combined with Albinterferon Alfa-2B. |
| Entecavir | The metabolism of Entecavir can be decreased when combined with Albinterferon Alfa-2B. |
| Nabumetone | The metabolism of Nabumetone can be decreased when combined with Albinterferon Alfa-2B. |
| Quinine | The metabolism of Quinine can be decreased when combined with Albinterferon Alfa-2B. |
| Fluoxetine | The metabolism of Fluoxetine can be decreased when combined with Albinterferon Alfa-2B. |
| Chlorpromazine | The metabolism of Chlorpromazine can be decreased when combined with Albinterferon Alfa-2B. |
| Flutamide | The metabolism of Flutamide can be decreased when combined with Albinterferon Alfa-2B. |
| Haloperidol | The metabolism of Haloperidol can be decreased when combined with Albinterferon Alfa-2B. |
| Albendazole | The metabolism of Albendazole can be decreased when combined with Albinterferon Alfa-2B. |
| Rofecoxib | The metabolism of Rofecoxib can be decreased when combined with Albinterferon Alfa-2B. |
| Cinnarizine | The metabolism of Cinnarizine can be decreased when combined with Albinterferon Alfa-2B. |
| Propranolol | The metabolism of Propranolol can be decreased when combined with Albinterferon Alfa-2B. |
| Diclofenac | The metabolism of Diclofenac can be decreased when combined with Albinterferon Alfa-2B. |
| Imatinib | The metabolism of Imatinib can be decreased when combined with Albinterferon Alfa-2B. |
| Guanabenz | The metabolism of Guanabenz can be decreased when combined with Albinterferon Alfa-2B. |
| Pemetrexed | The metabolism of Pemetrexed can be decreased when combined with Albinterferon Alfa-2B. |
| Verapamil | The metabolism of Verapamil can be decreased when combined with Albinterferon Alfa-2B. |
| Paroxetine | The metabolism of Paroxetine can be decreased when combined with Albinterferon Alfa-2B. |
| Thiabendazole | The metabolism of Thiabendazole can be decreased when combined with Albinterferon Alfa-2B. |
| Riluzole | The metabolism of Riluzole can be decreased when combined with Albinterferon Alfa-2B. |
| Zileuton | The metabolism of Zileuton can be decreased when combined with Albinterferon Alfa-2B. |
| Clopidogrel | The metabolism of Clopidogrel can be decreased when combined with Albinterferon Alfa-2B. |
| Estradiol | The metabolism of Estradiol can be decreased when combined with Albinterferon Alfa-2B. |
| Acyclovir | The metabolism of Acyclovir can be decreased when combined with Albinterferon Alfa-2B. |
| Naproxen | The metabolism of Naproxen can be decreased when combined with Albinterferon Alfa-2B. |
| Trifluoperazine | The metabolism of Trifluoperazine can be decreased when combined with Albinterferon Alfa-2B. |
| Perphenazine | The metabolism of Perphenazine can be decreased when combined with Albinterferon Alfa-2B. |
| Terbinafine | The metabolism of Terbinafine can be decreased when combined with Albinterferon Alfa-2B. |
| Ranitidine | The metabolism of Ranitidine can be decreased when combined with Albinterferon Alfa-2B. |
| Ethanol | The metabolism of Ethanol can be decreased when combined with Albinterferon Alfa-2B. |
| Maprotiline | The metabolism of Maprotiline can be decreased when combined with Albinterferon Alfa-2B. |
| Alosetron | The metabolism of Alosetron can be decreased when combined with Albinterferon Alfa-2B. |
| Lomefloxacin | The metabolism of Lomefloxacin can be decreased when combined with Albinterferon Alfa-2B. |
| Ramelteon | The metabolism of Ramelteon can be decreased when combined with Albinterferon Alfa-2B. |
| Azathioprine | The metabolism of Azathioprine can be decreased when combined with Albinterferon Alfa-2B. |
| Frovatriptan | The metabolism of Frovatriptan can be decreased when combined with Albinterferon Alfa-2B. |
| Levobupivacaine | The metabolism of Levobupivacaine can be decreased when combined with Albinterferon Alfa-2B. |
| Cinacalcet | The metabolism of Cinacalcet can be decreased when combined with Albinterferon Alfa-2B. |
| Selegiline | The metabolism of Selegiline can be decreased when combined with Albinterferon Alfa-2B. |
| Tocainide | The metabolism of Tocainide can be decreased when combined with Albinterferon Alfa-2B. |
| Praziquantel | The metabolism of Praziquantel can be decreased when combined with Albinterferon Alfa-2B. |
| Melatonin | The metabolism of Melatonin can be decreased when combined with Albinterferon Alfa-2B. |
| Primaquine | The metabolism of Primaquine can be decreased when combined with Albinterferon Alfa-2B. |
| Hesperetin | The metabolism of Hesperetin can be decreased when combined with Albinterferon Alfa-2B. |