Amibegron

DB05395

small molecule investigational

Deskripsi

Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.

Struktur Molekul 2D

Berat 403.9
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

668 Data
Valsartan Amibegron may decrease the antihypertensive activities of Valsartan.
Ramipril Amibegron may decrease the antihypertensive activities of Ramipril.
Reserpine Amibegron may decrease the antihypertensive activities of Reserpine.
Remikiren Amibegron may decrease the antihypertensive activities of Remikiren.
Torasemide Amibegron may decrease the antihypertensive activities of Torasemide.
Isradipine Amibegron may decrease the antihypertensive activities of Isradipine.
Olmesartan Amibegron may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Amibegron may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Amibegron may decrease the antihypertensive activities of Nitroprusside.
Diltiazem Amibegron may decrease the antihypertensive activities of Diltiazem.
Minoxidil Amibegron may decrease the antihypertensive activities of Minoxidil.
Treprostinil Amibegron may decrease the antihypertensive activities of Treprostinil.
Amlodipine Amibegron may decrease the antihypertensive activities of Amlodipine.
Nimodipine Amibegron may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Amibegron may decrease the antihypertensive activities of Nisoldipine.
Bendroflumethiazide Amibegron may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Amibegron may decrease the antihypertensive activities of Fosinopril.
Trandolapril Amibegron may decrease the antihypertensive activities of Trandolapril.
Metolazone Amibegron may decrease the antihypertensive activities of Metolazone.
Lercanidipine Amibegron may decrease the antihypertensive activities of Lercanidipine.
Benazepril Amibegron may decrease the antihypertensive activities of Benazepril.
Bosentan Amibegron may decrease the antihypertensive activities of Bosentan.
Enalapril Amibegron may decrease the antihypertensive activities of Enalapril.
Cyclothiazide Amibegron may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Amibegron may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Amibegron may decrease the antihypertensive activities of Mecamylamine.
Losartan Amibegron may decrease the antihypertensive activities of Losartan.
Moexipril Amibegron may decrease the antihypertensive activities of Moexipril.
Eplerenone Amibegron may decrease the antihypertensive activities of Eplerenone.
Lisinopril Amibegron may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Amibegron may decrease the antihypertensive activities of Nitroglycerin.
Metyrosine Amibegron may decrease the antihypertensive activities of Metyrosine.
Hydroflumethiazide Amibegron may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Amibegron may decrease the antihypertensive activities of Cryptenamine.
Perindopril Amibegron may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Amibegron may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Amibegron may decrease the antihypertensive activities of Fenoldopam.
Indapamide Amibegron may decrease the antihypertensive activities of Indapamide.
Tadalafil Amibegron may decrease the antihypertensive activities of Tadalafil.
Eprosartan Amibegron may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Amibegron may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Amibegron may decrease the antihypertensive activities of Quinapril.
Telmisartan Amibegron may decrease the antihypertensive activities of Telmisartan.
Methyldopa Amibegron may decrease the antihypertensive activities of Methyldopa.
Hydrochlorothiazide Amibegron may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Amibegron may decrease the antihypertensive activities of Trichlormethiazide.
Irbesartan Amibegron may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Amibegron may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Amibegron may decrease the antihypertensive activities of Deserpidine.
Pentolinium Amibegron may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Amibegron may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Amibegron may decrease the antihypertensive activities of Diazoxide.
Captopril Amibegron may decrease the antihypertensive activities of Captopril.
Epoprostenol Amibegron may decrease the antihypertensive activities of Epoprostenol.
Bepridil Amibegron may decrease the antihypertensive activities of Bepridil.
Hydralazine Amibegron may decrease the antihypertensive activities of Hydralazine.
Polythiazide Amibegron may decrease the antihypertensive activities of Polythiazide.
Cilazapril Amibegron may decrease the antihypertensive activities of Cilazapril.
Saprisartan Amibegron may decrease the antihypertensive activities of Saprisartan.
Spirapril Amibegron may decrease the antihypertensive activities of Spirapril.
Mibefradil Amibegron may decrease the antihypertensive activities of Mibefradil.
Tienilic acid Amibegron may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Amibegron may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Amibegron may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Amibegron may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Amibegron may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Amibegron may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Amibegron may decrease the antihypertensive activities of Pinacidil.
Temocapril Amibegron may decrease the antihypertensive activities of Temocapril.
Riociguat Amibegron may decrease the antihypertensive activities of Riociguat.
Macitentan Amibegron may decrease the antihypertensive activities of Macitentan.
Hexamethonium Amibegron may decrease the antihypertensive activities of Hexamethonium.
Aliskiren Amibegron may decrease the antihypertensive activities of Aliskiren.
Nicorandil Amibegron may decrease the antihypertensive activities of Nicorandil.
Efonidipine Amibegron may decrease the antihypertensive activities of Efonidipine.
Lacidipine Amibegron may decrease the antihypertensive activities of Lacidipine.
Manidipine Amibegron may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Amibegron may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Amibegron may decrease the antihypertensive activities of Enalaprilat.
Selexipag Amibegron may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Amibegron may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Amibegron may decrease the antihypertensive activities of Imidapril.
BQ-123 Amibegron may decrease the antihypertensive activities of BQ-123.
Tetrahydropalmatine Amibegron may decrease the antihypertensive activities of Tetrahydropalmatine.
Cicletanine Amibegron may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Amibegron may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Amibegron may decrease the antihypertensive activities of Zofenopril.
Guanoxan Amibegron may decrease the antihypertensive activities of Guanoxan.
Delapril Amibegron may decrease the antihypertensive activities of Delapril.
Vincamine Amibegron may decrease the antihypertensive activities of Vincamine.
Linsidomine Amibegron may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Amibegron may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Amibegron may decrease the antihypertensive activities of Tolonidine.
Endralazine Amibegron may decrease the antihypertensive activities of Endralazine.
Cadralazine Amibegron may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Amibegron may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Amibegron may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Amibegron may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Amibegron may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Amibegron may decrease the antihypertensive activities of Guanoclor.

Target Protein

Beta-3 adrenergic receptor ADRB3

Referensi & Sumber

Artikel (PubMed)
  • PMID: 14584972
    Authors unspecified: SR 58611A: SR 58611. Drugs R D. 2003;4(6):380-2.
  • PMID: 10226761
    Montastruc JL, Verwaerde P, Pelat M, Galitzky J, Langin D, Lafontan M, Berlan M: Peripheral cardiovascular actions of SR 58611 A, a beta 3-adrenoceptor agonist, in the dog: lack of central effect. Fundam Clin Pharmacol. 1999;13(2):180-6.

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Sekuens Gen/Protein (FASTA)

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