LD50=807 mg/kg (mouse, oral). Side effects can lead to hypertension, hypotension, headache, dizziness, nervousness and tachycardia. Large overdoses can lead to seizures.
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Bupropion | The excretion of Histamine can be decreased when combined with Bupropion. |
| Tipiracil | The excretion of Tipiracil can be decreased when combined with Histamine. |
| Varenicline | The excretion of Varenicline can be decreased when combined with Histamine. |
| Prazosin | The serum concentration of Prazosin can be increased when it is combined with Histamine. |
| Solriamfetol | The serum concentration of Solriamfetol can be increased when it is combined with Histamine. |
| Choline | The serum concentration of Histamine can be increased when it is combined with Choline. |
| Thiamine | The serum concentration of Histamine can be increased when it is combined with Thiamine. |
| Nicotine | The serum concentration of Histamine can be increased when it is combined with Nicotine. |
| Ranolazine | The serum concentration of Histamine can be increased when it is combined with Ranolazine. |
| Metoprolol | The serum concentration of Histamine can be increased when it is combined with Metoprolol. |
| Disopyramide | The serum concentration of Histamine can be increased when it is combined with Disopyramide. |
| Metformin | The serum concentration of Histamine can be increased when it is combined with Metformin. |
| Aminohippuric acid | The serum concentration of Histamine can be increased when it is combined with Aminohippuric acid. |
| Grepafloxacin | The serum concentration of Histamine can be increased when it is combined with Grepafloxacin. |
| Norepinephrine | The serum concentration of Histamine can be increased when it is combined with Norepinephrine. |
| Progesterone | The serum concentration of Histamine can be increased when it is combined with Progesterone. |
| Imipramine | The serum concentration of Histamine can be increased when it is combined with Imipramine. |
| Quinine | The serum concentration of Histamine can be increased when it is combined with Quinine. |
| Cimetidine | The serum concentration of Histamine can be increased when it is combined with Cimetidine. |
| Guanidine | The serum concentration of Histamine can be increased when it is combined with Guanidine. |
| Lamotrigine | The serum concentration of Histamine can be increased when it is combined with Lamotrigine. |
| Propranolol | The serum concentration of Histamine can be increased when it is combined with Propranolol. |
| Amiloride | The serum concentration of Histamine can be increased when it is combined with Amiloride. |
| Imatinib | The serum concentration of Histamine can be increased when it is combined with Imatinib. |
| Epinephrine | The serum concentration of Histamine can be increased when it is combined with Epinephrine. |
| Flurazepam | The serum concentration of Histamine can be increased when it is combined with Flurazepam. |
| Clopidogrel | The serum concentration of Histamine can be increased when it is combined with Clopidogrel. |
| Estradiol | The serum concentration of Histamine can be increased when it is combined with Estradiol. |
| Ranitidine | The serum concentration of Histamine can be increased when it is combined with Ranitidine. |
| Quinidine | The serum concentration of Histamine can be increased when it is combined with Quinidine. |
| Phenformin | The serum concentration of Histamine can be increased when it is combined with Phenformin. |
| Amantadine | The serum concentration of Histamine can be increased when it is combined with Amantadine. |
| Dinoprostone | The serum concentration of Histamine can be increased when it is combined with Dinoprostone. |
| Phenoxybenzamine | The serum concentration of Histamine can be increased when it is combined with Phenoxybenzamine. |
| Famotidine | The serum concentration of Histamine can be increased when it is combined with Famotidine. |
| Salmeterol | The serum concentration of Histamine can be increased when it is combined with Salmeterol. |
| Dopamine | The serum concentration of Histamine can be increased when it is combined with Dopamine. |
| Probenecid | The serum concentration of Histamine can be increased when it is combined with Probenecid. |
| Diphenhydramine | The serum concentration of Histamine can be increased when it is combined with Diphenhydramine. |
| Quinacrine | The serum concentration of Histamine can be increased when it is combined with Quinacrine. |
| Chlorpheniramine | The serum concentration of Histamine can be increased when it is combined with Chlorpheniramine. |
| Amiodarone | The serum concentration of Histamine can be increased when it is combined with Amiodarone. |
| Desipramine | The serum concentration of Histamine can be increased when it is combined with Desipramine. |
| Oxprenolol | The serum concentration of Histamine can be increased when it is combined with Oxprenolol. |
| Dronedarone | The serum concentration of Histamine can be increased when it is combined with Dronedarone. |
| Vandetanib | The serum concentration of Histamine can be increased when it is combined with Vandetanib. |
| Reserpine | The serum concentration of Reserpine can be increased when it is combined with Histamine. |
| Pramipexole | The serum concentration of Pramipexole can be increased when it is combined with Histamine. |
| Lamivudine | The serum concentration of Lamivudine can be increased when it is combined with Histamine. |
| Memantine | The serum concentration of Memantine can be increased when it is combined with Histamine. |
| Agmatine | The serum concentration of Agmatine can be increased when it is combined with Histamine. |
| Linagliptin | The serum concentration of Linagliptin can be increased when it is combined with Histamine. |
| Nafamostat | The serum concentration of Nafamostat can be increased when it is combined with Histamine. |
| Choline salicylate | The serum concentration of Choline salicylate can be increased when it is combined with Histamine. |
| Pimagedine | The serum concentration of Histamine can be increased when it is combined with Pimagedine. |
| Tafenoquine | The serum concentration of Histamine can be increased when it is combined with Tafenoquine. |
| Crizotinib | The serum concentration of Histamine can be increased when it is combined with Crizotinib. |
| Dolutegravir | The serum concentration of Histamine can be increased when it is combined with Dolutegravir. |
| Lenvatinib | The serum concentration of Histamine can be increased when it is combined with Lenvatinib. |
| Dexchlorpheniramine maleate | The serum concentration of Histamine can be increased when it is combined with Dexchlorpheniramine maleate. |
| Isavuconazole | The serum concentration of Histamine can be increased when it is combined with Isavuconazole. |
| Tucatinib | The serum concentration of Histamine can be increased when it is combined with Tucatinib. |
| Apalutamide | The serum concentration of Histamine can be increased when it is combined with Apalutamide. |
| Erdafitinib | The serum concentration of Histamine can be increased when it is combined with Erdafitinib. |
| Enasidenib | The serum concentration of Histamine can be increased when it is combined with Enasidenib. |
| Estradiol acetate | The serum concentration of Histamine can be increased when it is combined with Estradiol acetate. |
| Estradiol benzoate | The serum concentration of Histamine can be increased when it is combined with Estradiol benzoate. |
| Estradiol cypionate | The serum concentration of Histamine can be increased when it is combined with Estradiol cypionate. |
| Estradiol dienanthate | The serum concentration of Histamine can be increased when it is combined with Estradiol dienanthate. |
| Estradiol valerate | The serum concentration of Histamine can be increased when it is combined with Estradiol valerate. |
| Methylene blue | The serum concentration of Histamine can be increased when it is combined with Methylene blue. |
| Trilaciclib | The serum concentration of Histamine can be increased when it is combined with Trilaciclib. |
| Codeine | The risk or severity of adverse effects can be increased when Codeine is combined with Histamine. |
| Doxazosin | The risk or severity of adverse effects can be increased when Doxazosin is combined with Histamine. |
| Rocuronium | The risk or severity of adverse effects can be increased when Rocuronium is combined with Histamine. |
| Acyclovir | The risk or severity of adverse effects can be increased when Acyclovir is combined with Histamine. |
| Ganciclovir | The risk or severity of adverse effects can be increased when Ganciclovir is combined with Histamine. |
| Pancuronium | The risk or severity of adverse effects can be increased when Pancuronium is combined with Histamine. |
| Palbociclib | The risk or severity of adverse effects can be increased when Palbociclib is combined with Histamine. |
| Dacomitinib | The risk or severity of adverse effects can be increased when Dacomitinib is combined with Histamine. |
| Gilteritinib | The risk or severity of adverse effects can be increased when Gilteritinib is combined with Histamine. |
| Nelfinavir | The risk or severity of adverse effects can be increased when Nelfinavir is combined with Histamine. |
| Indinavir | The risk or severity of adverse effects can be increased when Indinavir is combined with Histamine. |
| Nevirapine | The risk or severity of adverse effects can be increased when Nevirapine is combined with Histamine. |
| Efavirenz | The risk or severity of adverse effects can be increased when Efavirenz is combined with Histamine. |
| Verapamil | The risk or severity of adverse effects can be increased when Verapamil is combined with Histamine. |
| Saquinavir | The risk or severity of adverse effects can be increased when Saquinavir is combined with Histamine. |
| Pitolisant | The risk or severity of adverse effects can be increased when Pitolisant is combined with Histamine. |
| Formoterol | The risk or severity of adverse effects can be increased when Formoterol is combined with Histamine. |
| Guanfacine | The risk or severity of adverse effects can be increased when Guanfacine is combined with Histamine. |
| Cisplatin | The serum concentration of Cisplatin can be increased when it is combined with Histamine. |
| Procainamide | The serum concentration of Procainamide can be increased when it is combined with Histamine. |
| Oxaliplatin | The serum concentration of Oxaliplatin can be increased when it is combined with Histamine. |
| Dalfampridine | The serum concentration of Dalfampridine can be increased when it is combined with Histamine. |
| Dofetilide | The serum concentration of Dofetilide can be increased when it is combined with Histamine. |
| Clofarabine | The serum concentration of Clofarabine can be increased when it is combined with Histamine. |
| Gentamicin | The serum concentration of Gentamicin can be increased when it is combined with Histamine. |
| Pentagastrin | The serum concentration of Histamine can be increased when it is combined with Pentagastrin. |
| Fexinidazole | The serum concentration of Histamine can be increased when it is combined with Fexinidazole. |
| Levoketoconazole | The serum concentration of Histamine can be increased when it is combined with Levoketoconazole. |