Girentuximab

DB05304

biotech investigational

Deskripsi

Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

372 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Girentuximab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Girentuximab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Girentuximab.
Estrone Estrone may increase the thrombogenic activities of Girentuximab.
Estradiol Estradiol may increase the thrombogenic activities of Girentuximab.
Dienestrol Dienestrol may increase the thrombogenic activities of Girentuximab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Girentuximab.
Mestranol Mestranol may increase the thrombogenic activities of Girentuximab.
Estriol Estriol may increase the thrombogenic activities of Girentuximab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Girentuximab.
Quinestrol Quinestrol may increase the thrombogenic activities of Girentuximab.
Hexestrol Hexestrol may increase the thrombogenic activities of Girentuximab.
Tibolone Tibolone may increase the thrombogenic activities of Girentuximab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Girentuximab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Girentuximab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Girentuximab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Girentuximab.
Zeranol Zeranol may increase the thrombogenic activities of Girentuximab.
Equol Equol may increase the thrombogenic activities of Girentuximab.
Promestriene Promestriene may increase the thrombogenic activities of Girentuximab.
Methallenestril Methallenestril may increase the thrombogenic activities of Girentuximab.
Epimestrol Epimestrol may increase the thrombogenic activities of Girentuximab.
Moxestrol Moxestrol may increase the thrombogenic activities of Girentuximab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Girentuximab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Girentuximab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Girentuximab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Girentuximab.
Biochanin A Biochanin A may increase the thrombogenic activities of Girentuximab.
Formononetin Formononetin may increase the thrombogenic activities of Girentuximab.
Estetrol Estetrol may increase the thrombogenic activities of Girentuximab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Girentuximab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Girentuximab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Girentuximab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Girentuximab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Girentuximab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Girentuximab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Girentuximab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Girentuximab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Girentuximab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Girentuximab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Girentuximab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Girentuximab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Girentuximab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Girentuximab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Girentuximab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Girentuximab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Girentuximab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Girentuximab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Girentuximab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Girentuximab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Girentuximab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Girentuximab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Girentuximab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Girentuximab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Girentuximab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Girentuximab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Girentuximab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Girentuximab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Girentuximab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Girentuximab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Girentuximab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Girentuximab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Girentuximab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Girentuximab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Girentuximab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Girentuximab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Girentuximab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Girentuximab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Girentuximab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Girentuximab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Girentuximab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Obiltoxaximab.
XTL-001 The risk or severity of adverse effects can be increased when Girentuximab is combined with XTL-001.
NAV 1800 The risk or severity of adverse effects can be increased when Girentuximab is combined with NAV 1800.
Briakinumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Briakinumab.
Otelixizumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Otelixizumab.
AMG 108 The risk or severity of adverse effects can be increased when Girentuximab is combined with AMG 108.
Iratumumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Iratumumab.
Enokizumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Enokizumab.
Ramucirumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Ramucirumab.
Farletuzumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Farletuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Veltuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Ustekinumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Girentuximab is combined with Trastuzumab emtansine.
PRO-542 The risk or severity of adverse effects can be increased when Girentuximab is combined with PRO-542.
TNX-901 The risk or severity of adverse effects can be increased when Girentuximab is combined with TNX-901.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Girentuximab is combined with Inotuzumab ozogamicin.
RI 624 The risk or severity of adverse effects can be increased when Girentuximab is combined with RI 624.
Stamulumab The risk or severity of adverse effects can be increased when Girentuximab is combined with MYO-029.
CT-011 The risk or severity of adverse effects can be increased when Girentuximab is combined with CT-011.
Leronlimab The risk or severity of adverse effects can be increased when Girentuximab is combined with Leronlimab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Girentuximab is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when Girentuximab is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when Girentuximab is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when Girentuximab is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when Girentuximab is combined with Canakinumab.

Target Protein

Carbonic anhydrase 9 CA9
Interleukin-2 IL2

Referensi & Sumber

Artikel (PubMed)
  • PMID: 17489737
    Carney WP: Circulating oncoproteins HER2/neu, EGFR and CAIX (MN) as novel cancer biomarkers. Expert Rev Mol Diagn. 2007 May;7(3):309-19.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Rencarex

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul