Ecabet

DB05265

small molecule investigational

Deskripsi

Ecabet is a prescription eye drop for the treatment of dry eye syndrome. Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss from tear evaporation. Ecabet is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis.

Struktur Molekul 2D

Berat 380.498
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

39 Data
Darbepoetin alfa The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Ecabet.
Erythropoietin The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Ecabet.
Peginesatide The risk or severity of Thrombosis can be increased when Peginesatide is combined with Ecabet.
Methoxy polyethylene glycol-epoetin beta The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Ecabet.
Lidocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Lidocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Ropivacaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Bupivacaine.
Cinchocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Cinchocaine.
Dyclonine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Dyclonine.
Procaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Procaine.
Prilocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Prilocaine.
Proparacaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Proparacaine.
Meloxicam The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Meloxicam.
Oxybuprocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Oxybuprocaine.
Cocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Cocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Mepivacaine.
Levobupivacaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Levobupivacaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Diphenhydramine.
Benzocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Benzocaine.
Chloroprocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Chloroprocaine.
Phenol The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Phenol.
Tetrodotoxin The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Tetrodotoxin.
Benzyl alcohol The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Benzyl alcohol.
Capsaicin The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Capsaicin.
Etidocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Etidocaine.
Articaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Articaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Tetracaine.
Propoxycaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Propoxycaine.
Pramocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Pramocaine.
Butamben The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Butamben.
Butacaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Butacaine.
Oxetacaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Oxetacaine.
Ethyl chloride The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Ethyl chloride.
Butanilicaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Butanilicaine.
Metabutethamine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Metabutethamine.
Quinisocaine The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Quinisocaine.
Nelarabine The risk or severity of adverse effects can be increased when Nelarabine is combined with Ecabet.
Ambroxol The risk or severity of methemoglobinemia can be increased when Ecabet is combined with Ambroxol.
Etrasimod The risk or severity of immunosuppression can be increased when Ecabet is combined with Etrasimod.

Target Protein

Urease subunit alpha ureC
NADPH oxidase organizer 1 NOXO1

Referensi & Sumber

Synthesis reference: Shinji Narisawa, "Aqueous ecabet sodium solution preparation." U.S. Patent US20040259905, issued December 23, 2004.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Gastrom — Tanabe Mitsubishi, Japan

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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