Rozrolimupab

DB05209

biotech investigational

Deskripsi

Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies to replace existing anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and the prevention of Hemolytic Disease of Newborns (HDN).

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

372 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Rozrolimupab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Rozrolimupab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Rozrolimupab.
Estrone Estrone may increase the thrombogenic activities of Rozrolimupab.
Estradiol Estradiol may increase the thrombogenic activities of Rozrolimupab.
Dienestrol Dienestrol may increase the thrombogenic activities of Rozrolimupab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Rozrolimupab.
Mestranol Mestranol may increase the thrombogenic activities of Rozrolimupab.
Estriol Estriol may increase the thrombogenic activities of Rozrolimupab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Rozrolimupab.
Quinestrol Quinestrol may increase the thrombogenic activities of Rozrolimupab.
Hexestrol Hexestrol may increase the thrombogenic activities of Rozrolimupab.
Tibolone Tibolone may increase the thrombogenic activities of Rozrolimupab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Rozrolimupab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Rozrolimupab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Rozrolimupab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Rozrolimupab.
Zeranol Zeranol may increase the thrombogenic activities of Rozrolimupab.
Equol Equol may increase the thrombogenic activities of Rozrolimupab.
Promestriene Promestriene may increase the thrombogenic activities of Rozrolimupab.
Methallenestril Methallenestril may increase the thrombogenic activities of Rozrolimupab.
Epimestrol Epimestrol may increase the thrombogenic activities of Rozrolimupab.
Moxestrol Moxestrol may increase the thrombogenic activities of Rozrolimupab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Rozrolimupab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Rozrolimupab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Rozrolimupab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Rozrolimupab.
Biochanin A Biochanin A may increase the thrombogenic activities of Rozrolimupab.
Formononetin Formononetin may increase the thrombogenic activities of Rozrolimupab.
Estetrol Estetrol may increase the thrombogenic activities of Rozrolimupab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Rozrolimupab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Rozrolimupab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Rozrolimupab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Rozrolimupab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Rozrolimupab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Rozrolimupab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Rozrolimupab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Rozrolimupab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Rozrolimupab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Rozrolimupab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Rozrolimupab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Rozrolimupab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Rozrolimupab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Rozrolimupab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Rozrolimupab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Rozrolimupab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Rozrolimupab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Rozrolimupab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Rozrolimupab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Rozrolimupab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Rozrolimupab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Rozrolimupab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Rozrolimupab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Rozrolimupab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Rozrolimupab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Rozrolimupab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Rozrolimupab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Rozrolimupab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Rozrolimupab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Rozrolimupab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Rozrolimupab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Rozrolimupab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Rozrolimupab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Rozrolimupab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Rozrolimupab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Rozrolimupab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Rozrolimupab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Rozrolimupab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Rozrolimupab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Rozrolimupab.
Girentuximab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Girentuximab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Obiltoxaximab.
XTL-001 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with XTL-001.
NAV 1800 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with NAV 1800.
Briakinumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Briakinumab.
Otelixizumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Otelixizumab.
AMG 108 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with AMG 108.
Iratumumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Iratumumab.
Enokizumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Enokizumab.
Ramucirumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Ramucirumab.
Farletuzumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Farletuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Veltuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Ustekinumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Trastuzumab emtansine.
PRO-542 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with PRO-542.
TNX-901 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with TNX-901.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Inotuzumab ozogamicin.
RI 624 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with RI 624.
Stamulumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with MYO-029.
CT-011 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with CT-011.
Leronlimab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Leronlimab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when Rozrolimupab is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Canakinumab.

Target Protein

Rhesus blood group D antigen RHD

Referensi & Sumber

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